Eukaryotic Initiation Factor-5

A eukaryotic initiation factor that interacts with the 40S initiation complex and promotes the hydrolysis of the bound GTP. The hydrolysis of GTP causes the release of EUKARYOTIC INITIATION FACTOR-2 and EUKARYOTIC INITIATION FACTOR-3 from the 40S subunit and the subsequent joining of the 60S ribosomal subunit to the 40S complex to form the functional 80S initiation complex

Also Known As:

Eukaryotic Initiation Factor 5; Eukaryotic Peptide Initiation Factor-5; Eukaryotic Peptide Initiation Factor 5; Initiation Factor-5, Eukaryotic; Peptide Initiation Factor EIF 5; EIF-5; Peptide Initiation Factor EIF-5

Pharmalogical Action Categories:

GTP Phosphohydrolase Activators

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Ribosomal Proteins: 1138
    - Peptide Initiation Factors: 1364
      - Eukaryotic Initiation Factors: 22
        Eukaryotic Initiation Factor-5: 1
  - Intracellular Signaling Peptides and Proteins: 32
    - GTP-Binding Protein Regulators
      - GTPase-Activating Proteins: 445
        Eukaryotic Initiation Factor-5: 1
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - GTP-Binding Protein Regulators
      - GTPase-Activating Proteins: 445
        Eukaryotic Initiation Factor-5: 1

S cerevisiae eIF5A protein

Bio-Agent Context: Research Results