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AK106-001616

inhibitor of the cytosolic phospholipase A2

Also Known As:

3-(3-Amino-4-(indan-2-yloxy)-5-(1-methyl-1H-indazol-5-yl)-phenyl)-propionic acid; AK-106

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kozaki, Tomohito: 2 articles (01/2019 - 01/2015)
2.	Endo, Yukiko: 1 article (01/2019)
3.	Ito, Akitoshi: 1 article (01/2019)
4.	Komatsu, Masakazu: 1 article (01/2019)
5.	Kuriyama, Hiroshi: 1 article (01/2019)
6.	Nakamura, Junji: 1 article (01/2019)
7.	Saito, Kenichi: 1 article (01/2019)
8.	Sakurada, Katsuhiko: 1 article (01/2019)
9.	Shimizu, Hirotomo: 1 article (01/2019)
10.	Shoda, Motoshi: 1 article (01/2019)

Related Diseases

1.	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/01/2019 - "AK106-001616, a Potent and Selective Inhibitor of Cytosolic Phospholipase A2: In Vivo Efficacy for Inflammation, Neuropathic Pain, and Pulmonary Fibrosis."
2.	Neuralgia (Stump Neuralgia) 01/01/2019 - "AK106-001616 dose dependently reversed the decrease in paw withdrawal threshold not only in rat carrageenan-induced hyperalgesia, but also in a rat neuropathic pain model induced by sciatic nerve chronic constriction injury (CCI). " 01/01/2019 - "AK106-001616, a Potent and Selective Inhibitor of Cytosolic Phospholipase A2: In Vivo Efficacy for Inflammation, Neuropathic Pain, and Pulmonary Fibrosis."
3.	Inflammation (Inflammations) 01/01/2019 - "AK106-001616, a Potent and Selective Inhibitor of Cytosolic Phospholipase A2: In Vivo Efficacy for Inflammation, Neuropathic Pain, and Pulmonary Fibrosis."
4.	Hyperalgesia 01/01/2019 - "AK106-001616 dose dependently reversed the decrease in paw withdrawal threshold not only in rat carrageenan-induced hyperalgesia, but also in a rat neuropathic pain model induced by sciatic nerve chronic constriction injury (CCI). "
5.	Fibrosis (Cirrhosis) 01/01/2019 - "Furthermore, AK106-001616 reduced the disease score of bleomycin-induced lung fibrosis in rats. "

Related Drugs and Biologics

1.	Phospholipases A2 (Phospholipase A2)
2.	Leukotrienes
3.	Naproxen (Naprosyn)
4.	Methotrexate (Mexate)
5.	Collagen
6.	Carrageenan
7.	Bleomycin (Blenoxane)
8.	PLIalpha