Ku Autoantigen

An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.

Also Known As:

G22P1 Antigen; Ku Antigen; Ku Autoantigen, 70 kDa; Ku Autoantigen, 80 kDa; Ku Heterodimer; Ku Protein; Ku70 Antigen; Ku80 Antigen; X-ray Repair Cross-Complementing Protein 5; X-ray Repair Cross-Complementing Protein 6; XRCC5 Protein; XRCC6 Protein; Antigen, G22P1; Antigen, Ku; Antigen, Ku70; Antigen, Ku80; Autoantigen, Ku; Heterodimer, Ku; X ray Repair Cross Complementing Protein 5; X ray Repair Cross Complementing Protein 6

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Acid Anhydride Hydrolases
      - Adenosine Triphosphatases: 8623
        DNA Helicases: 627
        Ku Autoantigen: 73
  - Isomerases: 463
    - DNA Helicases: 627
      - Ku Autoantigen: 73
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Poly-ADP-Ribose Binding Proteins
      - Ku Autoantigen: 73
  - Nuclear Proteins: 2678
    - Nuclear Antigens: 1661
      - Ku Autoantigen: 73
    - Poly-ADP-Ribose Binding Proteins
      - Ku Autoantigen: 73
  - DNA-Binding Proteins: 2009
    - Ku Autoantigen: 73
Biological Factors: 2472
- Antigens: 143924
  - Nuclear Antigens: 1661
    - Ku Autoantigen: 73

rat Xrcc5 protein

Bio-Agent Context: Research Results