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(4- (bis(4- chlorophenyl)methyl)- 1- piperazinyl)(5- methyl- 4- nitro- 1,2- oxazol- 3- yl)methanone

Also Known As:

GPX4 inhibitor ML210; ML210

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - (4-(bis(4-chlorophenyl)methyl)-1-piperazinyl)(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone: 3
  - Piperazines: 26
    - (4-(bis(4-chlorophenyl)methyl)-1-piperazinyl)(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone: 3

Experts

1.	Dupuy, Adam J: 1 article (05/2022)
2.	Zhu, Eliot Y: 1 article (05/2022)
3.	Bittker, Joshua A: 1 article (02/2012)
4.	Dandapani, Sivaraman: 1 article (02/2012)
5.	Lewis, Timothy A: 1 article (02/2012)
6.	MacPherson, Lawrence: 1 article (02/2012)
7.	Munoz, Benito: 1 article (02/2012)
8.	Palmer, Michelle: 1 article (02/2012)
9.	Schreiber, Stuart L: 1 article (02/2012)
10.	Shimada, Kenichi: 1 article (02/2012)

Related Diseases

1.	Neoplasms (Cancer) 05/17/2022 - "We test the utility of our approach with a pan-cancer analysis of ML210, an inhibitor of GPX4, and a melanoma-focused analysis of inhibitors of BRAFV600. " 02/15/2012 - "This effort led to the identification of two novel molecular probes (PubChem CID 3689413, ML162 and CID 49766530, ML210) with nanomolar potencies and 4-23-fold selectivities, which can potentially be used for identifying oncogene-specific pathways and targets in cancer cells."
2.	Melanoma (Melanoma, Malignant) 05/17/2022 - "We test the utility of our approach with a pan-cancer analysis of ML210, an inhibitor of GPX4, and a melanoma-focused analysis of inhibitors of BRAFV600. "
3.	Calculi (Calculus) 09/01/1998 - "At ureteroscopy, the calculi were present in the upper ureter in 44%, mid-ureter in 37% and lower ureter in 19% of patients; most calculi were > 5 mm. A 7.5 F Wolf semi-rigid ureteroscope was used and the holmium:YAG laser energy delivered using the Sharplan ML210 device at 0.8-1.0 J/pulse. "

Related Drugs and Biologics

1.	Molecular Probes (Molecular Probe)
2.	ML-162

Related Therapies and Procedures

1.	Solid-State Lasers
2.	Ureteroscopes