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chromomycin A2

has antineoplastic activity; structure in first source

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ratovitski, Edward A: 1 article (08/2016)
2.	Costa-Lotufo, Letícia Veras: 1 article (12/2014)
3.	Deusdênia Loiola Pessoa, Otília: 1 article (12/2014)
4.	Freitas, Hozana Patrícia S: 1 article (12/2014)
5.	Guimarães, Larissa Alves: 1 article (12/2014)
6.	Jimenez, Paula Christine: 1 article (12/2014)
7.	Martín, Jesús: 1 article (12/2014)
8.	Reyes, Fernando: 1 article (12/2014)
9.	Rocha, Danilo Damasceno: 1 article (12/2014)
10.	Sousa, Thiciana da Silva: 1 article (12/2014)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 08/16/2016 - "In this study, we observed that the selected marine life-derived compounds (Chromomycin A2, Psammaplin A, and Ilimaquinone) induce expression of several autophagic signaling intermediates in human squamous cell carcinoma, glioblastoma, and colorectal carcinoma cells in vitro through a transcriptional regulation by tumor protein (TP)-p53 family members. "
2.	Neoplasms (Cancer) 08/16/2016 - "In this study, we observed that the selected marine life-derived compounds (Chromomycin A2, Psammaplin A, and Ilimaquinone) induce expression of several autophagic signaling intermediates in human squamous cell carcinoma, glioblastoma, and colorectal carcinoma cells in vitro through a transcriptional regulation by tumor protein (TP)-p53 family members. "
3.	Melanoma (Melanoma, Malignant) 12/04/2014 - "The present study highlights the biological effects of chromomycin A2 toward metastatic melanoma cells in culture. " 12/04/2014 - "MALME-3M, a metastatic melanoma cell line, showed the highest sensitivity to chromomycin A2 after 48h incubation, and was chosen as a model to investigate this potent cytotoxic effect. " 12/04/2014 - "Chromomycin A2 induces autophagy in melanoma cells."
4.	Glioblastoma (Glioblastoma Multiforme) 08/16/2016 - "In this study, we observed that the selected marine life-derived compounds (Chromomycin A2, Psammaplin A, and Ilimaquinone) induce expression of several autophagic signaling intermediates in human squamous cell carcinoma, glioblastoma, and colorectal carcinoma cells in vitro through a transcriptional regulation by tumor protein (TP)-p53 family members. "
5.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 08/16/2016 - "In this study, we observed that the selected marine life-derived compounds (Chromomycin A2, Psammaplin A, and Ilimaquinone) induce expression of several autophagic signaling intermediates in human squamous cell carcinoma, glioblastoma, and colorectal carcinoma cells in vitro through a transcriptional regulation by tumor protein (TP)-p53 family members. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	ilimaquinone
3.	psammaplin A