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Tingxu Yan Selected Research

Caspase 3 (Caspase-3)

3/2023A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway.
12/2022Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
11/2020Salidroside from Rhodiola wallichiana var. cholaensis reverses insulin resistance and stimulates the GLP-1 secretion by alleviating ROS-mediated activation of MAPKs signaling pathway and mitigating apoptosis.

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Tingxu Yan Research Topics

Disease

12Alzheimer Disease (Alzheimer's Disease)
12/2022 - 12/2016
12Cognitive Dysfunction
03/2022 - 12/2016
10Neuroinflammatory Diseases
01/2024 - 09/2018
8Inflammation (Inflammations)
01/2024 - 09/2019
4Sleep Initiation and Maintenance Disorders (Insomnia)
01/2024 - 06/2020
3Dementia (Dementias)
06/2020 - 01/2019
2Neoplasms (Cancer)
10/2023 - 03/2023
2Dyspepsia (Indigestion)
05/2023 - 07/2022
2Body Weight (Weight, Body)
01/2023 - 05/2019
2Parkinson Disease (Parkinson's Disease)
05/2021 - 12/2019
2Hyperammonemia
04/2021 - 04/2021
2Type 2 Diabetes Mellitus (MODY)
11/2019 - 05/2019
2Memory Disorders (Memory Loss)
01/2019 - 05/2018
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2024
1Stomach Neoplasms (Stomach Cancer)
10/2023
1Colorectal Neoplasms (Colorectal Cancer)
03/2023
1Infarction (Infarctions)
12/2022
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
12/2022
1Brain Ischemia (Cerebral Ischemia)
12/2022
1Hypoxia (Hypoxemia)
09/2022
1Myocardial Ischemia (Ischemic Heart Diseases)
09/2022
1Ischemia
09/2022
1Hypoglycemia (Reactive Hypoglycemia)
05/2022
1Depressive Disorder (Melancholia)
01/2021
1Dysbiosis
12/2020
1Insulin Resistance
11/2020
1Neuroblastoma
11/2020
1Obesity
01/2020
1Sleep Deprivation
12/2019

Drug/Important Bio-Agent (IBA)

6Polysaccharides (Glycans)IBA
06/2020 - 05/2019
6Neuroprotective AgentsIBA
06/2020 - 01/2018
5LipopolysaccharidesIBA
01/2024 - 05/2018
5Brain-Derived Neurotrophic Factor (BDNF)IBA
02/2023 - 04/2019
5nootkatoneIBA
04/2021 - 01/2018
4suanzaorenIBA
01/2024 - 06/2020
4Antidepressive Agents (Antidepressants)IBA
01/2024 - 12/2019
4Proteins (Proteins, Gene)FDA Link
03/2023 - 03/2020
3Caspase 3 (Caspase-3)IBA
03/2023 - 11/2020
3rhodiolosideIBA
12/2022 - 11/2020
3LignansIBA
11/2022 - 01/2016
3schizandrinIBA
04/2021 - 12/2019
2Cisplatin (Platino)FDA LinkGeneric
05/2023 - 07/2022
2Volatile Oils (Essential Oils)IBA
01/2023 - 09/2019
2CatalaseIBA
12/2022 - 04/2021
2Superoxide DismutaseIBA
12/2022 - 04/2021
2Malondialdehyde (Propanedial)IBA
12/2022 - 04/2021
2Glucagon-Like Peptide 1 (GLP 1)IBA
07/2022 - 11/2020
2AntioxidantsIBA
04/2021 - 05/2019
2FlavonoidsIBA
01/2021 - 01/2019
2Biomarkers (Surrogate Marker)IBA
11/2020 - 06/2020
2spinosinIBA
05/2020 - 01/2019
2Amyloid (Amyloid Fibrils)IBA
05/2020 - 01/2018
2Interleukin-6 (Interleukin 6)IBA
03/2020 - 09/2019
2schisantherin BIBA
03/2019 - 12/2016
1dehydrocostus lactoneIBA
10/2023
1Mitogen-Activated Protein KinasesIBA
10/2023
1LactonesIBA
10/2023
1SesquiterpenesIBA
10/2023
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
10/2023
1Ethanol (Ethyl Alcohol)IBA
03/2023
1Therapeutic UsesIBA
03/2023
1Eosine Yellowish-(YS) (Eosin)IBA
03/2023
1Hematoxylin (Haematoxylon)IBA
03/2023
1chrysinIBA
02/2023
1ethyl 6- (N- (2- chloro- 4- fluorophenyl)sulfamoyl)cyclohex- 1- ene- 1- carboxylateIBA
01/2023
1Sucrose (Saccharose)IBA
01/2023
1AluminumIBA
12/2022
1IonsIBA
12/2022
1ThioredoxinsIBA
12/2022
1Glucose (Dextrose)FDA LinkGeneric
12/2022
1MetalsIBA
12/2022
1Oxygen (Dioxygen)IBA
12/2022
1AntralIBA
07/2022
1milk-thistle extractIBA
05/2022
1Estrogen ReceptorsIBA
05/2022
1Silybin (Lagosa)IBA
05/2022
1SilymarinIBA
05/2022
1Glutathione (Reduced Glutathione)IBA
04/2021
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
04/2021
1CytokinesIBA
04/2021
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
04/2021
1GalactosamineIBA
04/2021
1Alanine Transaminase (SGPT)IBA
04/2021
1Volatile Fatty AcidsIBA
12/2020
116S Ribosomal RNAIBA
12/2020
1p38 Mitogen-Activated Protein KinasesIBA
11/2020
1PalmitatesIBA
11/2020
1Glucosamine (Dona)IBA
11/2020
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
11/2020
1Lipoprotein Receptors (Lipoprotein Receptor)IBA
06/2020
1Phenylalanine (L-Phenylalanine)FDA Link
06/2020
1Tryptophan (L-Tryptophan)FDA Link
06/2020
1Insulin (Novolin)FDA Link
01/2020
1schisandrol AIBA
12/2019
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2019
1Triglycerides (Triacylglycerol)IBA
05/2019

Therapy/Procedure

2Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2024 - 06/2020
2Intraperitoneal Injections
12/2022 - 05/2019
1Ovariectomy (Oophorectomy)
01/2024
1Subcutaneous Injections
03/2023