Olaf Witt Selected Research

MicroRNAs (MicroRNA)

6/2014	Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing.
7/2013	MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
4/2012	MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma.

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Olaf Witt Research Topics

Disease

87	Neoplasms (Cancer) 05/2024 - 09/2006
30	Neuroblastoma 01/2023 - 04/2008
22	Medulloblastoma 01/2024 - 02/2009
20	Glioma (Gliomas) 04/2024 - 11/2013
12	Astrocytoma (Pilocytic Astrocytoma) 01/2023 - 04/2011
9	Brain Neoplasms (Brain Tumor) 01/2023 - 07/2013
8	Ependymoma 11/2021 - 01/2009
5	Glioblastoma (Glioblastoma Multiforme) 01/2023 - 08/2004
5	Carcinogenesis 01/2022 - 01/2009
5	Tuberous Sclerosis (Bourneville's Disease) 01/2019 - 01/2013
3	Disease Progression 01/2023 - 03/2009
3	Stomatitis 01/2023 - 01/2013
3	Carcinoma (Carcinomatosis) 01/2023 - 07/2008
3	Rhabdomyosarcoma 10/2012 - 02/2009
2	Anemia 11/2023 - 01/2019
2	Typical Teratoid Rhabdoid Tumor 01/2023 - 01/2019
2	Genomic Instability 11/2021 - 12/2019
2	Neurologic Manifestations (Neurological Manifestations) 01/2020 - 01/2019
2	Leukemia 12/2019 - 09/2006
2	Sarcoma (Soft Tissue Sarcoma) 04/2018 - 09/2010
2	Myeloid Leukemia (Leukemia, Myelocytic) 01/2016 - 09/2006
2	Intellectual Disability (Idiocy) 07/2015 - 01/2012
2	Neoplasm Metastasis (Metastasis) 04/2012 - 03/2009
2	Retinoblastoma (Glioblastoma, Retinal) 06/2008 - 04/2008
1	Central Nervous System Neoplasms 11/2023
1	Drug-Related Side Effects and Adverse Reactions 01/2023
1	Inflammation (Inflammations) 01/2023

Drug/Important Bio-Agent (IBA)

27	Histone Deacetylase InhibitorsIBA 01/2024 - 03/2003
18	Histone Deacetylases (Histone Deacetylase)IBA 01/2023 - 03/2003
10	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2008
9	Mitogen-Activated Protein KinasesIBA 01/2024 - 01/2009
9	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 02/2009
7	Vorinostat FDA Link 01/2021 - 09/2010
6	RNA (Ribonucleic Acid)IBA 11/2023 - 08/2012
6	ChromatinIBA 01/2023 - 01/2012
6	Transcription Factors (Transcription Factor)IBA 01/2022 - 11/2008
5	Biomarkers (Surrogate Marker)IBA 09/2021 - 05/2015
5	Messenger RNA (mRNA)IBA 11/2019 - 01/2009
5	Everolimus FDA Link 01/2019 - 01/2013
4	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2020 - 07/2013
4	Valproic Acid (Depakote)FDA LinkGeneric 08/2010 - 08/2004
3	tovorafenibIBA 03/2024 - 11/2023
3	trametinibIBA 11/2023 - 09/2020
3	Vincristine (Oncovin)FDA LinkGeneric 09/2023 - 11/2017
3	entinostat (MS 275)IBA 05/2023 - 06/2020
3	Histones (Histone)IBA 01/2023 - 07/2008
3	trans-sodium crocetinate (crocetin)IBA 01/2019 - 01/2016
3	TOR Serine-Threonine KinasesIBA 08/2016 - 01/2013
3	IsoenzymesIBA 04/2015 - 07/2013
3	MicroRNAs (MicroRNA)IBA 06/2014 - 04/2012
2	Conditioned Culture MediaIBA 04/2024 - 01/2019
2	Drug CombinationsIBA 01/2024 - 10/2020
2	dabrafenibIBA 11/2023 - 09/2023
2	Tyrosine Kinase InhibitorsIBA 01/2023 - 10/2008
2	Phosphotransferases (Kinase)IBA 01/2023 - 01/2020
2	N 30IBA 07/2021 - 12/2020
2	ErbB Receptors (EGF Receptor)IBA 01/2021 - 10/2008
2	ProteomeIBA 01/2021 - 01/2020
2	PCI 34051IBA 01/2020 - 12/2018
2	NucleotidesIBA 12/2019 - 01/2016
2	Formaldehyde (Formol)FDA Link 11/2019 - 05/2015
2	ParaffinIBA 11/2019 - 05/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 01/2010
2	Differentiation AntigensIBA 01/2018 - 11/2008
2	Dactinomycin (Actinomycin)FDA LinkGeneric 11/2017 - 09/2016
2	ZincIBA 01/2016 - 05/2013
2	Small Interfering RNA (siRNA)IBA 06/2010 - 11/2008
2	Cisplatin (Platino)FDA LinkGeneric 10/2008 - 05/2002
2	HC toxinIBA 06/2008 - 04/2008
1	CytokinesIBA 04/2024
1	Creatine Kinase (Creatine Phosphokinase)IBA 11/2023
1	Carboplatin (JM8)FDA LinkGeneric 09/2023
1	Adenosine Triphosphate (ATP)IBA 05/2023
1	tacedinaline (CI 994)IBA 01/2023
1	Tumor Viral Antigens (Large T Antigen)IBA 01/2023
1	erdafitinibIBA 01/2023
1	SenotherapeuticsIBA 01/2023
1	Trypan Blue FDA Link 01/2023
1	AfatinibIBA 01/2023
1	tariquidar (XR9576)IBA 01/2023
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2023
1	tyrosine receptor (receptor, tyrosine)IBA 01/2023
1	ulixertinibIBA 01/2023
1	Dihydrotachysterol (AT 10)IBA 07/2022
1	sonidegibIBA 01/2022
1	Proto-Oncogene Proteins c-etsIBA 01/2022

Therapy/Procedure

52	Therapeutics 05/2024 - 04/2008
15	Drug Therapy (Chemotherapy) 01/2024 - 08/2010
4	Precision Medicine 01/2023 - 01/2016
4	Investigational Therapies (Experimental Therapy) 10/2021 - 01/2016
4	Radiotherapy 01/2021 - 08/2010
3	Aftercare (After-Treatment) 07/2021 - 01/2016
2	Chemoradiotherapy 01/2020 - 03/2009
2	Combined Modality Therapy 10/2016 - 08/2010
2	Oncolytic Virotherapy 01/2016 - 09/2010
2	Transplantation 12/2012 - 11/2011
1	Immunotherapy 01/2023
1	Heterologous Transplantation (Xenotransplantation) 01/2023
1	Duration of Therapy 12/2022
1	Operative Surgical Procedures 07/2022