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pyrrolidine-2,5-dione

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - pyrrolidine-2,5-dione: 7

Experts

1.	Rapacz, Anna: 5 articles (04/2022 - 02/2015)
2.	Obniska, Jolanta: 4 articles (04/2022 - 02/2015)
3.	Kamiński, Krzysztof: 3 articles (04/2022 - 02/2015)
4.	Filipek, Barbara: 3 articles (02/2020 - 03/2016)
5.	Rybka, Sabina: 3 articles (02/2020 - 02/2015)
6.	Góra, Małgorzata: 2 articles (04/2022 - 02/2020)
7.	Pękala, Elżbieta: 2 articles (02/2020 - 03/2016)
8.	Sałat, Kinga: 2 articles (03/2016 - 02/2015)
9.	Czopek, Anna: 1 article (04/2022)
10.	Dziubina, Anna: 1 article (04/2022)

Related Diseases

1.	Pain (Aches) 02/15/2020 - "In conclusion, the tested pyrrolidine-2,5-dione derivatives with antiseizure activity exerted also analgesic and antiallodynic effects in mouse models of pain." 04/06/2022 - "In this context, the analgesic effect of four pyrrolidine-2,5-dione derivatives (compounds 3, 4, 6, and 9), with previously confirmed anticonvulsant and preliminary antinociceptive activity, was assessed in established pain models. " 02/01/2015 - "Antinociceptive properties of N-Mannich bases derived from 3-substituted pyrrolidine-2,5-dione in the formalin model of persistent pain in mice."
2.	Seizures (Absence Seizure) 01/01/2018 - "Here, we investigated the anticonvulsant activity of six new hybrid compounds based on the pyrrolidine-2,5-dione scaffold in the 6 Hz corneal stimulation test with 44 mA stimulus intensity in mice, which is the model of pharmacoresistant seizures. "
3.	Sarcoma 180 01/01/1989 - "(R,S)3-(N,N-[bis-(2-chloroethyl)]-amino)-1-(2'-methoxyphenyl)- pyrrolidine-2,5-dione hydrochloride (I) has shown antitumor activity against P388 and L1210 leukaemias and Sarcoma 180 (ascites). "
4.	Epilepsy (Aura) 03/01/2016 - "The aim of the present experiments was to examine anticonvulsant activity of new pyrrolidine-2,5-dione and 3-methylpyrrolidine-2,5-dione derivatives in animal models of epilepsy. "
5.	Breast Neoplasms (Breast Cancer) 01/01/2021 - "compound H13, which was at-least 10-fold more potent compared to the corresponding pyrrolidine-2,5-dione, in colon and breast cancer cells. "

Related Drugs and Biologics

1.	Anticonvulsants (Antiepileptic Drugs)
2.	Analgesics (Analgesic Drugs)
3.	Mannich Bases
4.	Formaldehyde (Formol)