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Donald J Zack Selected Research

Neuroinflammatory Diseases

11/2021Complement component 3 from astrocytes mediates retinal ganglion cell loss during neuroinflammation.
12/2007Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanisms.

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Donald J Zack Research Topics

Disease

21Glaucoma
09/2023 - 04/2002
14Macular Degeneration (Age-Related Maculopathy)
10/2018 - 04/2002
12Retinal Degeneration
01/2018 - 04/2002
7Optic Nerve Diseases (Optic Neuropathy)
12/2023 - 10/2016
7Open-Angle Glaucoma (Glaucoma, Open Angle)
01/2018 - 01/2013
6Optic Nerve Injuries
10/2023 - 12/2007
5Retinal Diseases
01/2021 - 09/2003
5Ganglion Cysts (Ganglion)
01/2017 - 10/2008
4Retinitis Pigmentosa (Pigmentary Retinopathy)
01/2022 - 01/2010
4Vitelliform Macular Dystrophy
01/2009 - 02/2003
4Choroidal Neovascularization
10/2008 - 06/2002
3Neurodegenerative Diseases (Neurodegenerative Disease)
04/2023 - 05/2006
3Blindness (Hysterical Blindness)
10/2017 - 05/2013
2Neoplasms (Cancer)
12/2023 - 01/2021
2Wounds and Injuries (Trauma)
09/2023 - 05/2023
2Inflammation (Inflammations)
12/2022 - 11/2009
2Chronic Disease (Chronic Diseases)
01/2022 - 05/2021
2Neuroinflammatory Diseases
11/2021 - 12/2007
2Retinal Dystrophies
01/2020 - 01/2014
2Hypoxia (Hypoxemia)
09/2015 - 06/2005
2Hypersensitivity (Allergy)
02/2015 - 05/2004
2Rupture
10/2008 - 06/2002
2Ischemia
06/2005 - 03/2002
1Demyelinating Diseases (Demyelinating Disease)
03/2023
1Infections
01/2023
1Fibrosis (Cirrhosis)
01/2023
1COVID-19
09/2022
1Confusion (Bewilderment)
01/2022
1Hyperplasia
10/2021
1Lymphoma (Lymphomas)
10/2021

Drug/Important Bio-Agent (IBA)

28Retinaldehyde (Retinal)IBA
01/2023 - 02/2002
8Proteins (Proteins, Gene)FDA Link
10/2021 - 02/2002
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2010 - 02/2002
4Phosphotransferases (Kinase)IBA
01/2022 - 06/2017
4Messenger RNA (mRNA)IBA
01/2012 - 02/2002
3Sunitinib (Sutent)FDA Link
10/2023 - 05/2021
3Complement System Proteins (Complement)IBA
05/2021 - 10/2003
3Neuroprotective AgentsIBA
01/2021 - 05/2009
3MicroRNAs (MicroRNA)IBA
01/2016 - 01/2012
3Retinal Pigments (Pigments, Visual)IBA
09/2015 - 10/2008
3Brain-Derived Neurotrophic Factor (BDNF)IBA
05/2009 - 05/2003
2RNA (Ribonucleic Acid)IBA
09/2023 - 05/2023
2AntigensIBA
01/2023 - 10/2021
2Protein Isoforms (Isoforms)IBA
01/2022 - 01/2007
2Protein Kinase InhibitorsIBA
01/2022 - 03/2013
2Green Fluorescent ProteinsIBA
10/2021 - 10/2003
2Caspase 3 (Caspase-3)IBA
10/2021 - 04/2002
2Therapeutic UsesIBA
05/2021 - 01/2017
2chemotactic factor inactivatorIBA
01/2017 - 07/2013
2Deoxyribonuclease I (Nickase)IBA
02/2015 - 05/2004
2Phenylalanine (L-Phenylalanine)FDA Link
10/2014 - 10/2008
2Rhodopsin (Visual Purple)IBA
01/2013 - 01/2012
2BestrophinsIBA
01/2009 - 01/2007
2Chloride Channels (Chloride Channel)IBA
01/2007 - 02/2003
2IronIBA
05/2006 - 05/2004
2Ceruloplasmin (Ferroxidase)IBA
05/2006 - 05/2004
2Transferrin (beta 2 Transferrin)IBA
05/2006 - 05/2004
2pigment epithelium-derived factorIBA
06/2002 - 03/2002
1Lipid NanoparticlesIBA
12/2023
1Peptides (Polypeptides)IBA
10/2023
1CytokinesIBA
01/2023
1Interleukin-17 (Interleukin 17)IBA
01/2023
1InterleukinsIBA
01/2023
1CXCR4 Receptors (CXCR4 Receptor)IBA
12/2022
1plerixaforFDA Link
12/2022
11-dodecylpyridoxal (PLD)IBA
01/2022
1Indicators and Reagents (Reagents)IBA
01/2022
1Ophthalmic Solutions (Eye Drops)IBA
01/2022
1Complement C3 (C3 Complement)IBA
11/2021
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
10/2021
1Myelin Basic ProteinIBA
10/2021
1GTP Phosphohydrolases (GTPases)IBA
10/2021
1Oligodendrocyte Transcription Factor 2IBA
10/2021
1Electron Transport Complex IV (Cytochrome c Oxidase)IBA
10/2021
1poly-d-lysineIBA
10/2021
1Beclin-1IBA
10/2021
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
10/2021
1DAPIIBA
10/2021
1Matrix Metalloproteinases (MMPs)IBA
10/2021
1Dynamin IIBA
10/2021
1enhanced green fluorescent proteinIBA
10/2021
1Superoxides (Superoxide)IBA
10/2021
1bafilomycin A1IBA
10/2021
1Surface Antigens (Surface Antigen)IBA
10/2021
1MitoSox RedIBA
10/2021
1Monoclonal AntibodiesIBA
10/2021
1PTEN-induced putative kinaseIBA
10/2021
1superoxide dismutase 2IBA
10/2021
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
10/2021
1chondroitin sulfate proteoglycan 4IBA
10/2021
1tetramethylrhodamine methyl esterIBA
10/2021

Therapy/Procedure

12Therapeutics
03/2023 - 10/2003
4Lasers (Laser)
04/2016 - 10/2003
3Nerve Crush
09/2023 - 06/2012
2Immunotherapy
12/2023 - 01/2023
2Stem Cell Transplantation
12/2023 - 01/2023
2Transplantation
11/2023 - 04/2023
2Microspheres (Microsphere)
09/2023 - 05/2023
2Injections
07/2010 - 05/2003
1Length of Stay
09/2022