Cen Xie Selected Research

6-ethyl-24-norcholane-3,7,23-triol-23 sulfate

11/2022	The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice.
1/2018	FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Cen Xie Research Topics

Disease

16	Obesity 01/2024 - 12/2015
10	Non-alcoholic Fatty Liver Disease 12/2023 - 01/2015
10	Neoplasms (Cancer) 01/2023 - 04/2013
7	Insulin Resistance 01/2024 - 09/2016
7	Inflammation (Inflammations) 10/2023 - 01/2019
6	Fibrosis (Cirrhosis) 10/2023 - 01/2018
3	Body Weight (Weight, Body) 01/2024 - 01/2016
3	Fatty Liver 01/2024 - 09/2016
3	Type 2 Diabetes Mellitus (MODY) 01/2023 - 01/2018
3	Hypoxia (Hypoxemia) 02/2021 - 01/2018
2	Hyperglycemia 10/2022 - 12/2018
2	Metabolic Diseases (Metabolic Disease) 05/2022 - 01/2017
2	Liver Diseases (Liver Disease) 05/2022 - 01/2020
2	Colitis 01/2022 - 01/2020
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 01/2018
2	Carcinogenesis 10/2021 - 01/2019
2	Hepatocellular Carcinoma (Hepatoma) 10/2021 - 12/2018
2	Colonic Neoplasms (Colon Cancer) 01/2019 - 01/2016
2	Necrosis 11/2016 - 05/2016
2	Brain Ischemia (Cerebral Ischemia) 04/2014 - 02/2013
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2024
1	Major Depressive Disorder (Major Depressive Disorders) 02/2023
1	Adenocarcinoma of Lung 01/2023
1	Pruritus (Itching) 12/2022
1	Dysbiosis 11/2022
1	Choline Deficiency 10/2022
1	Tics (Tic) 01/2022
1	Kidney Diseases (Kidney Disease) 01/2022
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022
1	Ischemia 01/2022
1	Acute Kidney Injury (Acute Renal Failure) 01/2022
1	Reperfusion Injury 01/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022

Drug/Important Bio-Agent (IBA)

13	Bile Acids and Salts (Bile Acids)IBA 01/2024 - 11/2016
7	Glucose (Dextrose)FDA LinkGeneric 01/2024 - 01/2017
5	CeramidesIBA 01/2023 - 01/2015
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 01/2017
4	LipidsIBA 01/2024 - 01/2018
4	Glycine (Aminoacetic Acid)FDA LinkGeneric 04/2023 - 12/2015
4	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 05/2022 - 01/2015
3	muricholic acidIBA 12/2022 - 12/2015
2	Triglycerides (Triacylglycerol)IBA 01/2024 - 01/2022
2	LeptinIBA 01/2024 - 04/2023
2	16S Ribosomal RNAIBA 01/2024 - 12/2022
2	CholesterolIBA 01/2024 - 11/2022
2	hyodeoxycholic acidIBA 10/2023 - 01/2023
2	RNA (Ribonucleic Acid)IBA 10/2023 - 01/2022
2	Glutamine (L-Glutamine)FDA Link 10/2023 - 04/2023
2	caffeoylquinic acidIBA 08/2023 - 12/2022
2	Methionine (L-Methionine)FDA Link 04/2023 - 10/2022
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2023 - 12/2022
2	6-ethyl-24-norcholane-3,7,23-triol-23 sulfateIBA 11/2022 - 01/2018
2	AcidsIBA 11/2022 - 10/2011
2	Glucagon-Like Peptide 1 (GLP 1)IBA 10/2022 - 10/2018
2	Insulin (Novolin)FDA Link 10/2022 - 01/2017
2	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA 10/2021 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 02/2021 - 01/2019
2	Dextran SulfateIBA 01/2020 - 01/2019
2	Messenger RNA (mRNA)IBA 01/2019 - 12/2018
2	GTP-Binding Proteins (G-Protein)IBA 10/2018 - 01/2017
2	3-n-butylphthalide (butylphthalide)IBA 04/2014 - 02/2013
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2024
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2024
1	Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA 11/2023
1	Isoleucine (L-Isoleucine)FDA Link 04/2023
1	Amino Acids FDA Link 04/2023
1	Tyrosine (L-Tyrosine)FDA Link 04/2023
1	3-nitrophenylhydrazineIBA 04/2023
1	Ribosomal DNA (rDNA)IBA 04/2023
1	Leucine (L-Leucine)FDA Link 04/2023
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 02/2023
1	Deoxyglucose (2 Deoxy D glucose)IBA 01/2023
1	caffeic acid phenethyl esterIBA 01/2023
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2023
1	N-palmitoylsphingosineIBA 01/2023
1	choloylglycine hydrolaseIBA 01/2023
1	Propolis (Bee Bread)IBA 01/2023
1	Blood Glucose (Blood Sugar)IBA 01/2023
1	Therapeutic UsesIBA 01/2023
1	Xanthine DehydrogenaseIBA 01/2023
1	PropionatesIBA 12/2022
1	LDL Lipoproteins (beta Lipoproteins)IBA 12/2022
1	Betulinic AcidIBA 10/2022
1	Islet Amyloid PolypeptideIBA 10/2022
1	Polysaccharides (Glycans)IBA 08/2022
1	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 05/2022
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 05/2022
1	EnzymesIBA 05/2022
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 05/2022
1	XenobioticsIBA 05/2022
1	PPAR alphaIBA 05/2022
1	Cholestyramine Resin (Questran)FDA LinkGeneric 01/2022
1	Cholic AcidIBA 01/2022
1	AMP-Activated Protein KinasesIBA 01/2022
1	Nonesterified Fatty Acids (NEFA)IBA 01/2022

Therapy/Procedure

3	Therapeutics 12/2023 - 01/2017
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 12/2023 - 05/2016
2	Intraperitoneal Injections 01/2017 - 01/2016
1	Transplantation 10/2023
1	Fecal Microbiota Transplantation 12/2022