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Yvonne de Jong Selected Research

Drug Therapy (Chemotherapy)

9/2018Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma.
10/2016Inhibition of Bcl-2 family members sensitizes mesenchymal chondrosarcoma to conventional chemotherapy: report on a novel mesenchymal chondrosarcoma cell line.
1/2016Molecular oncogenesis of chondrosarcoma: impact for targeted treatment.
11/2015Pharmacological inhibition of Bcl-xL sensitizes osteosarcoma to doxorubicin.

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Yvonne de Jong Research Topics

Disease

8Chondrosarcoma
12/2019 - 01/2016
7Neoplasms (Cancer)
01/2022 - 08/2017
2Hypersensitivity (Allergy)
01/2023 - 01/2022
2Squamous Cell Carcinoma of Head and Neck
01/2023 - 01/2022
2Osteosarcoma (Osteogenic Sarcoma)
11/2015 - 11/2015
1Ataxia Telangiectasia (Louis Bar Syndrome)
12/2019
1Leukemia
12/2019
1Glioma (Gliomas)
12/2019
1Hypoxia (Hypoxemia)
04/2019
1Myxoid Liposarcoma
08/2017
1Mesenchymal Chondrosarcoma
10/2016

Drug/Important Bio-Agent (IBA)

3Small Interfering RNA (siRNA)IBA
01/2023 - 11/2015
2Cisplatin (Platino)FDA LinkGeneric
01/2023 - 09/2018
2Messenger RNA (mRNA)IBA
01/2022 - 11/2015
2Phosphotransferases (Kinase)IBA
12/2019 - 11/2015
2NAD (NADH)IBA
04/2019 - 12/2017
2SurvivinIBA
01/2019 - 08/2017
2ABT-737IBA
09/2018 - 10/2016
2Doxorubicin (Adriamycin)FDA LinkGeneric
09/2018 - 11/2015
1EmetineIBA
01/2023
1N,N'- (2,2'- (hexa- 2,4- diyne- 1,6- diylbis(oxy))bis(2,3- dihydro- 1H- indene- 2,1- diyl))bis(1- (2- cyclohexyl- 2- (2- (methylamino)propanamido)acetyl)pyrrolidine- 2- carboxamide)IBA
01/2022
1Temozolomide (Temodar)FDA LinkGeneric
12/2019
1Poly(ADP-ribose) Polymerase InhibitorsIBA
12/2019
1talazoparibIBA
12/2019
1alpha-hydroxyglutarateIBA
12/2019
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
12/2019
1MethyltransferasesIBA
12/2019
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2019
1Aurora Kinase AIBA
12/2019
1BI 6727IBA
12/2019
14- (3- chloro- 2- fluorophenoxy)- 1- ((6- (1,3- thiazol- 2- ylamino)pyridin to 2-yl)methyl) cyclohexanecarboxylic acidIBA
12/2019
1LY2603618IBA
12/2019
1RNA (Ribonucleic Acid)IBA
12/2019
1Glutamine (L-Glutamine)FDA Link
04/2019
1Mechanistic Target of Rapamycin Complex 2IBA
04/2019
1Mechanistic Target of Rapamycin Complex 1IBA
04/2019
1sapanisertibIBA
04/2019
1Sirolimus (Rapamycin)FDA Link
04/2019
1Glutathione (Reduced Glutathione)IBA
04/2019
1AGI-5198IBA
01/2019
1Biomarkers (Surrogate Marker)IBA
01/2019
1Caspase 3 (Caspase-3)IBA
09/2018
1S55746IBA
09/2018
1CB-839IBA
01/2018
1Phenformin (Fenformin)IBA
01/2018
1GlutaminaseIBA
01/2018
1Metformin (Glucophage)FDA LinkGeneric
01/2018
1Chloroquine (Aralen)FDA LinkGeneric
01/2018
1CollagenIBA
12/2017
1isocitric acid (isocitrate)IBA
12/2017
1WEHI-539IBA
11/2015
1Proteins (Proteins, Gene)FDA Link
11/2015
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
11/2015

Therapy/Procedure

5Radiotherapy
01/2022 - 01/2016
4Drug Therapy (Chemotherapy)
09/2018 - 11/2015
2Therapeutics
01/2023 - 11/2015
1Aftercare (After-Treatment)
12/2019