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SRI-5 (SRI 5)

Also Known As:

SRI 5; N,N'-octamethylenebis-1-aziridineacetamide; NSC-111716

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azirines
    - Aziridines: 14
      - SRI-5: 3

Experts

1.	Furie, Richard A: 1 article (01/2018)
2.	Isenberg, David: 1 article (01/2018)
3.	Kalunian, Kenneth C: 1 article (01/2018)
4.	Linnik, Matthew D: 1 article (01/2018)
5.	Merrill, Joan T: 1 article (01/2018)
6.	Morgan-Cox, Mary-Ann: 1 article (01/2018)
7.	Petri, Michelle: 1 article (01/2018)
8.	Silk, Maria: 1 article (01/2018)
9.	Taha, Rebecca: 1 article (01/2018)
10.	Urowitz, Murray B: 1 article (01/2018)

Related Diseases

1.	Infections 10/09/2023 - "Anti-interferons: Anifrolumab increased BICLA response and SRI 5 to 8, decreased prednisone dosages, with increased herpes zoster infections, but fewer serious adverse events. "
2.	Herpes Zoster 10/09/2023 - "Anti-interferons: Anifrolumab increased BICLA response and SRI 5 to 8, decreased prednisone dosages, with increased herpes zoster infections, but fewer serious adverse events. "
3.	Fatigue 02/01/2016 - "Although key secondary endpoints (time to severe flare, corticosteroid sparing and fatigue) were not met, patients treated with tabalumab had greater SRI-5 response rates in a serologically active subset and improvements in more stringent SRI cut-offs, SELENA-SLEDAI, Physician's Global Assessment, anti-double-stranded DNA antibodies, complement, total B cells and immunoglobulins. "
4.	Central Nervous System Diseases (CNS Diseases) 01/01/2018 - "The combined prevalence of renal, vascular and CNS disease at baseline was 17.6%; these patients had high SRI-5 response rates. "

Related Drugs and Biologics

1.	Prednisone (Sone)
2.	Interferons
3.	Immunoglobulins (Immunoglobulin)
4.	DNA (Deoxyribonucleic Acid)
5.	Complement System Proteins (Complement)
6.	Antibodies
7.	Adrenal Cortex Hormones (Corticosteroids)
8.	anifrolumab
9.	tabalumab