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procyanidin trimer C1

a flavonoid found in multiple plant sources including grape, apple, and cacao, which has antioxidant and anti-inflammatory properties

Also Known As:

procyanidin C1

Networked: 11 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        procyanidin trimer C1: 11
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        procyanidin trimer C1: 11

Experts

1.	Chen, Kai-Xian: 2 articles (08/2019 - 08/2016)
2.	Jia, Qi: 2 articles (08/2019 - 08/2016)
3.	Li, Yi-Ming: 2 articles (08/2019 - 08/2016)
4.	Sun, Peng: 2 articles (08/2019 - 08/2016)
5.	Wang, He-Yao: 2 articles (08/2019 - 08/2016)
6.	Wang, Ting: 2 articles (08/2019 - 08/2016)
7.	Byun, Myung-Woo: 2 articles (02/2013 - 11/2012)
8.	Koteswari, Laxmi L: 1 article (11/2020)
9.	Kumar, Anil B: 1 article (11/2020)
10.	Kumari, Seema: 1 article (11/2020)

Related Diseases

1.	Neoplasm Metastasis (Metastasis) 12/01/2013 - "This illustrates that procyanidin C1 is the main active compound in the CC extract responsible for EMT inhibition and that procyanidin C1 could be useful as a lead compound to develop inhibitors of cancer metastasis and other diseases related to EMT." 07/20/2023 - "Procyanidin C1 inhibits tumor growth and metastasis in colon cancer via modulating miR-501-3p/HIGD1A axis." 11/01/2023 - "Both PIEZO1 depletion by shRNA and CTGF inhibition by Procyanidin C1 enhanced the efficacy of 5-FU in suppressing the GC cell peritoneal metastasis. "
2.	Insulin Resistance 08/14/2019 - "Mechanism studies further suggested that procyanidin C1 activates the AKT-eNOS pathway, thus up-regulating glucose uptake and enhancing insulin sensitivity in mature adipocytes. "
3.	Breast Neoplasms (Breast Cancer) 11/01/2020 - "This study indicates the antiproliferative property of procyanidin C1 against breast cancer cells by inducing apoptosis." 11/01/2020 - "A comparative anticancer study on procyanidin C1 against receptor positive and receptor negative breast cancer."
4.	Neoplasms (Cancer) 12/01/2013 - "This illustrates that procyanidin C1 is the main active compound in the CC extract responsible for EMT inhibition and that procyanidin C1 could be useful as a lead compound to develop inhibitors of cancer metastasis and other diseases related to EMT." 11/01/2020 - "Procyanidin C1 decreased the level of Bcl-2 but increased the BAX, caspase 3 and 9 expression in cancer cells. " 07/20/2023 - "Procyanidin C1 inhibits tumor growth and metastasis in colon cancer via modulating miR-501-3p/HIGD1A axis."
5.	Melanoma (Melanoma, Malignant) 01/01/2020 - "Procyanidin C1 Inhibits Melanoma Cell Growth by Activating 67-kDa Laminin Receptor Signaling."

Related Drugs and Biologics

1.	Small Interfering RNA (siRNA)
2.	Fluorouracil (Carac)
3.	Glucose (Dextrose)
4.	Catechin (Z 7300)
5.	procyanidin B2
6.	Caspase 3 (Caspase-3)
7.	Toll-Like Receptor 4
8.	Laminin Receptors
9.	Phloretin
10.	Flavonoids

Related Therapies and Procedures

1.	Therapeutics
2.	Oral Administration