Cheng-Wen Wu Selected Research

Lung Neoplasms (Lung Cancer)

9/2020	Low-Dose Nicotine Activates EGFR Signaling via α5-nAChR and Promotes Lung Adenocarcinoma Progression.
10/2018	Enhanced YAP expression leads to EGFR TKI resistance in lung adenocarcinomas.
1/2018	EGFR-mediated interleukin enhancer-binding factor 3 contributes to formation and survival of cancer stem-like tumorspheres as a therapeutic target against EGFR-positive non-small cell lung cancer.
1/2017	YM155 as an inhibitor of cancer stemness simultaneously inhibits autophosphorylation of epidermal growth factor receptor and G9a-mediated stemness in lung cancer cells.
12/2016	Epigenetic Switch between SOX2 and SOX9 Regulates Cancer Cell Plasticity.
2/2016	Galectin-3 modulates the EGFR signalling-mediated regulation of Sox2 expression via c-Myc in lung cancer.
1/2016	MicroRNA-7 Compromises p53 Protein-dependent Apoptosis by Controlling the Expression of the Chromatin Remodeling Factor SMARCD1.
1/2014	PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activation of MMP2.
8/2013	The PML isoform IV is a negative regulator of nuclear EGFR's transcriptional activity in lung cancer.
11/2010	EGFR promotes lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF.

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Cheng-Wen Wu Research Topics

Disease

47	Neoplasms (Cancer) 01/2022 - 07/2002
13	Lung Neoplasms (Lung Cancer) 09/2020 - 07/2003
11	Neoplasm Metastasis (Metastasis) 12/2019 - 01/2003
10	Adenocarcinoma of Lung 01/2022 - 09/2010
9	Carcinogenesis 01/2019 - 01/2005
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 12/2006
3	Breast Neoplasms (Breast Cancer) 01/2012 - 07/2002
3	Melanoma (Melanoma, Malignant) 07/2003 - 01/2003
2	Hypoxia (Hypoxemia) 01/2019 - 09/2017
2	Acute Lung Injury 11/2013 - 01/2013
2	Fibrosarcoma 01/2010 - 05/2006
2	Brain Diseases (Brain Disorder) 09/2009 - 01/2007
2	Mucoepidermoid Carcinoma 09/2005 - 05/2003
2	Carcinoma (Carcinomatosis) 08/2005 - 07/2003
2	Colonic Neoplasms (Colon Cancer) 07/2003 - 01/2003
1	Vascular Calcification 01/2021
1	Atrophy 01/2019
1	Endometrial Neoplasms (Endometrial Cancer) 01/2018
1	Lymphatic Metastasis 01/2018
1	Neurodegenerative Diseases (Neurodegenerative Disease) 08/2017
1	Oncogene Addiction 04/2016
1	Vascular Tissue Neoplasms 03/2016
1	Adenocarcinoma 03/2014
1	Ventilator-Induced Lung Injury 01/2013
1	Brain Neoplasms (Brain Tumor) 09/2009
1	Central Nervous System Cavernous Hemangioma 09/2009
1	Squamous Cell Carcinoma of Head and Neck 01/2009
1	Ovarian Neoplasms (Ovarian Cancer) 12/2006
1	Retinitis 11/2006

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 12/2019 - 04/2002
8	ErbB Receptors (EGF Receptor)IBA 10/2018 - 11/2010
6	DNA (Deoxyribonucleic Acid)IBA 08/2017 - 01/2003
3	Tyrosine Kinase InhibitorsIBA 01/2021 - 10/2017
3	Transcription Factors (Transcription Factor)IBA 01/2019 - 09/2010
3	Peptides (Polypeptides)IBA 01/2019 - 01/2010
3	Messenger RNA (mRNA)IBA 01/2018 - 02/2003
3	Epithelial Cell Adhesion MoleculeIBA 01/2018 - 01/2009
3	MicroRNAs (MicroRNA)IBA 01/2016 - 11/2010
3	Cadherins (E-Cadherin)IBA 06/2011 - 05/2003
3	Small Interfering RNA (siRNA)IBA 08/2010 - 12/2005
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2022 - 01/2018
2	Aurora Kinase AIBA 01/2022 - 01/2021
2	Phosphotransferases (Kinase)IBA 01/2021 - 04/2016
2	Protein Isoforms (Isoforms)IBA 01/2019 - 08/2013
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 11/2010
2	sepantroniumIBA 01/2018 - 01/2017
2	CateninsIBA 09/2017 - 05/2003
2	Oncostatin MIBA 09/2016 - 11/2012
2	RNA (Ribonucleic Acid)IBA 01/2015 - 02/2003
2	Promyelocytic Leukemia ProteinIBA 01/2014 - 08/2013
2	Kallikreins (Kallikrein)IBA 06/2011 - 12/2006
2	Therapeutic UsesIBA 04/2011 - 01/2003
2	beta CateninIBA 07/2009 - 05/2003
2	AntigensIBA 08/2005 - 07/2003
2	Interleukin-12 (IL 12)IBA 07/2003 - 01/2003
2	Monoclonal AntibodiesIBA 07/2003 - 01/2003
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2022
1	ThymidineIBA 01/2022
1	Growth Factor ReceptorsIBA 01/2021
1	Advanced Glycation End ProductsIBA 01/2021
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 09/2020
1	Nicotine FDA Link 09/2020
1	SmokeIBA 09/2020
1	Thiostrepton (Gargon)IBA 12/2019
1	src-Family KinasesIBA 12/2019
1	Oxygen (Dioxygen)IBA 01/2019
1	pigment epithelium-derived factorIBA 01/2019
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2018
1	Nuclear Factor 90 ProteinsIBA 01/2018
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 08/2017
1	A-Form DNA (A-DNA)IBA 08/2017
1	soyasaponin IIBA 04/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2016
1	AngiopoietinsIBA 03/2016
1	Galectin 3 (LGALS3)IBA 02/2016
1	InterferonsIBA 01/2014
1	PolyethyleneimineIBA 11/2013
1	Conditioned Culture MediaIBA 01/2013
1	Laminin (Merosin)IBA 06/2011
1	SurvivinIBA 04/2011
1	Oncogene Proteins (Oncogene Protein)IBA 08/2010
1	N-acetyltryptophanamide (NATA)IBA 08/2010
1	N-Terminal AcetyltransferasesIBA 08/2010
1	PPAR gammaIBA 03/2010
1	Rosiglitazone (Avandia)FDA Link 03/2010
1	PlacebosIBA 03/2010
1	triptolideIBA 03/2010
1	Mitogen-Activated Protein KinasesIBA 03/2010
1	Amino Acids FDA Link 01/2010
1	Protease Inhibitors (Protease Inhibitor)IBA 09/2009
1	Transcription Factor 7-Like 2 ProteinIBA 07/2009
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 01/2007
1	Peptide Hydrolases (Proteases)FDA Link 12/2006
1	IntegrinsIBA 12/2006
1	Fibronectins (Fibronectin)IBA 12/2006
1	CASP8 and FADD-Like Apoptosis Regulating Protein (FLIP-S)IBA 11/2006

Therapy/Procedure

7	Therapeutics 10/2018 - 07/2003
2	Drug Therapy (Chemotherapy) 12/2019 - 01/2016
2	Intravenous Injections 01/2010 - 05/2006
1	Artificial Respiration (Mechanical Ventilation) 01/2013