picroside-III

structure in first source

Networked: 2 relevant articles (2 outcomes, 2 trials/studies)

1.	Colitis 11/27/2023 - "Picroside III Ameliorates Colitis in Mice: A Study Based on Colon Transcriptome and Fecal 16S Amplicon Profiling." 06/01/2023 - "Picroside III, an Active Ingredient of Picrorhiza scrophulariiflora, Ameliorates Experimental Colitis by Protecting Intestinal Barrier Integrity." 06/01/2023 - "In conclusion, this study demonstrates that Picroside III attenuated DSS-induced colitis by promoting colonic mucosal wound healing and epithelial barrier function recovery via the activation of AMPK." 06/01/2023 - "Results show that Picroside III significantly alleviated clinical signs of colitis including body weight loss, disease activity index increase, colon shortening, and colon tissue damage. " 06/01/2023 - "This study aims to explore the protective effects of Picroside III, an active ingredient of Picrorhiza scrophulariiflora, on the intestinal epithelial barrier in tumor necrosis factor-α (TNF-α) induced Caco-2 cells and dextran sulfate sodium (DSS) induced colitis in mice. "
2.	Body Weight (Weight, Body) 06/01/2023 - "Results show that Picroside III significantly alleviated clinical signs of colitis including body weight loss, disease activity index increase, colon shortening, and colon tissue damage. "

1.	Dextran Sulfate
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)