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Yuan Zhou Selected Research

Ovarian Neoplasms (Ovarian Cancer)

9/2022And-1 Coordinates with the FANCM Complex to Regulate Fanconi Anemia Signaling and Cisplatin Resistance.
12/2021Discovery and characterization of potent And-1 inhibitors for cancer treatment.
12/2021Identification of potent SENP1 inhibitors that inactivate SENP1/JAK2/STAT signaling pathway and overcome platinum drug resistance in ovarian cancer.
1/2021p85β alters response to EGFR inhibitor in ovarian cancer through p38 MAPK-mediated regulation of DNA repair.
1/2020p85β regulates autophagic degradation of AXL to activate oncogenic signaling.
10/2019ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer.
7/2005Proteomic analysis of a preneoplastic phenotype in ovarian surface epithelial cells derived from prophylactic oophorectomies.

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Yuan Zhou Research Topics

Disease

166Neoplasms (Cancer)
04/2024 - 06/2005
41Infections
12/2023 - 03/2009
36Hepatocellular Carcinoma (Hepatoma)
03/2024 - 11/2005
35Inflammation (Inflammations)
04/2024 - 05/2003
28Neoplasm Metastasis (Metastasis)
03/2024 - 11/2006
21Pain (Aches)
01/2024 - 10/2013
16Stomach Neoplasms (Stomach Cancer)
12/2024 - 06/2007
16Colorectal Neoplasms (Colorectal Cancer)
02/2024 - 10/2015
16Alzheimer Disease (Alzheimer's Disease)
01/2024 - 06/2007
16Carcinogenesis
12/2022 - 06/2007
15Neuralgia (Stump Neuralgia)
07/2023 - 10/2013
13Fibrosis (Cirrhosis)
05/2024 - 01/2018
13Cardiovascular Diseases (Cardiovascular Disease)
11/2023 - 01/2011
13Traumatic Brain Injuries (Traumatic Brain Injury)
01/2023 - 12/2013
11Hyperalgesia
12/2023 - 10/2013
11Cognitive Dysfunction
05/2023 - 03/2007
11Leukemia
11/2022 - 04/2006
11Hypoxia (Hypoxemia)
04/2022 - 06/2008
10Psoriasis (Pustulosis Palmaris et Plantaris)
10/2023 - 01/2020
10Carcinoma (Carcinomatosis)
01/2023 - 07/2005
9Chronic Pain
12/2023 - 01/2016
9Schizophrenia (Dementia Praecox)
12/2023 - 03/2007
9Breast Neoplasms (Breast Cancer)
01/2023 - 09/2008
8Glioma (Gliomas)
01/2024 - 02/2010
8Neuroinflammatory Diseases
12/2023 - 01/2020
7Dermatitis
01/2024 - 01/2021
7Liver Neoplasms (Liver Cancer)
11/2023 - 01/2019
7COVID-19
10/2023 - 01/2020
7Hypersensitivity (Allergy)
07/2023 - 01/2014
7Obesity
05/2023 - 01/2017
7Body Weight (Weight, Body)
02/2023 - 06/2011
7Ovarian Neoplasms (Ovarian Cancer)
09/2022 - 07/2005
6Insulin Resistance
02/2024 - 10/2008
6Major Depressive Disorder (Major Depressive Disorders)
01/2024 - 12/2021
6Stroke (Strokes)
01/2024 - 10/2010
6Hypertension (High Blood Pressure)
11/2023 - 01/2011
6Necrosis
10/2023 - 01/2011
6Pancreatic Neoplasms (Pancreatic Cancer)
04/2023 - 01/2018
6Adenocarcinoma
03/2023 - 06/2007
6Hemorrhage
01/2023 - 06/2015
6Myocardial Infarction
01/2023 - 05/2010
6Multiple Sclerosis
01/2023 - 12/2013
6Lung Neoplasms (Lung Cancer)
12/2022 - 05/2013
6Ischemia
01/2022 - 09/2004
6Glioblastoma (Glioblastoma Multiforme)
01/2022 - 08/2013
6Lymphatic Metastasis
12/2018 - 11/2013
5Rectal Neoplasms (Rectal Cancer)
02/2024 - 01/2019
5Mitochondrial Diseases (Mitochondrial Disease)
02/2024 - 01/2018
5Type 2 Diabetes Mellitus (MODY)
01/2024 - 01/2018
5Coronary Artery Disease (Coronary Atherosclerosis)
01/2024 - 01/2011
5Atopic Dermatitis (Atopic Eczema)
12/2023 - 01/2018
5Sepsis (Septicemia)
11/2023 - 05/2018
5Reperfusion Injury
02/2023 - 01/2018
5Thrombosis (Thrombus)
01/2023 - 10/2010

