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Ellen Weisberg Selected Research

ibrutinib

12/2019A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant BtkC481S mutation in B-cell malignancies.

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Ellen Weisberg Research Topics

Disease

14Leukemia
01/2022 - 06/2002
12Neoplasms (Cancer)
01/2020 - 03/2006
12Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018 - 01/2003
12BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
09/2015 - 01/2002
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
05/2015 - 10/2003
4COVID-19
06/2023 - 08/2020
3Infections
01/2023 - 08/2020
3Philadelphia Chromosome
12/2014 - 10/2003
3Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
05/2010 - 10/2003
3Multiple Myeloma
11/2006 - 09/2002
2Systemic Mastocytosis
11/2019 - 01/2018
2Myeloid Leukemia (Leukemia, Myelocytic)
07/2010 - 01/2003
2Hypereosinophilic Syndrome (Loeffler Endocarditis)
05/2010 - 05/2003
2Blast Crisis (Blast Phase)
05/2007 - 10/2003
1Reinfection
06/2023
1Sarcoma (Soft Tissue Sarcoma)
01/2022
1Inflammation (Inflammations)
01/2022
1Prostatic Neoplasms (Prostate Cancer)
07/2013
1Disease Progression
07/2007
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2006
1Lung Neoplasms (Lung Cancer)
03/2006
1Hematologic Neoplasms (Hematological Malignancy)
10/2003

Drug/Important Bio-Agent (IBA)

14Phosphotransferases (Kinase)IBA
01/2023 - 01/2002
9Imatinib Mesylate (Gleevec)FDA Link
12/2014 - 01/2002
7Tyrosine Kinase InhibitorsIBA
01/2013 - 06/2002
6Proteins (Proteins, Gene)FDA Link
01/2023 - 03/2006
6midostaurinIBA
11/2019 - 06/2002
5Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
05/2016 - 01/2003
3VaccinesIBA
06/2023 - 08/2020
3Antiviral Agents (Antivirals)IBA
06/2023 - 08/2020
3nilotinibFDA Link
12/2014 - 03/2007
3Histone Deacetylases (Histone Deacetylase)IBA
11/2006 - 10/2003
3Histone Deacetylase InhibitorsIBA
11/2006 - 10/2003
2gilteritinibIBA
01/2023 - 11/2019
2Protein Kinases (Protein Kinase)IBA
01/2023 - 12/2008
2Sorafenib (BAY 43-9006)FDA Link
11/2019 - 11/2012
2Drug CombinationsIBA
11/2014 - 07/2007
2Pimozide (Orap)FDA Link
07/2012 - 03/2011
2STAT5 Transcription FactorIBA
07/2012 - 03/2011
2Tyrosine (L-Tyrosine)FDA Link
07/2007 - 01/2003
2Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)IBA
12/2006 - 10/2003
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2005 - 09/2002
2bcr-abl Fusion ProteinsIBA
02/2005 - 10/2003
1AntibodiesIBA
06/2023
1nintedanibIBA
01/2023
11-dodecylpyridoxal (PLD)IBA
01/2023
1RNA (Ribonucleic Acid)IBA
01/2022
1UbiquitinIBA
01/2020
1Ligases (Synthetase)IBA
01/2020
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2020
1Agammaglobulinaemia Tyrosine KinaseIBA
12/2019
1ibrutinibIBA
12/2019
1quizartinibIBA
11/2019
1crenolanibIBA
11/2019
1tyrosine receptor (receptor, tyrosine)IBA
11/2019
1avapritinibIBA
11/2019
1NVP-CGM097IBA
10/2015
1N- (4- methyl- 3- (1- methyl- 7- (6- methylpyridin- 3- ylamino)- 2- oxo- 1,2- dihydropyrimido(4,5- d)pyrimidin- 3(4H)- yl)phenyl)- 3- (trifluoromethyl)benzamideIBA
05/2015
1TOR Serine-Threonine KinasesIBA
01/2015
1Dasatinib (BMS 354825)FDA Link
12/2014
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
11/2014
1AZD 6244IBA
11/2014
1NVP-AEW541IBA
11/2014
1MK 2206IBA
07/2013
1BMX-IN-1IBA
07/2013
1nutlin 3IBA
11/2012
1TriterpenesIBA
07/2010
1EstersIBA
07/2010
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
07/2010
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
07/2010
1bardoxolone methylIBA
07/2010
1Platelet-Derived Growth Factor alpha ReceptorIBA
05/2010
1Adenosine Triphosphate (ATP)IBA
05/2010
1NF-kappa B (NF-kB)IBA
04/2010
1Antineoplastic Agents (Antineoplastics)IBA
04/2010
1LuciferasesIBA
04/2010
1Indicators and Reagents (Reagents)IBA
12/2008
1NVP-AST487IBA
12/2008
1LBW242IBA
07/2007
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
12/2006
1trichostatin A (A 300)IBA
03/2006
1Histones (Histone)IBA
03/2006
1Annexin A5IBA
03/2006
1GelsolinIBA
03/2006
1Sirolimus (Rapamycin)FDA Link
06/2005
1Hydroxamic Acids (Hydroxamic Acid)IBA
10/2003
1Stem Cell FactorIBA
10/2003
1LAQ824IBA
10/2003
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2003
1vatalanib (PTK787)IBA
09/2002
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
09/2002
1NSC 680410IBA
01/2002

Therapy/Procedure

13Therapeutics
01/2023 - 10/2003
1Oral Administration
11/2014