Martin Wepler Selected Research

Inflammation (Inflammations)

1/2022	Systemic calcitonin gene-related peptide receptor antagonism decreases survival in a porcine model of polymicrobial sepsis: blinded randomised controlled trial.
12/2020	Impact of downstream effects of glucocorticoid receptor dysfunction on organ function in critical illness-associated systemic inflammation.
1/2020	Effects of sodium thiosulfate (Na2S2O3) during resuscitation from hemorrhagic shock in swine with preexisting atherosclerosis.
1/2019	The Mitochondria-Targeted H2S-Donor AP39 in a Murine Model of Combined Hemorrhagic Shock and Blunt Chest Trauma.
1/2019	In-Depth Characterization of the Effects of Cigarette Smoke Exposure on the Acute Trauma Response and Hemorrhage in Mice.
1/2019	Effects of Psychosocial Stress on Subsequent Hemorrhagic Shock and Resuscitation in Male Mice.
1/2019	Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction.
10/2018	Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart.
1/2017	Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43.

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Martin Wepler Research Topics

Disease

10	Wounds and Injuries (Trauma) 01/2021 - 01/2015
9	Hemorrhagic Shock 01/2022 - 05/2016
9	Inflammation (Inflammations) 01/2022 - 01/2017
8	Hemorrhage 01/2020 - 10/2018
8	Atherosclerosis 01/2020 - 12/2013
7	Septic Shock (Toxic Shock Syndrome) 01/2022 - 12/2013
7	Shock 01/2022 - 12/2013
6	Sepsis (Septicemia) 01/2022 - 12/2016
4	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020 - 01/2017
4	Hyperoxia 10/2019 - 05/2016
4	Hypercholesterolemia 10/2018 - 12/2013
4	Peritonitis 10/2018 - 12/2013
3	Hypotension (Low Blood Pressure) 01/2022 - 12/2013
3	Acute Lung Injury 12/2020 - 01/2019
3	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 01/2020 - 12/2017
3	Hypoxia (Hypoxemia) 01/2019 - 05/2016
2	COVID-19 02/2022 - 04/2021
2	Acidosis 01/2022 - 10/2017
2	Lung Injury 12/2021 - 01/2017
2	Respiratory Insufficiency (Respiratory Failure) 04/2021 - 02/2014
2	Brain Injuries (Brain Injury) 01/2021 - 12/2019
2	Reperfusion Injury 01/2020 - 10/2018
2	Acute Kidney Injury (Acute Renal Failure) 10/2018 - 12/2013
2	Lactic Acidosis 10/2018 - 12/2013
2	Pulmonary Hypertension 01/2018 - 11/2016
2	B-Cell Lymphoma (Lymphoma, B Cell) 01/2017 - 05/2016
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2022
1	Infections 04/2021
1	Viral Pneumonia 04/2021
1	Acute Subdural Hematoma 01/2021
1	Critical Illness (Critically Ill) 12/2020
1	Brain Ischemia (Cerebral Ischemia) 01/2020
1	Gliosis 12/2019
1	Ischemia 01/2019
1	Traumatic Brain Injuries (Traumatic Brain Injury) 11/2018
1	Spinal Cord Ischemia 10/2018
1	Body Weight (Weight, Body) 10/2018
1	Arteriosclerosis 10/2018

Drug/Important Bio-Agent (IBA)

10	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2020 - 12/2013
8	3-nitrotyrosineIBA 12/2019 - 02/2015
7	CytokinesIBA 01/2022 - 02/2015
7	salicylhydroxamic acid (SHAM)IBA 01/2020 - 02/2015
5	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 12/2020 - 01/2017
4	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2022 - 01/2020
4	SmokeIBA 01/2022 - 01/2017
4	GlucocorticoidsIBA 12/2021 - 01/2019
4	Oxygen (Dioxygen)IBA 01/2021 - 05/2016
4	GasesIBA 01/2020 - 05/2016
4	LyasesIBA 01/2020 - 05/2016
4	CystathionineIBA 01/2020 - 05/2016
4	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 10/2019 - 05/2016
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 05/2016
3	AlbuminsIBA 12/2019 - 05/2016
3	CreatinineIBA 10/2018 - 01/2017
3	Glucose (Dextrose)FDA LinkGeneric 10/2018 - 01/2017
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018 - 11/2016
2	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2022 - 12/2020
2	CatecholaminesIBA 01/2022 - 10/2017
2	EnzymesIBA 01/2020 - 12/2017
2	Sulfides (Thioethers)IBA 01/2019 - 10/2018
2	GYY 4137IBA 10/2018 - 01/2017
2	Lactic Acid (Lactate)FDA LinkGeneric 09/2018 - 10/2017
2	AcidsIBA 01/2017 - 05/2016
2	Heme Oxygenase-1IBA 01/2017 - 05/2016
2	Purinergic Receptors (Receptors, Purine)IBA 01/2017 - 02/2015
1	Azithromycin (Zithromax)FDA LinkGeneric 02/2022
1	Cholecalciferol (Vitamin D3)FDA Link 02/2022
1	Ivermectin (Mectizan)FDA Link 02/2022
1	Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)IBA 01/2022
1	Calcitonin Gene-Related PeptideIBA 01/2022
1	Calcitonin Gene-Related Peptide Receptor AntagonistsIBA 01/2022
1	ProcalcitoninIBA 01/2022
1	olcegepantIBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	Hormones (Hormone)IBA 12/2020
1	sodium thiosulfate FDA Link 01/2020
1	Oxytocin Receptors (Oxytocin Receptor)IBA 01/2020
1	Vasoconstrictor AgentsIBA 10/2019
1	Troponin IIBA 10/2019
1	InterleukinsIBA 10/2019
1	NitrogenIBA 01/2019
1	LipopolysaccharidesIBA 01/2019
1	3-mercaptopyruvate sulphurtransferaseIBA 01/2019
1	ParvalbuminsIBA 11/2018
1	Ethanol (Ethyl Alcohol)IBA 11/2018
1	Neuroprotective AgentsIBA 11/2018
1	sodium sulfideIBA 10/2018
1	Sodium Chloride FDA LinkGeneric 10/2018
1	Blood Glucose (Blood Sugar)IBA 10/2018

Therapy/Procedure

12	Resuscitation 01/2020 - 12/2013
8	Therapeutics 12/2020 - 10/2017
7	Critical Care (Surgical Intensive Care) 01/2020 - 12/2017
6	Artificial Respiration (Mechanical Ventilation) 04/2021 - 05/2016
2	Catheters 01/2017 - 12/2016
1	Tracheostomy 04/2021
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2020
1	Punctures 01/2019
1	Ligation 01/2019
1	Injections 01/2019