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Pulsatilla saponin D

has antineoplastic activity; isolated from Pulsatilla chinensis; structure in first source

Also Known As:

SB365 compound

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - Pulsatilla saponin D: 8

Experts

1.	Hong, Soon-Sun: 4 articles (03/2020 - 01/2013)
2.	Jung, Kyung Hee: 4 articles (03/2020 - 01/2013)
3.	Lee, Hee-Seung: 3 articles (09/2013 - 01/2013)
4.	Son, Mi Kwon: 3 articles (09/2013 - 01/2013)
5.	Chen, Meiwan: 2 articles (10/2020 - 01/2015)
6.	He, Chengwei: 2 articles (10/2020 - 01/2015)
7.	Wan, Jian-Bo: 2 articles (10/2020 - 01/2015)
8.	Wang, Kai: 2 articles (10/2020 - 01/2015)
9.	Hong, Sang-Won: 2 articles (09/2013 - 01/2013)
10.	Yan, Hong Hua: 2 articles (09/2013 - 08/2013)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2020 - "SB365, Pulsatilla saponin D, is known to induce apoptosis and inhibit the growth of many cancer cells. " 09/01/2013 - "SB365, Pulsatilla saponin D isolated from the root of Pulsatilla koreana, has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer. " 01/01/2015 - "Pulsatilla saponin D (SB365), a saponin isolated from rhizoma of Pulsatilla chinensis (Bunge) Regel, exhibited anticancer activities in various cancer types. "
2.	Pancreatic Neoplasms (Pancreatic Cancer) 08/01/2013 - "SB365, Pulsatilla saponin D suppresses proliferation and induces apoptosis of pancreatic cancer cells."
3.	Glioblastoma (Glioblastoma Multiforme) 09/05/2019 - "SB365, Pulsatilla Saponin D Induces Caspase-Independent Cell Death and Augments the Anticancer Effect of Temozolomide in Glioblastoma Multiforme Cells."
4.	Colonic Neoplasms (Colon Cancer) 01/01/2013 - "SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway."
5.	Ulcerative Colitis 09/01/2020 - "In this paper, the release performance of Pulsatilla saponin D in PTS and the ulcerative colitis model induced by TNBS in rats were used to evaluate the targeting of PTS composite particle design powder in colon. "

Related Drugs and Biologics

1.	Caspases
2.	Saponins
3.	Proteins (Proteins, Gene)
4.	Powders
5.	Camptothecin
6.	Temozolomide (Temodar)