Lymphocyte Specific Protein Tyrosine Kinase p56(lck)

This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.

Also Known As:

p56 lck; Proto-Oncogene Protein c-lck; Proto-Oncogene Protein lck; Kinase, lck; Protein c-lck, Proto-Oncogene; Protein lck, Proto-Oncogene; Proto Oncogene Protein c lck; Proto Oncogene Protein lck; c-lck, Proto-Oncogene Protein; lck, Proto-Oncogene Protein; Protein Tyrosine Kinase p56(lck); lck Kinase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        src-Family Kinases: 1640
        Lymphocyte Specific Protein Tyrosine Kinase p56(lck): 49
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - src-Family Kinases: 1640
        Lymphocyte Specific Protein Tyrosine Kinase p56(lck): 49
  - Neoplasm Proteins: 2
    - Oncogene Proteins: 7793
      - Proto-Oncogene Proteins: 7
        Lymphocyte Specific Protein Tyrosine Kinase p56(lck): 49

human LCK protein

Bio-Agent Context: Research Results