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homoegonol

has anti-asthmatic activity; structure in first source

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Ahn, Kyung-Seop: 2 articles (12/2014 - 01/2014)
2.	Lee, Kyeong: 2 articles (12/2014 - 01/2014)
3.	Oh, Sei-Ryang: 2 articles (12/2014 - 01/2014)
4.	Barbosa Araújo, Alba Regina: 1 article (01/2021)
5.	Ferreira, Natália Helen: 1 article (01/2021)
6.	Francielli De Oliveira, Pollyanna: 1 article (01/2021)
7.	Furtado, Ricardo Andrade: 1 article (01/2021)
8.	Leandro, Luis Fernando: 1 article (01/2021)
9.	Pauletti, Patrícia Mendonça: 1 article (01/2021)
10.	Tavares, Denise Crispim: 1 article (01/2021)

Related Diseases

1.	Asthma (Bronchial Asthma) 01/01/2014 - "These findings indicate that homoegonol effectively suppresses the asthmatic responses induced by OVA challenge and suggests that homoegonol exhibits potential as therapeutic drug for allergic asthma." 01/01/2014 - "We investigated the efficacy of homoegonol for the treatment of allergic asthma using an ovalbumin (OVA)-induced murine asthma model. " 12/01/2014 - "Homoegonol is a biologically active neolignan isolated from Styrax species with cytotoxic, antimicrobial, anti-inflammatory and anti-asthma activities. "
2.	Inflammation (Inflammations) 01/01/2014 - "The histological analysis of the lung tissue revealed that the administration of homoegonol attenuated the airway inflammation and the mucus overproduction in airway epithelial lesions induced by OVA through a reduction in expression of inducible nitric oxide synthase and matrix metalloproteinase-9. " 12/09/2015 - "The effects of the isolated norneolignans, egonol and homoegonol, on lipopolysaccharide (LPS)-induced nitric oxide (NO) production, reactive oxygen species (ROS) production, and biomarkers of inflammation were evaluated. "
3.	Carcinogenesis 01/01/2021 - "Taken together, these findings suggested the chemopreventive effect attributed to SCHE in colon carcinogenesis, may be related to its capacity to inhibit DNA damage as well as an antioxidant action associated with its chemical constituents egonol and homoegonol."
4.	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 06/01/2005 - "An ethanolic extract from the stems of Styrax camporum Pohl (Styracaceae), a plant traditionally used for gastrointestinal diseases, was fractionated and subjected to flash chromatography and afforded two benzofuran lignans, egonol and homoegonol, and one furofuran lignan, (+/-)syringaresinol, which were identified by spectral data interpretation. "

Related Drugs and Biologics

1.	Ovalbumin
2.	Lignans
3.	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
4.	Matrix Metalloproteinase 9 (Gelatinase B)
5.	Reactive Oxygen Species (Oxygen Radicals)
6.	Biomarkers (Surrogate Marker)
7.	Nitric Oxide (Nitrogen Monoxide)
8.	Lipopolysaccharides
9.	Antioxidants
10.	benzofuran