Yubin Zhang Selected Research

Inflammasomes

12/2023	Demethyleneberberine alleviates Pseudomonas aeruginosa-induced acute pneumonia by inhibiting the AIM2 inflammasome and oxidative stress.
9/2021	Demethylenetetrahydroberberine alleviates nonalcoholic fatty liver disease by inhibiting the NLRP3 inflammasome and oxidative stress in mice.

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Yubin Zhang Research Topics

Disease

14	Inflammation (Inflammations) 01/2023 - 02/2011
12	Neoplasms (Cancer) 02/2024 - 06/2004
7	Obesity 01/2023 - 01/2013
6	Fibrosis (Cirrhosis) 01/2024 - 06/2016
4	Body Weight (Weight, Body) 09/2021 - 04/2016
4	Cardiomegaly (Heart Hypertrophy) 03/2019 - 12/2017
3	Infections 12/2023 - 07/2015
3	Pneumonia (Pneumonitis) 12/2023 - 12/2022
3	Colitis 01/2023 - 09/2016
3	Ulcerative Colitis 12/2022 - 03/2020
3	Neuroinflammatory Diseases 10/2020 - 10/2012
3	Hypoxia (Hypoxemia) 10/2020 - 01/2015
3	Hypertension (High Blood Pressure) 01/2020 - 12/2017
3	Hypertrophy 01/2019 - 12/2017
2	Atherosclerosis 04/2024 - 11/2017
2	Thalassemia 01/2023 - 01/2022
2	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 01/2023 - 01/2022
2	Type 2 Diabetes Mellitus (MODY) 11/2022 - 01/2020
2	Non-alcoholic Fatty Liver Disease 09/2021 - 04/2016
2	Insulin Resistance 01/2020 - 12/2017
2	Wounds and Injuries (Trauma) 10/2018 - 03/2018
2	Adenocarcinoma 05/2018 - 06/2004
2	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2015 - 12/2014
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 02/2024
1	Infarction (Infarctions) 02/2024
1	Bites and Stings (Sting) 01/2024
1	Cardiotoxicity 01/2024
1	Acute Lung Injury 12/2023
1	Fever of Unknown Origin 07/2023
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 01/2023
1	Bundle-Branch Block (Fascicular Block) 01/2023
1	Heart Failure 01/2023
1	Atrial Fibrillation 01/2023
1	Cardiac Arrhythmias (Arrythmia) 01/2023
1	Splenomegaly 10/2022
1	Myocardial Infarction 01/2022

Drug/Important Bio-Agent (IBA)

7	LipidsIBA 04/2024 - 04/2016
7	demethyleneberberineIBA 02/2024 - 01/2015
6	Interleukin-6 (Interleukin 6)IBA 12/2022 - 12/2017
4	AntioxidantsIBA 02/2024 - 01/2015
4	Proteins (Proteins, Gene)FDA Link 01/2024 - 08/2006
3	BerberineIBA 01/2023 - 12/2014
3	Glucose (Dextrose)FDA LinkGeneric 12/2022 - 12/2019
3	gegenqinlianIBA 04/2021 - 09/2016
3	HerbicidesIBA 10/2020 - 03/2018
3	Transcription Factors (Transcription Factor)IBA 10/2020 - 01/2019
3	Angiotensin IIIBA 01/2019 - 12/2017
3	Histone Deacetylase InhibitorsIBA 08/2006 - 06/2004
3	romidepsin (FK228)FDA Link 08/2006 - 06/2004
2	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 03/2017
2	NLR ProteinsIBA 04/2024 - 12/2022
2	CollagenIBA 02/2024 - 09/2021
2	Anti-Bacterial Agents (Antibiotics)IBA 12/2023 - 07/2023
2	InflammasomesIBA 12/2023 - 09/2021
2	IronIBA 01/2023 - 01/2022
2	SaltsIBA 12/2022 - 01/2018
2	Drinking WaterIBA 10/2022 - 02/2011
2	Choline (Choline Chloride)IBA 09/2021 - 04/2016
2	Alanine Transaminase (SGPT)IBA 09/2021 - 01/2018
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 09/2021 - 01/2018
2	Methionine (L-Methionine)FDA Link 09/2021 - 04/2016
2	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 09/2021 - 01/2015
2	ParaquatIBA 10/2020 - 09/2020
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2019 - 01/2019
2	Therapeutic UsesIBA 01/2019 - 11/2017
2	Interferon Type IIBA 01/2018 - 04/2014
2	CytokinesIBA 11/2017 - 10/2012
2	AMP-Activated Protein KinasesIBA 04/2016 - 01/2015
2	Fatty Acids (Saturated Fatty Acids)IBA 04/2016 - 01/2015
2	AcidsIBA 07/2006 - 06/2004
1	Bleomycin (Blenoxane)FDA LinkGeneric 02/2024
1	Biotin (Vitamin H)FDA Link 02/2024
1	AvidinIBA 02/2024
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2024
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023
1	Nucleic AcidsIBA 07/2023
1	Amino Acids FDA Link 01/2023
1	VitaminsIBA 01/2023
1	Vehicle Emissions (Emissions, Vehicle)IBA 01/2023
1	Trinitrobenzenesulfonic AcidIBA 01/2023
1	Granzymes (Granzyme)IBA 01/2023
1	PNU-282987IBA 01/2023
1	1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA 01/2023
1	CurcuminIBA 01/2023
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 12/2022
1	Messenger RNA (mRNA)IBA 12/2022
1	Dextran SulfateIBA 12/2022
1	Toll-Like Receptor 4IBA 12/2022
1	Metformin (Glucophage)FDA LinkGeneric 11/2022
1	SirtuinsIBA 11/2022
1	Janus KinasesIBA 10/2022
1	InterferonsIBA 10/2022

Therapy/Procedure

10	Therapeutics 01/2023 - 07/2005
2	Drug Therapy (Chemotherapy) 01/2024 - 05/2018
1	Catheter Ablation 01/2023
1	Ketogenic Diet 01/2023
1	Vagotomy 01/2023
1	Cardiac Resynchronization Therapy Devices 01/2023
1	Cardiac Resynchronization Therapy 01/2023
1	Diet Therapy (Therapy, Diet) 01/2023