Liangren Zhang Selected Research

Glycogen Synthase (Synthase I)

6/2019	Discovery of novel glycogen synthase kinase-3α inhibitors: Structure-based virtual screening, preliminary SAR and biological evaluation for treatment of acute myeloid leukemia.
1/2018	Discovery of new GSK-3β inhibitors through structure-based virtual screening.

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Liangren Zhang Research Topics

Disease

24	Neoplasms (Cancer) 08/2023 - 12/2009
4	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2022 - 02/2015
3	Inflammation (Inflammations) 12/2020 - 01/2018
3	Schizophrenia (Dementia Praecox) 11/2019 - 06/2016
2	Virus Diseases (Viral Diseases) 11/2023 - 05/2022
2	Weight Gain 11/2023 - 11/2018
2	Carcinogenesis 08/2023 - 10/2020
2	Pain (Aches) 07/2022 - 07/2021
2	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 02/2011
2	Infections 12/2020 - 01/2018
2	Cardiovascular Diseases (Cardiovascular Disease) 09/2020 - 09/2011
2	Melanoma (Melanoma, Malignant) 07/2018 - 01/2016
2	Human Influenza (Influenza) 03/2016 - 09/2013
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2024
1	Hepatocellular Carcinoma (Hepatoma) 03/2024
1	Metabolic Diseases (Metabolic Disease) 03/2024
1	Gout 01/2023
1	Chronic Pain 07/2022
1	Ataxia Telangiectasia (Louis Bar Syndrome) 04/2022
1	Colonic Neoplasms (Colon Cancer) 01/2022
1	Hyperalgesia 07/2021
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 10/2020
1	Non-alcoholic Fatty Liver Disease 01/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 06/2019
1	Pathologic Processes 01/2019
1	Major Depressive Disorder (Major Depressive Disorders) 04/2018
1	Breast Neoplasms (Breast Cancer) 03/2018
1	Triple Negative Breast Neoplasms 03/2018
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2017
1	Rupture 01/2017
1	Hemorrhagic Stroke 01/2017
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2017
1	Hemorrhage 01/2017

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 08/2023 - 09/2013
4	LigandsIBA 07/2023 - 09/2013
3	snake venom protein C activatorIBA 02/2023 - 05/2022
3	Analgesics (Analgesic Drugs)IBA 01/2023 - 07/2021
3	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022 - 12/2009
3	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 12/2020 - 06/2016
2	ProlactinIBA 11/2023 - 11/2018
2	Phospholipid Hydroperoxide Glutathione PeroxidaseIBA 06/2023 - 02/2023
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2023 - 06/2021
2	Formaldehyde (Formol)FDA Link 07/2022 - 07/2021
2	AcidsIBA 07/2022 - 03/2016
2	Phosphotransferases (Kinase)IBA 05/2022 - 04/2022
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 04/2022 - 07/2018
2	Mitogen-Activated Protein Kinase 10IBA 09/2020 - 01/2019
2	Glycogen Synthase (Synthase I)IBA 06/2019 - 01/2018
2	Hemagglutinins (Hemagglutinin)IBA 03/2016 - 09/2013
1	oxidized low density lipoproteinIBA 03/2024
1	CholesterolIBA 03/2024
1	LipidsIBA 03/2024
1	LDL CholesterolIBA 03/2024
1	CalciumIBA 11/2023
1	CarbonIBA 07/2023
1	Proteolysis Targeting ChimeraIBA 07/2023
1	Lenalidomide (CC 5013)FDA Link 07/2023
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 02/2023
1	coumarinIBA 01/2023
1	Uric Acid (Urate)IBA 01/2023
1	Freund's AdjuvantIBA 07/2022
1	Capsaicin (Zostrix)FDA Link 07/2022
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 05/2022
1	DNA (Deoxyribonucleic Acid)IBA 04/2022
1	Proteasome InhibitorsIBA 01/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022
1	nitazoxanide (NTZ)FDA Link 01/2022
1	Carrier Proteins (Binding Protein)IBA 01/2021
1	CCR2 ReceptorsIBA 01/2021
1	vacuolin-1IBA 01/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2020
1	Oncogene Proteins (Oncogene Protein)IBA 10/2020
1	AminesIBA 10/2020
1	Antineoplastic Agents (Antineoplastics)IBA 10/2020
1	Bile Acids and Salts (Bile Acids)IBA 01/2020
1	NAD (NADH)IBA 10/2019
1	Glycogen Synthase KinasesIBA 06/2019
1	Protein Isoforms (Isoforms)IBA 01/2019
1	indolin-2-oneIBA 01/2019
1	Cyclic ADP-Ribose (cADPR)IBA 01/2019
1	Antipsychotic Agents (Antipsychotics)IBA 11/2018
1	Risperidone (Risperdal Consta)FDA LinkGeneric 11/2018
1	Small Interfering RNA (siRNA)IBA 07/2018
1	Phosphatidylinositols (Phosphatidylinositol)IBA 07/2018
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 04/2018
1	Estrogen ReceptorsIBA 03/2018
1	Progesterone Receptors (Progesterone Receptor)IBA 03/2018
1	BenzenesulfonamidesIBA 03/2018
1	human ERBB2 proteinIBA 03/2018
1	furanIBA 03/2018
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2018
1	Chemokine ReceptorsIBA 01/2018
1	Urea (Carbamide)FDA LinkGeneric 03/2017
1	pyridazineIBA 03/2017
1	Miconazole (Monistat)FDA LinkGeneric 01/2017

Therapy/Procedure

6	Therapeutics 08/2023 - 07/2018
1	Drug Therapy (Chemotherapy) 04/2022
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2020
1	Immunotherapy 01/2018