Linghe Zang Selected Research

Silybin (Lagosa)

9/2016	Silibinin negatively contributes to primary cilia length via autophagy regulated by histone deacetylase 6 in confluent mouse embryo fibroblast 3T3-L1 cells.
2/2016	ERβ up-regulation was involved in silibinin-induced growth inhibition of human breast cancer MCF-7 cells.
7/2015	ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells.
3/2013	Interference of silibinin with IGF-1R signalling pathways protects human epidermoid carcinoma A431 cells from UVB-induced apoptosis.

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Linghe Zang Research Topics

Disease

3	Neoplasms (Cancer) 01/2020 - 02/2016
3	Lymphoma (Lymphomas) 02/2013 - 02/2012
2	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 01/2021 - 01/2021
2	Breast Neoplasms (Breast Cancer) 02/2016 - 07/2015
1	Prostatic Neoplasms (Prostate Cancer) 02/2024
1	Necrosis 01/2021
1	Prostatitis 01/2021
1	Inflammation (Inflammations) 01/2021
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020
1	Ciliopathies 09/2016
1	Ataxia Telangiectasia (Louis Bar Syndrome) 09/2013
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/2013

Drug/Important Bio-Agent (IBA)

4	oridoninIBA 01/2020 - 02/2012
4	Silybin (Lagosa)IBA 09/2016 - 03/2013
2	Capsules (Microcapsules)IBA 01/2021 - 01/2021
1	Prostate-Specific Antigen (Semenogelase)IBA 02/2024
1	Biomarkers (Surrogate Marker)IBA 02/2024
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	Testosterone (Sustanon)FDA Link 01/2021
1	InflammasomesIBA 01/2021
1	Testosterone Propionate FDA Link 01/2021
1	Plant Preparations (Preparation, Plant)IBA 01/2021
1	Caspase 1 (ICE Protease)IBA 01/2021
1	CarrageenanIBA 01/2021
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2021
1	CytokinesIBA 01/2021
1	InterleukinsIBA 01/2021
1	HAO472IBA 01/2020
1	Cytochromes c (Cytochrome c)IBA 02/2018
1	DiterpenesIBA 02/2018
1	enmeinIBA 02/2018
1	Caspase 3 (Caspase-3)IBA 02/2018
1	Estrogen Receptor alphaIBA 07/2015
1	FlavonoidsIBA 07/2015
1	Ataxia Telangiectasia Mutated ProteinsIBA 09/2013
1	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2013
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2012

Therapy/Procedure

1	Therapeutics 02/2018