Konstanze F Winklhofer Selected Research

Amyloid (Amyloid Fibrils)

8/2021	Remodeling of the Fibrillation Pathway of α-Synuclein by Interaction with Antimicrobial Peptide LL-III.
12/2012	The heat shock response is modulated by and interferes with toxic effects of scrapie prion protein and amyloid β.
1/2012	Cellular prion protein mediates toxic signaling of amyloid beta.
4/2008	Observing fibrillar assemblies on scrapie-infected cells.
6/2005	Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets.

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Konstanze F Winklhofer Research Topics

Disease

19	Prion Diseases (Transmissible Spongiform Encephalopathies) 09/2023 - 04/2003
14	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2023 - 02/2005
14	Parkinson Disease (Parkinson's Disease) 08/2021 - 06/2005
11	Scrapie 01/2018 - 05/2003
6	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 06/2005
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 02/2012
4	Parkinsonian Disorders (Parkinsonism) 06/2014 - 11/2007
3	Neuroblastoma 02/2014 - 05/2003
2	Proteostasis Deficiencies 12/2023 - 01/2019
2	Multiple Sclerosis 01/2020 - 10/2017
1	Frontotemporal Dementia (Semantic Dementia) 01/2021
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021
1	Inflammation (Inflammations) 01/2021
1	Infections 01/2021
1	Persistent Infection 01/2021
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2017
1	Tauopathies 01/2017
1	Leigh Disease (Leigh's Disease) 08/2013
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2008

Drug/Important Bio-Agent (IBA)

19	Prion ProteinsIBA 09/2023 - 04/2003
13	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2005
9	PrionsIBA 01/2021 - 06/2004
8	Protein Isoforms (Isoforms)IBA 09/2023 - 09/2004
6	SynucleinsIBA 12/2023 - 10/2010
5	Amyloid (Amyloid Fibrils)IBA 08/2021 - 06/2005
5	Phosphotransferases (Kinase)IBA 01/2021 - 11/2007
5	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2020 - 07/2010
3	Protein AggregatesIBA 09/2023 - 01/2021
2	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 05/2015 - 02/2014
2	Peptides (Polypeptides)IBA 12/2012 - 02/2005
2	polyglutamineIBA 01/2010 - 08/2006
1	UbiquitinIBA 12/2023
1	AntigensIBA 01/2021
1	Oxidants (Oxidizing Agents)IBA 01/2021
1	Blood Proteins (Serum Proteins)IBA 01/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021
1	PTEN-induced putative kinaseIBA 01/2021
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2021
1	Hypochlorous Acid (Hypochlorite)IBA 01/2021
1	propionic acid (potassium propionate)IBA 01/2020
1	LigandsIBA 01/2018
1	laquinimodIBA 10/2017
1	annonacinIBA 01/2017
1	NeurotoxinsIBA 01/2017
1	RNA (Ribonucleic Acid)IBA 01/2017
1	alpha-SynucleinIBA 01/2017
1	Leucine (L-Leucine)FDA Link 08/2013
1	Endopeptidase K (Proteinase K)IBA 04/2008
1	Detergents (Detergent)IBA 04/2008
1	parkin proteinIBA 12/2007
1	TensinsIBA 11/2007
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2007
1	PrPSc ProteinsIBA 06/2006
1	Glycoproteins (Glycoprotein)IBA 06/2005
1	Amyloidogenic ProteinsIBA 02/2005
1	Amyloid beta-PeptidesIBA 02/2005
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 02/2005
1	CopperIBA 06/2004
1	Suramin (Suramin Sodium)IBA 06/2004
1	Mannose (D-Mannose)IBA 05/2003

Therapy/Procedure

1	Therapeutics 01/2022