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Megan M Young Selected Research

Sphingolipids

1/2018Sphingolipids as Regulators of Autophagy and Endocytic Trafficking.
1/2018TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition.
7/2013Altered sphingolipid metabolism in patients with metastatic pancreatic cancer.
1/2013Sphingolipids: regulators of crosstalk between apoptosis and autophagy.

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Megan M Young Research Topics

Disease

7Neoplasms (Cancer)
01/2022 - 01/2013
2Neuroblastoma
01/2022 - 12/2010
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 11/2019
2Starvation
12/2017 - 04/2016
2Chromosomal Instability (Chromosome Stability)
07/2013 - 02/2013
2Diabetic Retinopathy (Retinopathy, Diabetic)
10/2012 - 03/2011
1Necrosis
10/2020
1Multiple Sclerosis
11/2019
1Infections
01/2017
1Human Influenza (Influenza)
01/2017
1Pancreatitis
07/2013
1Neoplasm Metastasis (Metastasis)
07/2013
1Lymphatic Metastasis
07/2013
1Pancreatic Neoplasms (Pancreatic Cancer)
07/2013
1Carcinogenesis
07/2013
1Lymphoma (Lymphomas)
02/2013
1Hyperglycemia
10/2012
1Insulin Resistance
03/2011
1Glioblastoma (Glioblastoma Multiforme)
12/2010

Drug/Important Bio-Agent (IBA)

4SphingolipidsIBA
01/2018 - 01/2013
2SphingosineIBA
11/2019 - 01/2018
2EnzymesIBA
01/2018 - 01/2018
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2017 - 07/2013
2Proteins (Proteins, Gene)FDA Link
04/2016 - 02/2013
1dinutuximabIBA
01/2022
1RNA (Ribonucleic Acid)IBA
01/2022
1Monoclonal AntibodiesIBA
01/2022
1tipifarnib (R115777)IBA
01/2022
1Farnesyltranstransferase (Farnesyltransferase)IBA
01/2022
1IronIBA
10/2020
1Lipid PeroxidesIBA
10/2020
1Peroxidase (Myeloperoxidase)IBA
10/2020
1Coenzyme A Ligases (Acid-Thiol Ligases)IBA
10/2020
1Phospholipid Hydroperoxide Glutathione PeroxidaseIBA
10/2020
1GlucocorticoidsIBA
01/2020
1Sphingosine-1-Phosphate ReceptorsIBA
11/2019
1PhosphatidylserinesIBA
11/2019
1Fingolimod Hydrochloride (FTY720)FDA Link
11/2019
1sphingosine kinaseIBA
01/2018
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2018
1IsoenzymesIBA
01/2018
1Caspase 8 (Caspase-8)IBA
12/2017
1Viral RNAIBA
01/2017
1Chemokine CXCL10IBA
07/2013
1Interleukin-6 (Interleukin 6)IBA
07/2013
1LipidsIBA
07/2013
1Epidermal Growth Factor (EGF)IBA
07/2013
1Interleukin-8 (Interleukin 8)IBA
07/2013
1CytokinesIBA
07/2013
1CeramidesIBA
07/2013
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
07/2013
1Apoptosis Regulatory ProteinsIBA
07/2013
1Caspase 3 (Caspase-3)IBA
02/2013
1Streptozocin (Streptozotocin)FDA Link
10/2012
1Retinaldehyde (Retinal)IBA
10/2012
1Insulin ReceptorIBA
10/2012
1CholesterolIBA
03/2011
1Insulin (Novolin)FDA Link
03/2011
1Glucosylceramides (Glucocerebrosides)IBA
12/2010

Therapy/Procedure

1Immunotherapy
01/2022
1Therapeutics
01/2018