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pinacol

Networked: 11 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Alcohols: 595
  - Glycols: 38
    - pinacol: 11

Experts

1.	Jeong, Young-Il: 2 articles (12/2021 - 01/2020)
2.	Choi, Seon-Hee: 1 article (12/2021)
3.	Kang, Dae-Hwan: 1 article (12/2021)
4.	Kim, Jungsoo: 1 article (12/2021)
5.	Lee, Hye-Lim: 1 article (12/2021)
6.	Yang, Ju-Il: 1 article (12/2021)
7.	Yu, Young-Bob: 1 article (12/2021)
8.	Hu, Kaiyao: 1 article (10/2021)
9.	Huang, Jialu: 1 article (10/2021)
10.	Jiang, Ying: 1 article (10/2021)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2019 - "The pinacol boronate ester derivative (3) showed interesting cytotoxicity against a panel of cancerous cell lines attested by a cancer cell growth-inhibitory potency (GI50) as low as 30 nM." 03/09/2023 - "Moreover, tetraphenylethylene-1-phenyvinyl-pyridine-phenylboronic acid pinacol ester nanoparticles produced a glutathione-depleting adjuvant, quinone methide, which greatly reduced the glutathione level in cancer cells, thus enhancing the efficacy of photodynamic therapy. " 01/01/2021 - "In this report, a cancer cell and mitochondria dual-targeting drug delivery system (DT-NP) is presented based on nanoparticles self-assembled from amphiphilic block copolymers with pH-responsive release of cinnamaldehyde (CA), which is used to encapsulate reactive oxygen species (ROS)-activable prodrug, phenylboronic pinacol ester-caged doxorubicin (BDOX). " 01/01/2020 - "Reactive oxygen species-sensitive nanophotosensitizers of aminophenyl boronic acid pinacol ester conjugated chitosan-g-methoxy poly(ethylene glycol) copolymer for photodynamic treatment of cancer."
2.	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/25/2021 - "Reactive Oxygen Species-Sensitive Nanophotosensitizers of Methoxy Poly(ethylene glycol)-Chlorin e6/Phenyl Boronic Acid Pinacol Ester Conjugates Having Diselenide Linkages for Photodynamic Therapy of Cervical Cancer Cells." 12/25/2021 - "The aim of this study is to fabricate nanophotosensitizers composed of methoxy poly(ethylene glycol) (mPEG), chlorin e6 (Ce6), and phenylboronic acid pinacol ester (PBAP) with diselenide linkages for reactive oxygen species (ROS)-sensitive photodynamic therapy (PDT) of cervical cancer cells. "
3.	Dehydration (Water Stress) 05/11/2006 - "Dehydration mechanisms involving hydride transfer, pinacol rearrangement, or substitution reactions have barriers between 20 and 25 kcal mol(-1). " 11/10/2022 - "For this, the threefold intramolecular olefin metathesis of 3,5-bis(alkenyloxy)phenylboroxines with various lengths of alkenyl chains, formed by the dehydration of the corresponding boronic acid substrates, together with treatment with pinacol, was used to produce 39-, 45-, and 51-membered macrocyclic compounds with three boronate units. " 01/01/2017 - "In the first step, the phosphotungstic acid (HPW)-catalyzed pinacol dehydration in 1-ethyl-3-methylimidazolium chloride ([emim]Cl) selectively affords 2,3-dimethylbutadiene. " 01/01/2020 - "Propargyl alcohols, on treatment with MHMDS (M=Na, K), B2 (pin)2 , an acid chloride and a palladium/copper co-catalyst system, undergo a reaction cascade comprised of trans-diboration, regioselective acylation, cyclization and dehydration to give trisubstituted furylboronic acid pinacol ester derivatives in good yields; subsequent Suzuki coupling allows a fourth substituent of choice to be introduced and hence tetrasubstituted (arylated) furans to be formed. "
4.	Mitochondrial Diseases (Mitochondrial Disease) 03/09/2023 - "The results showed that tetraphenylethylene-1-phenyvinyl-pyridine-phenylboronic acid pinacol ester nanoparticles exhibited a highly efficient photodynamic ablation of MCF-7 cells compared to tetraphenylethylene-1-phenyvinyl-pyridine-phenylboronic acid nanoparticles, upon white light irradiation, due to its high intracellular reactive oxygen species generation efficiency and mitochondria-dysfunction ability. "
5.	Mouth Neoplasms (Oral Cancer) 10/11/2022 - "Nanophotosensitizers Composed of Phenyl Boronic Acid Pinacol Ester-Conjugated Chitosan Oligosaccharide via Thioketal Linker for Reactive Oxygen Species-Sensitive Delivery of Chlorin e6 against Oral Cancer Cells."

Related Drugs and Biologics

1.	Esters
2.	Acids
3.	Glutathione (Reduced Glutathione)
4.	quinone methide
5.	Reactive Oxygen Species (Oxygen Radicals)
6.	Ethylene Glycol (Monoethylene Glycol)
7.	phytochlorin
8.	benzeneboronic acid
9.	monomethoxypolyethylene glycol (MPEG)
10.	1-phenyl-3,3-dimethyltriazene (PDT)

Related Therapies and Procedures

1.	Photochemotherapy (Photodynamic Therapy)