Heat Shock Transcription Factors

Heat and cold stress-inducible, transcription factors that bind to inverted 5'-NGAAN-3' pentamer DNA sequences and are regulated by POLY-ADP-RIBOSYLATION. They play essential roles as transcriptional activators of the HEAT-SHOCK RESPONSE by inducing expression of large classes of MOLECULAR CHAPERONES and heat-shock proteins. They also function in DNA REPAIR; transcriptional reactivation of latent HIV-1; and pre-mRNA processing and nuclear export of HSP70 HEAT-SHOCK PROTEINS during heat stress.

Also Known As:

Heat Shock Factor Protein 1; Heat Shock Factor, Plant; Heat Shock Transcription Factor; Heat Shock Transcription Factor 1; Heat Stress Transcription Factors; Plant Heat Shock Factors; Heat Stress Transcription Factor; Plant Heat Shock Factor

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Transcription Factors: 38804
    - Heat Shock Transcription Factors: 173
  - Carrier Proteins: 12999
    - Poly-ADP-Ribose Binding Proteins
      - Heat Shock Transcription Factors: 173
  - Nuclear Proteins: 2678
    - Poly-ADP-Ribose Binding Proteins
      - Heat Shock Transcription Factors: 173
  - DNA-Binding Proteins: 2009
    - Heat Shock Transcription Factors: 173

human HSF1 protein

Bio-Agent Context: Research Results