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Hugues de Thé Selected Research

Zidovudine (Retrovir)

8/2013The combination of arsenic, interferon-alpha, and zidovudine restores an "immunocompetent-like" cytokine expression profile in patients with adult T-cell leukemia lymphoma.
6/2009Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL).
7/2006The efficacy of combined therapy of arsenic trioxide and alpha interferon in human T-cell leukemia virus type-1-infected squirrel monkeys (Saimiri sciureus).

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Hugues de Thé Research Topics

Disease

36Neoplasms (Cancer)
12/2023 - 09/2002
33Acute Promyelocytic Leukemia
03/2024 - 06/2003
30Leukemia
03/2024 - 01/2004
12Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
01/2020 - 06/2003
8Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2022 - 10/2005
7Breast Neoplasms (Breast Cancer)
08/2013 - 03/2007
5Infections
01/2022 - 06/2003
3T-Cell Leukemia (Leukemia, T Cell)
06/2007 - 05/2006
3T-Cell Lymphoma (Lymphoma, T Cell)
06/2007 - 11/2004
2Hematologic Neoplasms (Hematological Malignancy)
01/2023 - 06/2011
2Lymphoma (Lymphomas)
01/2020 - 06/2009
2Genetic Translocation (Chromosomal Translocation)
11/2014 - 07/2012
2Carcinoma (Carcinomatosis)
08/2013 - 01/2009
1Congenital Heart Defects (Congenital Heart Defect)
11/2019
1Prostatic Neoplasms (Prostate Cancer)
01/2019
1Listeriosis (Listeria Infection)
10/2017
1Triple Negative Breast Neoplasms
01/2015
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2014
1Skin Neoplasms (Skin Cancer)
09/2013
1Opportunistic Infections (Opportunistic Infection)
08/2013
1Acute Disease
07/2012
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
06/2011
1Carcinogenesis
10/2010
1Sarcoma (Soft Tissue Sarcoma)
10/2010
1Pathologic Complete Response
01/2010
1Squamous Cell Carcinoma of Head and Neck
02/2009
1Bronchiolitis Obliterans Syndrome
02/2009
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2009
1Inflammation (Inflammations)
02/2009
1Nijmegen Breakage Syndrome
06/2008
1Ataxia Telangiectasia (Louis Bar Syndrome)
06/2008
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
06/2007

Drug/Important Bio-Agent (IBA)

25Proteins (Proteins, Gene)FDA Link
10/2022 - 10/2003
16Tretinoin (Retinoic Acid)FDA LinkGeneric
03/2024 - 06/2003
13ArsenicIBA
03/2024 - 01/2004
12Arsenic Trioxide (Trisenox)FDA Link
01/2021 - 09/2002
10Oncogene Proteins (Oncogene Protein)IBA
03/2024 - 05/2006
8Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
03/2024 - 06/2011
5RetinoidsIBA
01/2021 - 10/2005
4Estrogen ReceptorsIBA
01/2015 - 01/2010
4Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
12/2014 - 07/2011
4Interferon-alpha (Interferon Alfa)IBA
08/2013 - 01/2004
4Cyclophosphamide (Cytoxan)FDA LinkGeneric
08/2013 - 03/2007
3InterferonsIBA
01/2021 - 01/2014
3Histone Deacetylase InhibitorsIBA
01/2018 - 04/2014
3CytokinesIBA
01/2018 - 08/2013
3Retinoic Acid Receptor alphaIBA
11/2014 - 10/2005
3Zidovudine (Retrovir)FDA LinkGeneric
08/2013 - 07/2006
3Phenobarbital (Luminal)FDA Link
08/2013 - 01/2009
2Androgen Receptors (Androgen Receptor)IBA
01/2019 - 05/2013
2LigandsIBA
01/2019 - 10/2005
2UbiquitinIBA
01/2018 - 07/2004
2Hormones (Hormone)IBA
01/2018 - 01/2015
2Histones (Histone)IBA
01/2015 - 06/2008
2Oxidants (Oxidizing Agents)IBA
01/2014 - 07/2010
2Messenger RNA (mRNA)IBA
05/2013 - 10/2010
2Therapeutic UsesIBA
02/2013 - 06/2011
2Phosphotransferases (Kinase)IBA
07/2011 - 07/2006
2Proteasome Endopeptidase Complex (Proteasome)IBA
07/2011 - 07/2004
2Aligeron (AS 2)IBA
07/2010 - 07/2006
2Epirubicin (Ellence)FDA LinkGeneric
02/2009 - 03/2007
1Serine (L-Serine)FDA Link
10/2022
1Phenylalanine (L-Phenylalanine)FDA Link
10/2022
1Viral ProteinsIBA
01/2022
1Histone Deacetylases (Histone Deacetylase)IBA
01/2022
1Cystine (L-Cystine)IBA
01/2022
1OTX015IBA
11/2021
1proto-oncogene protein Spi-1IBA
01/2019
1AndrogensIBA
01/2019
1Promyelocytic Leukemia ProteinIBA
10/2017
1Listeria monocytogenes hlyA protein (listeriolysin O)IBA
10/2017
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
01/2017
1Trans-Activators (Trans-Acting Factor)IBA
01/2015
1abexinostatIBA
01/2015
1Estrogen Receptor alphaIBA
01/2015
1Codon (Codons)IBA
09/2013
1Doxorubicin (Adriamycin)FDA LinkGeneric
08/2013
18-((4-chlorophenyl)thio)cyclic-3',5'-AMPIBA
02/2013
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
02/2013
1Transcription Factors (Transcription Factor)IBA
07/2011
1TamoxifenFDA LinkGeneric
04/2011
1Drug CombinationsIBA
12/2010
1AnthracyclinesIBA
01/2010
1Alkylating AgentsIBA
01/2010
12- morpholin- 4- yl- 6- thianthren- 1- yl- pyran- 4- oneIBA
06/2008
1DNA (Deoxyribonucleic Acid)IBA
01/2008
1Tumor Suppressor Protein p53IBA
01/2008
1cellular retinoic acid binding protein IIBA
11/2007
1CeramidesIBA
06/2007
1ceramide glucosyltransferaseIBA
06/2007
1Tacrolimus (Prograf)FDA LinkGeneric
06/2007
1CalcineurinIBA
06/2007

Therapy/Procedure

27Therapeutics
03/2024 - 11/2004
16Drug Therapy (Chemotherapy)
12/2015 - 06/2003
2Lasers (Laser)
09/2013 - 02/2009
2Homologous Transplantation
09/2013 - 02/2009
1Castration
01/2019
1Aftercare (After-Treatment)
08/2013
1Chinese Traditional Medicine (Traditional Chinese Medicine)
04/2010
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
02/2009