Paul J van Diest Selected Research

Estrogen Receptor alpha

5/2024	Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.
2/2021	Elastosis in ERα-positive male breast cancer.
1/2018	Receptor Conversion in Distant Breast Cancer Metastases: A Systematic Review and Meta-analysis.
1/2018	Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer.
8/2017	Loss of steroid hormone receptors is common in malignant pleural and peritoneal effusions of breast cancer patients treated with endocrine therapy.
10/2011	ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study.
1/2010	ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study.
1/2010	Receptor conversion in distant breast cancer metastases.

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Paul J van Diest Research Topics

Disease

170	Neoplasms (Cancer) 05/2024 - 01/2002
156	Breast Neoplasms (Breast Cancer) 05/2024 - 01/2002
34	Neoplasm Metastasis (Metastasis) 02/2024 - 03/2003
27	Hypoxia (Hypoxemia) 04/2020 - 01/2002
21	Noninfiltrating Intraductal Carcinoma (DCIS) 04/2023 - 11/2003
18	Carcinogenesis 01/2022 - 11/2002
13	Carcinoma (Carcinomatosis) 01/2018 - 07/2003
12	Male Breast Neoplasms (Male Breast Cancer) 01/2020 - 03/2012
9	Prostatic Neoplasms (Prostate Cancer) 10/2021 - 02/2007
8	Melanoma (Melanoma, Malignant) 02/2024 - 11/2004
7	Neoplasm Micrometastasis 06/2010 - 11/2004
6	Lymphatic Metastasis 01/2022 - 06/2009
6	Necrosis 04/2020 - 07/2005
6	Squamous Cell Carcinoma of Head and Neck 01/2018 - 06/2009
5	Triple Negative Breast Neoplasms 01/2024 - 03/2017
5	Ovarian Neoplasms (Ovarian Cancer) 12/2019 - 02/2002
4	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 01/2008
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/2014 - 05/2008
4	Endometrial Neoplasms (Endometrial Cancer) 09/2010 - 11/2003
3	Lobular Carcinoma 04/2024 - 08/2011
3	Colonic Neoplasms (Colon Cancer) 01/2023 - 01/2016
3	Adenocarcinoma 12/2017 - 12/2010
2	Ewing Sarcoma (Sarcoma, Ewing) 02/2024 - 06/2023
2	Intraductal Papilloma 02/2024 - 04/2023
2	Papilloma (Papillomatosis) 02/2024 - 04/2023
2	Breast Diseases (Breast Disease) 02/2024 - 11/2013

Drug/Important Bio-Agent (IBA)

