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STF-118804

a nicotinamide phosphoribosyl transferase inhibitor; structure in first source

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chini, Claudia C S: 1 article (10/2017)
2.	Chini, Eduardo N: 1 article (10/2017)
3.	Dutta, Shamit: 1 article (10/2017)
4.	Espindola-Netto, Jair Machado: 1 article (10/2017)
5.	Mukhopadhyay, Debabrata: 1 article (10/2017)
6.	Pal, Krishnendu: 1 article (10/2017)
7.	Sola-Penna, Mauro: 1 article (10/2017)
8.	Tarragó, Mariana: 1 article (10/2017)
9.	Wang, Enfeng: 1 article (10/2017)
10.	Bassik, Michael C: 1 article (11/2013)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 10/17/2017 - "Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer."
2.	Leukemia 11/21/2013 - "The lead compound STF-118804 is a highly specific NAMPT inhibitor, improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia, and targets leukemia stem cells. " 11/21/2013 - "Using high-throughput chemical and genetic screening, Matheny and colleagues (in this issue of Chemistry & Biology) identified STF-118804, an inhibitor of nicotinamide phosphoribosyltransferase, as a cell type-specific inhibitor of mixed-lineage leukemia with MLL chromosomal rearrangements. "
3.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/21/2013 - "The lead compound STF-118804 is a highly specific NAMPT inhibitor, improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia, and targets leukemia stem cells. "
4.	Neoplasms (Cancer) 10/17/2017 - "Both STF-118804 and FK866 reduced tumor size after 21 days of treatment. "
5.	Adenocarcinoma 10/17/2017 - "We now tested the effect of STF-118804, a new highly specific NAMPT inhibitor, in models of pancreatic ductal adenocarcinoma. "

Related Drugs and Biologics

1.	Nicotinamide Phosphoribosyltransferase