Jian Xu Selected Research

Pancreatic Neoplasms (Pancreatic Cancer)

1/2024	A novel method for detection of pancreatic Ductal Adenocarcinoma using explainable machine learning.
1/2024	Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance.
1/2023	USP33 promotes pancreatic cancer malignant phenotype through the regulation of TGFBR2/TGFβ signaling pathway.
1/2023	Galectin-9 and PD-L1 antibody blockade combination therapy inhibits tumour progression in pancreatic cancer.
1/2023	Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer.
11/2022	Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis.
6/2022	The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer.
1/2022	LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.
1/2022	Combination cancer immunotherapy targeting TNFR2 and PD-1/PD-L1 signaling reduces immunosuppressive effects in the microenvironment of pancreatic tumors.
12/2021	Detection of pancreatic cancer by indocyanine green-assisted fluorescence imaging in the first and second near-infrared windows.

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Jian Xu Research Topics

Disease

240	Neoplasms (Cancer) 04/2024 - 09/2002
70	Infections 04/2024 - 07/2003
48	Inflammation (Inflammations) 04/2024 - 06/2008
42	Neoplasm Metastasis (Metastasis) 04/2024 - 10/2008
29	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 09/2002
28	Pancreatic Neoplasms (Pancreatic Cancer) 01/2024 - 04/2014
23	Colorectal Neoplasms (Colorectal Cancer) 02/2024 - 07/2014
23	Fibrosis (Cirrhosis) 12/2023 - 02/2002
23	Carcinogenesis 12/2023 - 01/2002
19	Lung Neoplasms (Lung Cancer) 04/2024 - 08/2009
18	Breast Neoplasms (Breast Cancer) 04/2024 - 01/2016
18	Body Weight (Weight, Body) 04/2024 - 01/2004
17	Colonic Neoplasms (Colon Cancer) 02/2024 - 03/2005
17	Pain (Aches) 10/2023 - 06/2010
15	Stomach Neoplasms (Stomach Cancer) 11/2023 - 06/2006
15	Hemorrhage 01/2023 - 09/2003
15	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 01/2012
14	Ischemia 04/2024 - 02/2006
14	Myocardial Infarction 12/2023 - 01/2004
14	Hypertension (High Blood Pressure) 01/2023 - 11/2003
13	Wounds and Injuries (Trauma) 03/2024 - 09/2011
13	Stroke (Strokes) 01/2024 - 05/2008
13	Tuberculosis (Tuberculoses) 01/2024 - 11/2011
13	COVID-19 10/2023 - 01/2020
13	Carcinoma (Carcinomatosis) 01/2023 - 04/2011
13	Alzheimer Disease (Alzheimer's Disease) 11/2021 - 04/2004
12	Cognitive Dysfunction 03/2024 - 01/2016
12	Rheumatoid Arthritis 06/2023 - 06/2008
12	Infarction (Infarctions) 03/2023 - 02/2006
12	Insulin Resistance 01/2023 - 06/2009
12	Heart Failure 10/2022 - 01/2004
12	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 03/2007
12	Hypoxia (Hypoxemia) 01/2022 - 11/2009
11	Atherosclerosis 03/2024 - 01/2005
11	Adenocarcinoma 01/2024 - 06/2006
11	Adenocarcinoma of Lung 01/2023 - 01/2012
11	Type 2 Diabetes Mellitus (MODY) 01/2023 - 01/2013
11	Hypertrophy 01/2022 - 01/2004
10	Atrial Fibrillation 02/2024 - 02/2011
10	Necrosis 12/2023 - 09/2014
10	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2023 - 09/2010
10	Glioma (Gliomas) 11/2022 - 06/2004
9	Diabetes Mellitus 04/2024 - 02/2006
9	Asthma (Bronchial Asthma) 01/2024 - 05/2009
9	Liver Neoplasms (Liver Cancer) 01/2024 - 01/2012
9	Thyroid Diseases (Thyroid Disease) 01/2022 - 01/2006
9	Obesity 01/2021 - 02/2013
8	Traumatic Brain Injuries (Traumatic Brain Injury) 03/2024 - 06/2011
8	Virus Diseases (Viral Diseases) 01/2024 - 05/2006
8	Pulmonary Arterial Hypertension 09/2023 - 12/2016
8	Lymphatic Metastasis 03/2023 - 10/2011
8	Leukemia 01/2023 - 04/2006
8	Cardiomegaly (Heart Hypertrophy) 01/2021 - 01/2004
8	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 02/2014

Drug/Important Bio-Agent (IBA)

114	Proteins (Proteins, Gene)FDA Link 04/2024 - 12/2002
47	Biomarkers (Surrogate Marker)IBA 04/2024 - 02/2011
36	Messenger RNA (mRNA)IBA 01/2024 - 03/2005
31	MicroRNAs (MicroRNA)IBA 02/2023 - 02/2011
27	Therapeutic UsesIBA 02/2024 - 04/2002
23	Long Noncoding RNAIBA 11/2022 - 01/2017
19	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 06/2005
19	Interleukin-6 (Interleukin 6)IBA 01/2024 - 01/2013
18	CytokinesIBA 01/2024 - 10/2004
17	Small Interfering RNA (siRNA)IBA 11/2021 - 05/2010
16	RNA (Ribonucleic Acid)IBA 01/2024 - 09/2002
16	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 12/2005
15	CollagenIBA 12/2023 - 05/2005
15	Insulin (Novolin)FDA Link 01/2023 - 12/2003
14	Phosphotransferases (Kinase)IBA 02/2023 - 07/2013
13	EnzymesIBA 01/2024 - 09/2003
13	Indicators and Reagents (Reagents)IBA 07/2022 - 01/2011
13	LipidsIBA 09/2021 - 09/2011
12	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2022 - 03/2008
11	LipopolysaccharidesIBA 01/2024 - 06/2013
11	Transcription Factors (Transcription Factor)IBA 01/2022 - 09/2002
10	Caspase 3 (Caspase-3)IBA 04/2024 - 01/2013
10	Anti-Bacterial Agents (Antibiotics)IBA 04/2024 - 08/2010
10	Circular RNAIBA 02/2024 - 01/2018
10	AntigensIBA 11/2023 - 06/2008
10	VaccinesIBA 12/2022 - 12/2009
10	Protein Tyrosine PhosphatasesIBA 01/2020 - 05/2008
9	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2019 - 10/2007
8	C-Reactive ProteinIBA 02/2024 - 10/2006
8	LigandsIBA 01/2024 - 11/2005
8	InterferonsIBA 01/2024 - 03/2017
8	Antiviral Agents (Antivirals)IBA 01/2024 - 01/2018
8	Immune Checkpoint InhibitorsIBA 01/2024 - 01/2018
8	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2023 - 01/2016
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 10/2003
8	Blood Glucose (Blood Sugar)IBA 03/2022 - 09/2007
8	Tyrosine (L-Tyrosine)FDA Link 01/2019 - 09/2009

Therapy/Procedure

114	Therapeutics 03/2024 - 09/2003
38	Drug Therapy (Chemotherapy) 02/2024 - 03/2009
19	Immunotherapy 01/2024 - 12/2009
18	Transplantation 10/2022 - 12/2003
14	Radiotherapy 01/2023 - 01/2012
13	Aftercare (After-Treatment) 07/2023 - 01/2007
11	Kidney Transplantation 11/2023 - 04/2002
9	Chinese Traditional Medicine (Traditional Chinese Medicine) 11/2023 - 04/2013
7	Liver Transplantation 04/2024 - 05/2006