45	Proteins (Proteins, Gene)FDA Link 04/2024 - 11/2002
37	Biomarkers (Surrogate Marker)IBA 01/2024 - 12/2006
23	Estrogen ReceptorsIBA 12/2023 - 11/2002
22	DNA (Deoxyribonucleic Acid)IBA 05/2024 - 09/2002
18	Progesterone Receptors (Progesterone Receptor)IBA 04/2023 - 11/2002
15	ParaffinIBA 01/2024 - 12/2003
14	Hormones (Hormone)IBA 10/2023 - 01/2012
13	Cadherins (E-Cadherin)IBA 04/2024 - 01/2009
13	Transcription Factors (Transcription Factor)IBA 12/2012 - 03/2003
12	Phenobarbital (Luminal)FDA Link 05/2024 - 03/2012
10	Formaldehyde (Formol)FDA Link 01/2024 - 05/2008
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2017 - 01/2002
10	ErbB Receptors (EGF Receptor)IBA 10/2016 - 11/2002
9	RNA Helicases (RNA Helicase)IBA 02/2024 - 01/2013
9	Cyclin D1IBA 04/2023 - 12/2003
9	Trastuzumab (Herceptin)FDA Link 02/2021 - 01/2009
9	human ERBB2 proteinIBA 02/2021 - 01/2010
8	Estrogen Receptor alphaIBA 05/2024 - 01/2010
8	Messenger RNA (mRNA)IBA 01/2023 - 12/2008
8	Carbonic Anhydrase IXIBA 04/2020 - 01/2005
6	MicroRNAs (MicroRNA)IBA 02/2024 - 10/2015
6	Hematoxylin (Haematoxylon)IBA 12/2017 - 03/2003
5	ChromatinIBA 05/2024 - 01/2005
5	AntibodiesIBA 01/2023 - 11/2002
5	AntigensIBA 01/2023 - 11/2004
5	Eosine Yellowish-(YS) (Eosin)IBA 12/2017 - 04/2011
5	Oxygen (Dioxygen)IBA 12/2012 - 12/2005
5	Cyclin AIBA 08/2007 - 11/2002
4	RNA (Ribonucleic Acid)IBA 01/2023 - 12/2016
4	Tamoxifen FDA LinkGeneric 11/2021 - 01/2014
4	Single-Domain AntibodiesIBA 10/2020 - 04/2006
4	Glucose (Dextrose)FDA LinkGeneric 04/2020 - 01/2002
4	Androgen Receptors (Androgen Receptor)IBA 01/2020 - 05/2012
4	Cisplatin (Platino)FDA LinkGeneric 09/2017 - 02/2004
4	Membrane Proteins (Integral Membrane Proteins)IBA 11/2014 - 06/2012
4	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 06/2012 - 12/2006
3	Immune Checkpoint InhibitorsIBA 01/2024 - 12/2018
3	4-azidobenzylcarazolol (pABC)IBA 10/2023 - 12/2021
3	1-phenyl-3,3-dimethyltriazene (PDT)IBA 10/2020 - 10/2016
3	Hypoxia-Inducible Factor 1IBA 02/2015 - 01/2005
3	Growth Factor ReceptorsIBA 08/2013 - 11/2002
3	Indicators and Reagents (Reagents)IBA 04/2008 - 04/2007
3	Fanconi Anemia Complementation Group D2 ProteinIBA 01/2008 - 10/2003
3	Cell Cycle ProteinsIBA 08/2007 - 01/2004
2	Phosphotransferases (Kinase)IBA 10/2023 - 01/2013
2	Keratin-5 (Keratin 5)IBA 04/2023 - 11/2002
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2023 - 01/2015
2	TabletsIBA 01/2023 - 10/2014
2	IodineIBA 11/2022 - 01/2017
2	Aromatase InhibitorsIBA 11/2021 - 01/2012
2	Estrogens (Estrogen)FDA Link 01/2020 - 04/2004
2	CateninsIBA 01/2019 - 01/2018
2	PlatinumIBA 01/2019 - 01/2005
2	somatostatin receptor 2IBA 12/2018 - 01/2017
2	AntioxidantsIBA 10/2018 - 07/2005
2	Histones (Histone)IBA 10/2018 - 09/2012
2	SteroidsIBA 01/2018 - 08/2017
2	Protons (Proton)IBA 01/2018 - 02/2012
2	Ribonucleases (Ribonuclease)IBA 06/2017 - 01/2013

Therapy/Procedure

55	Therapeutics 02/2024 - 07/2003
24	Ligation 01/2019 - 01/2009
14	Drug Therapy (Chemotherapy) 01/2024 - 02/2004
13	Neoadjuvant Therapy 12/2023 - 05/2007
9	Lymph Node Excision (Lymph Node Dissection) 11/2022 - 08/2003
6	Radiotherapy 03/2022 - 11/2016
6	Adjuvant Chemotherapy 01/2022 - 01/2006
6	Lasers (Laser) 10/2011 - 01/2005
4	Segmental Mastectomy (Lumpectomy) 03/2022 - 07/2013
4	Hysterectomy 12/2019 - 08/2003
3	Photochemotherapy (Photodynamic Therapy) 10/2020 - 10/2016
3	Radiofrequency Ablation 08/2016 - 05/2009
3	Prostatectomy (Retropubic Prostatectomy) 03/2012 - 02/2010
2	Salpingo-oophorectomy 09/2017 - 08/2013
2	Prophylactic Mastectomy 09/2017 - 06/2005