SOX Transcription Factors

A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN. Many SOX transcription factors play important roles in regulating CELL DIFFERENTIATION. The numerous members of this family are organized in several subgroups according to structural identities found within the proteins.

Also Known As:

SOX Family of Transcription Factors; SOX Transcription Factor Family; SRY (Sex Determining Region Y)-Box Proteins; Transcription Factors, SOX

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Transcription Factors: 38804
    - SOX Transcription Factors: 23
  - Nuclear Proteins: 2678
    - Non-Histone Chromosomal Proteins: 44
      - High Mobility Group Proteins: 63
        SOX Transcription Factors: 23
  - DNA-Binding Proteins: 2009
    - SOX Transcription Factors: 23
  - Nucleoproteins: 1870
    - Non-Histone Chromosomal Proteins: 44
      - High Mobility Group Proteins: 63
        SOX Transcription Factors: 23

Xenopus sox4 protein

Bio-Agent Context: Research Results