Drug/Important Bio-Agent (IBA)

94Proteins (Proteins, Gene)FDA Link
03/2024 - 07/2005
39Biomarkers (Surrogate Marker)IBA
06/2023 - 05/2003
23MicroRNAs (MicroRNA)IBA
01/2024 - 06/2012
22CytokinesIBA
12/2023 - 06/2007
17Messenger RNA (mRNA)IBA
03/2024 - 01/2012
15EnzymesIBA
03/2024 - 04/2008
15Therapeutic UsesIBA
12/2022 - 08/2005
14RNA (Ribonucleic Acid)IBA
04/2024 - 07/2013
11DNA (Deoxyribonucleic Acid)IBA
11/2023 - 01/2013
10Antiviral Agents (Antivirals)IBA
01/2023 - 01/2019
10Transcription Factors (Transcription Factor)IBA
01/2023 - 01/2013
9Indicators and Reagents (Reagents)IBA
04/2024 - 04/2012
9Neuroprotective AgentsIBA
12/2023 - 05/2010
9Long Noncoding RNAIBA
09/2023 - 01/2019
8Cadherins (E-Cadherin)IBA
04/2024 - 02/2016
8LipidsIBA
06/2023 - 01/2019
8Doxorubicin (Adriamycin)FDA LinkGeneric
01/2023 - 04/2006
8Caspase 3 (Caspase-3)IBA
12/2022 - 03/2007
7Cisplatin (Platino)FDA LinkGeneric
01/2024 - 05/2010
7LipopolysaccharidesIBA
01/2023 - 12/2011
7Phosphotransferases (Kinase)IBA
01/2023 - 06/2013
7Small Interfering RNA (siRNA)IBA
01/2023 - 04/2016
6Reactive Oxygen Species (Oxygen Radicals)IBA
01/2024 - 01/2018
6VaccinesIBA
11/2023 - 01/2019
6Glucose (Dextrose)FDA LinkGeneric
02/2023 - 09/2014
6Interleukin-17 (Interleukin 17)IBA
10/2022 - 06/2007
6Immunoglobulin G (IgG)IBA
01/2022 - 04/2008
6zhen-wu-tangIBA
01/2021 - 04/2016
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2020 - 09/2004
6Mitochondrial DNA (mtDNA)IBA
01/2016 - 01/2012
5Analgesics (Analgesic Drugs)IBA
12/2023 - 01/2022
5Peptides (Polypeptides)IBA
11/2023 - 09/2011
5Calcium Channels (Calcium Channel)IBA
11/2023 - 01/2018
5Imiquimod (Aldara)FDA LinkGeneric
10/2023 - 10/2022
5InterferonsIBA
09/2023 - 01/2017
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2023 - 08/2014
56-methyladenineIBA
07/2023 - 01/2021

Therapy/Procedure

69Therapeutics
04/2024 - 02/2008
29Drug Therapy (Chemotherapy)
02/2024 - 04/2006
10Radiotherapy
11/2023 - 12/2018
9Immunotherapy
04/2024 - 02/2008
8Transplantation
05/2024 - 06/2008
7Ligation
01/2024 - 05/2018
7Chinese Traditional Medicine (Traditional Chinese Medicine)
12/2023 - 03/2014
7Neoadjuvant Therapy
12/2022 - 01/2018
5Length of Stay
04/2024 - 05/2017