ninjin'yoeito

a traditional Japanese (Kampo) medicine that originates from China, contains 12 crude drugs: Rehmannia Root, Japanese Angelica Root, Atractylodes Rhizome, Poria Sclerotium, Ginseng, Cinnamon Bark, Polygala Root, Peony Root, Citrus Unshiu Peel, Astragalus Root, Glycyrrhiza, and Schisandra Fruit

Networked: 66 relevant articles (24 outcomes, 21 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Michihara, Seiwa: 7 articles (03/2024 - 01/2021)
2.	Takahashi, Ryuji: 7 articles (03/2024 - 01/2021)
3.	Fujita, Nina: 6 articles (03/2024 - 01/2021)
4.	Han, Li-Kun: 6 articles (03/2024 - 01/2021)
5.	Inui, Akio: 6 articles (01/2024 - 01/2018)
6.	Omiya, Yuji: 6 articles (09/2022 - 01/2021)
7.	Mizuno, Keita: 4 articles (02/2023 - 01/2022)
8.	Imai, Ryota: 4 articles (06/2022 - 01/2021)
9.	Mizoguchi, Kazushige: 4 articles (06/2022 - 01/2021)
10.	Motoo, Yoshiharu: 4 articles (06/2022 - 10/2015)

Related Diseases

1.	Fatigue 01/01/2018 - "Ninjin'yoeito has been associated with both physical effects, such as improvement in overall physical strength and appetite, and reduction in fatigue, and psychological effects, such as greater motivation and reduction of depression and anxiety symptoms. " 01/01/2020 - "Ninjin'yoeito, a traditional Japanese herbal medicine, is used to prevent fatigue, loss of appetite, and coldness of limbs. " 01/01/2018 - "Frequency of subjective fatigue was significantly decreased in patients administered ninjin'yoeito, compared to those treated with LEN-DEX alone (92.3 and 47.8 % of patients with and without ninjin'yoeito, respectively; p = 0.008). " 08/01/2020 - "Ninjin'yoeito (NYT) is a Kampo medicine that has been reported to improve fatigue, psychosomatic vulnerability, and respiratory symptoms. " 01/01/2022 - "Ninjin'yoeito (NYT) is a traditional Japanese Kampo medicine used to treat patients with vulnerable constitution, fatigue or physical exhaustion caused by aging and illness. "
2.	Frailty 01/01/2019 - "As the checklist contains many aspects of frailty, Ninjin'yoeito might be beneficial in preventing frailty. " 01/01/2024 - "This study explores the efficacy of Ninjin'yoeito (NYT) in the early stages of frailty, a critical period for preventive interventions. " 01/01/2021 - "Conclusion: Patients with frailty often have a worsened SF-36 score after discharge following acute illness, but the score may be improved by taking ninjin'yoeito." 06/01/2023 - "In this study, we investigated the potential of Ninjin'yoeito (NYT), a traditional Chinese herbal medicine, as a viable treatment option for frailty. " 01/01/2023 - "This study aimed to investigate the effect of the multicomponent drug, ninjin'yoeito (NYT), on frailty in MCI and mild AD patients. "
3.	Sarcopenia 01/01/2020 - "Good Rehabilitation Outcomes and Improved Nutritional Status After Treatment With the Japanese Herbal Medicine Ninjin'yoeito in an Elderly Patient With Hip Fracture and Sarcopenia: A Case Report." 06/01/2022 - "These results indicate that ninjin'yoeito has considerable potential for improving frailty and sarcopenia in older patients." 01/01/2018 - "Herbal Medicine Ninjin'yoeito in the Treatment of Sarcopenia and Frailty." 12/01/2021 - "Ninjin'yoeito (NYT), a traditional Japanese medicine (Kampo medicine), is reportedly effective in treating frailty and sarcopenia. " 01/01/2020 - "The findings from this case suggest that ninjin'yoeito, which includes Astragalus root and Schisandra fruit, may be an effective treatment option for sarcopenia or frailty with appetite loss and impaired activities of daily living in aged patients."
4.	Anorexia 12/09/2017 - "Here, we conducted an open-label pilot study to determine whether ninjin'yoeito (NYT, TJ-108), a multicomponent drug, is effective for improving anorexia and apathy in patients with AD, and consequently their cognitive function. " 06/01/2019 - "Ninjin-yoeito, a Japanese kampo medicine comprising twelve herbs has been used to treat anorexia. " 10/21/2021 - "Dementia is exacerbated by loss of appetite and amotivation, and recent studies have indicated that ninjin'yoeito improves anorexia and amotivation. " 01/01/2022 - "Abdominal fullness and discomfort induced by an extract of the Japanese herbal medicine Tsumura Ninjin'yoeito: The cases of two patients with Alzheimer's disease and anorexia." 01/01/2022 - "We then prescribed 9.0 g/day of ninjin'yoeito (TJ-108, Tsumura and Co.) to allow recovery from anorexia and subsequently added bukuryoingohangekobokuto (TJ-116, Tsumura and Co.) to treat the persistent nausea. "
5.	Chronic Obstructive Pulmonary Disease (COPD) 08/01/2020 - "Usefulness of Ninjin'yoeito for Chronic Obstructive Pulmonary Disease Patients with Frailty." 01/01/2018 - "This case report illustrates the potential usefulness of Ninjin'yoeito treatment for frailty in patients with COPD." 01/01/2020 - "Ninjin'yoeito Ameliorates Skeletal Muscle Complications in COPD Model Mice by Upregulating Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Expression." 01/01/2018 - "Improvement in Frailty in a Patient With Severe Chronic Obstructive Pulmonary Disease After Ninjin'yoeito Therapy: A Case Report." 01/01/2018 - "Herein, we report the successful management of frailty using Ninjin'yoeito therapy in a 76-year-old patient with COPD. "

Related Drugs and Biologics

1.	ren-shen-yang-rong-tang
2.	Oxaliplatin (Eloxatin)
3.	Iron
4.	Fluorouracil (Carac)
5.	Gemcitabine
6.	130-nm albumin-bound paclitaxel
7.	si-jun-zi-tang
8.	si-wu-tang
9.	Peroxisome Proliferator-Activated Receptors (PPAR)
10.	Prednisone (Sone)

Related Therapies and Procedures

1.	Kampo Medicine (Kampo)
2.	Therapeutics
3.	Adjuvant Chemotherapy
4.	Drug Therapy (Chemotherapy)
5.	Aftercare (After-Treatment)