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MEDS433

Inhibitor of the human dihydroorotate dehydrogenase (hDHODH)

Also Known As:

2-oxo-N-(2,3,5,6-tetrafluoro-4-phenylphenyl)-1H-pyrazolo(1,5-a)pyridine-3-carboxamide

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - Pyrazolones: 41
        MEDS433: 3

Experts

1.	Boschi, Donatella: 2 articles (08/2021 - 01/2021)
2.	Gribaudo, Giorgio: 2 articles (08/2021 - 01/2021)
3.	Luganini, Anna: 2 articles (08/2021 - 01/2021)
4.	Mognetti, Barbara: 2 articles (08/2021 - 01/2021)
5.	Sainas, Stefano: 2 articles (08/2021 - 01/2021)
6.	Sibille, Giulia: 2 articles (08/2021 - 01/2021)
7.	Calistri, Arianna: 1 article (08/2021)
8.	Conciatori, Valeria: 1 article (08/2021)
9.	Del Vecchio, Claudia: 1 article (08/2021)
10.	Elder, Elizabeth: 1 article (08/2021)

Related Diseases

1.	Respiratory Syncytial Virus Infections 11/01/2023 - "Taken as a whole, these observations provide new insights for further development of MEDS433, as a promising candidate to develop new strategies for treatment of RSV infections."
2.	Infections 01/01/2021 - "Taken together, these findings suggest that MEDS433 is a promising candidate as either single agent or in combination regimens with existing direct-acting anti-HSV drugs to develop new strategies for treatment of HSV infections."
3.	COVID-19 08/14/2021 - "Taken together, these findings suggest MEDS433 as a potential candidate to develop novel drugs for COVID-19, as well as broad-spectrum antiviral agents exploitable for future CoVs threats."

Related Drugs and Biologics

1.	Antiviral Agents (Antivirals)