Aline de Conti Selected Research

Non-alcoholic Fatty Liver Disease

11/2022	Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice.
1/2020	Characterization of the variability in the extent of nonalcoholic fatty liver induced by a high-fat diet in the genetically diverse Collaborative Cross mouse model.
1/2019	Gene Expression and DNA Methylation Alterations in the Glycine N-Methyltransferase Gene in Diet-Induced Nonalcoholic Fatty Liver Disease-Associated Carcinogenesis.
1/2018	Epigenetically mediated inhibition of S-adenosylhomocysteine hydrolase and the associated dysregulation of 1-carbon metabolism in nonalcoholic steatohepatitis and hepatocellular carcinoma.
10/2017	MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis.
1/2017	Inhibition of the Cell Death Pathway in Nonalcoholic Steatohepatitis (NASH)-Related Hepatocarcinogenesis Is Associated with Histone H4 lysine 16 Deacetylation.
11/2014	Genotoxic, epigenetic, and transcriptomic effects of tamoxifen in mouse liver.
7/2014	Effect of methionine-deficient and methionine-supplemented diets on the hepatic one-carbon and lipid metabolism in mice.
6/2013	Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury.
11/2012	Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism.

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Aline de Conti Research Topics

Disease

14	Carcinogenesis 12/2020 - 07/2014
10	Neoplasms (Cancer) 11/2022 - 12/2012
10	Non-alcoholic Fatty Liver Disease 11/2022 - 11/2012
6	Body Weight (Weight, Body) 11/2017 - 06/2006
4	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 11/2012
3	Liver Neoplasms (Liver Cancer) 04/2016 - 07/2007
1	Liver Diseases (Liver Disease) 11/2022
1	Fatty Liver 01/2020
1	Insulin Resistance 01/2020
1	Alcoholic Fatty Liver 01/2018
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2017
1	Breast Neoplasms (Breast Cancer) 11/2014
1	Autistic Disorder (Autism) 01/2014

Drug/Important Bio-Agent (IBA)

6	Folic Acid (Vitamin M)FDA LinkGeneric 11/2022 - 11/2012
5	Choline (Choline Chloride)IBA 11/2022 - 11/2012
4	LipidsIBA 11/2022 - 11/2012
4	Histones (Histone)IBA 01/2019 - 12/2016
4	furanIBA 03/2017 - 04/2015
3	Lysine (L-Lysine)FDA Link 01/2019 - 12/2016
3	CarcinogensIBA 01/2019 - 12/2016
3	tributyrinIBA 04/2016 - 07/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 11/2022 - 01/2020
2	Butyrates (Butyrate)IBA 12/2020 - 02/2016
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 12/2016
2	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 01/2014
2	MethapyrileneIBA 11/2017 - 01/2017
2	MicroRNAs (MicroRNA)IBA 10/2017 - 12/2016
2	Proteins (Proteins, Gene)FDA Link 12/2016 - 04/2016
2	CarbonIBA 07/2014 - 06/2013
1	CDAA (Randox)IBA 11/2022
1	Amino Acids FDA Link 11/2022
1	Nonesterified Fatty Acids (NEFA)IBA 11/2022
1	CholesterolIBA 01/2020
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	Sucrose (Saccharose)IBA 01/2020
1	HDL LipoproteinsIBA 01/2020
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2020
1	Glycine N-Methyltransferase (Glycine Sarcosine N-Methyltransferase)IBA 01/2019
1	1,3-butadiene (divinyl)IBA 01/2019
1	Drinking WaterIBA 01/2019
1	CytosineIBA 01/2019
1	ChromatinIBA 01/2018
1	HomocysteineIBA 01/2018
1	AdenosylhomocysteinaseIBA 01/2018
1	TransposasesIBA 01/2018
1	ApoferritinsIBA 11/2017
1	IronIBA 11/2017
1	Transferrin (beta 2 Transferrin)IBA 11/2017
1	Indicators and Reagents (Reagents)IBA 10/2017
1	Ethanol (Ethyl Alcohol)IBA 01/2017
1	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2017
1	PPAR alphaIBA 01/2017
1	Nucleosomes (Nucleosome)IBA 12/2016
1	Butyric Acid (Butanoic Acid)IBA 04/2016
1	Exportin 1 ProteinIBA 04/2016
1	Linseed Oil (Flaxseed Oil)IBA 02/2016
1	Transferrin Receptors (Transferrin Receptor)IBA 01/2016
1	LipocalinsIBA 11/2014
1	Tamoxifen FDA LinkGeneric 11/2014
1	Methionine (L-Methionine)FDA Link 07/2014
1	5-hydroxymethylcytosineIBA 01/2014
1	NF-kappa B (NF-kB)IBA 01/2014
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2014
1	5-Methylcytosine (5 Methylcytosine)IBA 01/2014
1	8-Hydroxy-2'-DeoxyguanosineIBA 01/2014
1	Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA 06/2013
1	homocysteinaseIBA 06/2013
1	Methionine AdenosyltransferaseIBA 06/2013
1	CystathionineIBA 06/2013
1	Methylenetetrahydrofolate Dehydrogenase (NADP) (Dehydrogenase, Methylenetetrahydrofolate)IBA 06/2013
1	LuteinIBA 07/2007
1	Corn Oil (Oil, Corn)IBA 06/2006

Therapy/Procedure

2	Chemoprevention 11/2012 - 07/2007
1	Therapeutics 12/2012