Jianmin Zhang Selected Research

Severe Acute Respiratory Syndrome

10/2008	Aryl methylene ketones and fluorinated methylene ketones as reversible inhibitors for severe acute respiratory syndrome (SARS) 3C-like proteinase.
5/2008	Heteroaromatic ester inhibitors of hepatitis A virus 3C proteinase: Evaluation of mode of action.
1/2008	Molecular docking identifies the binding of 3-chloropyridine moieties specifically to the S1 pocket of SARS-CoV Mpro.
4/2007	Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters.
12/2004	Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro.

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Jianmin Zhang Research Topics

Disease

65	Neoplasms (Cancer) 05/2024 - 07/2004
32	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 05/2024 - 08/2012
32	Brain Injuries (Brain Injury) 12/2023 - 12/2013
24	Glioma (Gliomas) 02/2024 - 07/2013
22	Stroke (Strokes) 12/2023 - 01/2013
21	Inflammation (Inflammations) 03/2024 - 09/2005
17	Brain Edema (Cerebral Edema) 12/2023 - 10/2013
15	Ischemic Stroke 01/2023 - 12/2014
12	Carcinogenesis 02/2024 - 07/2004
12	Cerebral Hemorrhage 02/2023 - 01/2018
10	Neoplasm Metastasis (Metastasis) 05/2024 - 12/2010
10	Infections 05/2024 - 06/2004
10	Neuroinflammatory Diseases 10/2023 - 10/2013
9	Breast Neoplasms (Breast Cancer) 02/2023 - 07/2004
9	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2018 - 09/2007
7	Conversion Disorder (Astasia Abasia) 11/2023 - 08/2019
6	Hematoma 02/2023 - 10/2017
6	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 09/2015
5	Stomach Neoplasms (Stomach Cancer) 05/2024 - 11/2017
5	Colorectal Neoplasms (Colorectal Cancer) 08/2023 - 08/2015
5	Wounds and Injuries (Trauma) 01/2020 - 08/2012
5	Severe Acute Respiratory Syndrome 10/2008 - 12/2004
4	Glioblastoma (Glioblastoma Multiforme) 02/2024 - 01/2021
4	Brain Neoplasms (Brain Tumor) 01/2023 - 01/2014
4	Epilepsy (Aura) 01/2023 - 09/2014
4	Brain Ischemia (Cerebral Ischemia) 01/2023 - 04/2009
4	Parkinson Disease (Parkinson's Disease) 01/2023 - 01/2016
4	Pain (Aches) 01/2022 - 01/2020
4	Meningioma (Meningiomas) 01/2022 - 01/2020
4	Hyperglycemia 10/2021 - 01/2018
4	Hemorrhage 01/2021 - 11/2010
3	Autoimmune Diseases (Autoimmune Disease) 05/2024 - 01/2016
3	Atherosclerosis 03/2024 - 01/2012
3	Cerebrovascular Disorders (Cerebrovascular Occlusion) 03/2024 - 09/2017
3	Nausea 02/2024 - 01/2020
3	Vomiting 02/2024 - 01/2020
3	Ischemia 12/2023 - 09/2016
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2023 - 01/2021
3	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 09/2013
3	Rupture 01/2022 - 03/2015
3	Edema (Dropsy) 01/2022 - 10/2020
3	Mitochondrial Diseases (Mitochondrial Disease) 10/2021 - 01/2018
3	Optic Nerve Injuries 04/2021 - 07/2020
3	Genomic Instability 01/2021 - 07/2004
3	Central Nervous System Diseases (CNS Diseases) 01/2021 - 01/2016

Drug/Important Bio-Agent (IBA)

33	Proteins (Proteins, Gene)FDA Link 02/2024 - 02/2002
19	Neuroprotective AgentsIBA 07/2023 - 08/2012
17	Biomarkers (Surrogate Marker)IBA 02/2023 - 11/2013
10	InflammasomesIBA 04/2024 - 10/2013
9	CytokinesIBA 05/2024 - 09/2005
9	RNA (Ribonucleic Acid)IBA 12/2023 - 12/2014
9	MicroRNAs (MicroRNA)IBA 06/2023 - 12/2018
9	MelatoninIBA 12/2022 - 01/2016
8	Phosphotransferases (Kinase)IBA 02/2021 - 02/2006
7	Long Noncoding RNAIBA 12/2023 - 01/2016
6	LigandsIBA 08/2023 - 01/2018
6	Peptide Hydrolases (Proteases)FDA Link 10/2008 - 12/2004
5	LipidsIBA 03/2024 - 01/2017
5	AntioxidantsIBA 01/2023 - 12/2020
4	ChemokinesIBA 05/2024 - 07/2022
4	Interleukin-6 (Interleukin 6)IBA 05/2024 - 01/2016
4	OsteopontinIBA 12/2023 - 01/2015
4	Therapeutic UsesIBA 10/2023 - 01/2019
4	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2023 - 01/2021
4	Hormones (Hormone)IBA 01/2023 - 12/2016
4	IronIBA 01/2023 - 01/2017
4	Transcription Factors (Transcription Factor)IBA 01/2023 - 05/2009
4	Small Interfering RNA (siRNA)IBA 11/2022 - 10/2013
4	EnzymesIBA 11/2022 - 05/2008
4	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 07/2013
3	Growth Hormone (Somatotropin)IBA 05/2024 - 03/2019
3	Morphine (MS Contin)FDA LinkGeneric 03/2024 - 01/2022
3	VaccinesIBA 03/2024 - 12/2003
3	Opioid Analgesics (Opioids)IBA 02/2024 - 01/2021
3	Glucose (Dextrose)FDA LinkGeneric 12/2023 - 09/2016
3	LithiumIBA 11/2023 - 02/2022
3	SulfurIBA 11/2023 - 08/2019
3	Indicators and Reagents (Reagents)IBA 10/2023 - 07/2020
3	Interleukin-10 (Interleukin 10)IBA 07/2023 - 01/2016
3	Circular RNAIBA 01/2023 - 12/2021
3	Hydroxyl RadicalIBA 11/2022 - 04/2009
3	MetalsIBA 11/2022 - 09/2019
3	Analgesics (Analgesic Drugs)IBA 07/2022 - 01/2020
3	Fentanyl (Sublimaze)FDA LinkGeneric 01/2022 - 01/2020
3	Competitive Endogenous RNAIBA 12/2021 - 01/2021
3	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 10/2021 - 10/2020
3	AntigensIBA 01/2019 - 01/2016

Therapy/Procedure

36	Therapeutics 05/2024 - 07/2004
12	Immunotherapy 05/2024 - 09/2013
7	Drug Therapy (Chemotherapy) 11/2022 - 09/2014
6	Anesthesia 01/2023 - 01/2020
5	Analgesia 03/2024 - 01/2021
5	Radiotherapy 02/2024 - 01/2011
4	Deep Brain Stimulation 01/2023 - 09/2021
3	Electroacupuncture 01/2023 - 01/2022
3	General Anesthesia 01/2023 - 01/2021
3	Pediatric Anesthesia 01/2023 - 01/2022
3	Lasers (Laser) 01/2023 - 01/2014
3	Decompression 04/2021 - 07/2020
3	Thrombectomy 01/2021 - 09/2017