Matthias M Weber Selected Research

Type 2 Diabetes Mellitus (MODY)

1/2017	Effects on α- and β-cell function of sequentially adding empagliflozin and linagliptin to therapy in people with type 2 diabetes previously receiving metformin: An exploratory mechanistic study.
9/2015	Elevated Intact Proinsulin Levels During an Oral Glucose Challenge Indicate Progressive ß-Cell Dysfunction and May Be Predictive for Development of Type 2 Diabetes.
1/2012	Pilot study for the evaluation of morphological and functional changes in retinal blood flow in patients with insulin resistance and/or type 2 diabetes mellitus.
1/2012	Cardiovascular benefits of GLP-1-based herapies in patients with diabetes mellitus type 2: effects on endothelial and vascular dysfunction beyond glycemic control.
7/2010	Pioglitazone in addition to metformin improves erythrocyte deformability in patients with Type 2 diabetes mellitus.
5/2008	Effect of insulin glulisine on microvascular blood flow and endothelial function in the postprandial state.
1/2008	A biomarker concept for assessment of insulin resistance, beta-cell function and chronic systemic inflammation in type 2 diabetes mellitus.
8/2007	Pioglitazone: update on an oral antidiabetic drug with antiatherosclerotic effects.
1/2004	Intact and total proinsulin: new aspects for diagnosis and treatment of type 2 diabetes mellitus and insulin resistance.

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Matthias M Weber Research Topics

Disease

19	Neoplasms (Cancer) 04/2022 - 11/2002
9	Type 2 Diabetes Mellitus (MODY) 01/2017 - 01/2004
8	Neuroendocrine Tumors (Neuroendocrine Tumor) 07/2021 - 01/2006
7	Insulin Resistance 05/2018 - 01/2004
6	Inflammation (Inflammations) 10/2020 - 08/2007
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2021 - 04/2006
3	Neoplasm Metastasis (Metastasis) 10/2020 - 11/2010
3	Diabetes Mellitus 03/2014 - 07/2007
3	Paraganglioma (Paragangliomas) 03/2014 - 07/2008
3	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 01/2010 - 10/2005
2	Residual Neoplasm 02/2022 - 01/2016
2	Disease Progression 02/2022 - 01/2017
2	Hypopituitarism (Sheehan's Syndrome) 01/2018 - 05/2007
2	Gaucher Disease (Gaucher's Disease) 01/2018 - 05/2013
2	Pheochromocytoma 03/2014 - 04/2006
2	Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal) 01/2010 - 10/2005
2	Atherosclerosis 01/2010 - 08/2007
2	Turner Syndrome (Turner's Syndrome) 10/2009 - 01/2004
2	Hypertension (High Blood Pressure) 08/2007 - 01/2006
1	Hypoglycemia (Reactive Hypoglycemia) 04/2022
1	Thyroid Diseases (Thyroid Disease) 11/2021
1	Hypophysitis 11/2021
1	Pituitary Neoplasms (Pituitary Adenoma) 03/2021
1	Malnutrition (Nutritional Deficiencies) 10/2020
1	Hypoparathyroidism 12/2019
1	Hypocalcemia 12/2019
1	Osteoporosis 01/2018
1	Neuroendocrine Carcinoma 01/2018
1	Bone Resorption 01/2018
1	Merkel Cell Carcinoma 01/2018
1	Microsatellite Instability 01/2018
1	Wounds and Injuries (Trauma) 01/2017
1	Diabetic Foot 01/2017
1	Thyroid Neoplasms (Thyroid Cancer) 11/2016
1	Diabetes Insipidus 01/2016
1	Nausea 01/2015
1	Fatigue 01/2015
1	Carcinoid Tumor (Carcinoid) 01/2015
1	Hyperglycemia 01/2015
1	Diabetic Retinopathy (Retinopathy, Diabetic) 03/2014
1	Peripheral Nervous System Diseases (PNS Diseases) 03/2014

Drug/Important Bio-Agent (IBA)

8	Glucose (Dextrose)FDA LinkGeneric 05/2018 - 01/2004
8	Insulin-Like Growth Factor I (IGF-1)IBA 01/2018 - 01/2002
7	Biomarkers (Surrogate Marker)IBA 02/2022 - 08/2007
5	Hormones (Hormone)IBA 12/2017 - 01/2006
4	Insulin (Novolin)FDA Link 04/2022 - 01/2004
4	Somatostatin Receptors (Somatostatin Receptor)IBA 05/2019 - 01/2006
4	Radioisotopes (Radionuclides)IBA 05/2019 - 10/2004
4	Proteins (Proteins, Gene)FDA Link 03/2014 - 11/2002
4	LipidsIBA 05/2013 - 01/2008
3	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 07/2021 - 01/2014
3	Succinate Dehydrogenase (Fumarate Reductase)IBA 03/2014 - 07/2008
3	Insulin-Like Growth Factor II (Somatomedin A)IBA 09/2008 - 01/2002
3	Insulin-Like Growth Factor Binding Protein 3IBA 09/2008 - 01/2002
3	Insulin-Like Growth Factor Binding Protein 2IBA 09/2008 - 01/2002
3	LigandsIBA 04/2006 - 11/2002
2	DNA (Deoxyribonucleic Acid)IBA 02/2022 - 09/2010
2	Immune Checkpoint InhibitorsIBA 11/2021 - 01/2018
2	lanreotide (Somatuline)FDA Link 07/2021 - 01/2017
2	Parathyroid Hormone (Parathormone)IBA 12/2019 - 01/2006
2	Octreotide (Sandostatin)FDA LinkGeneric 12/2017 - 01/2015
2	Metformin (Glucophage)FDA LinkGeneric 01/2017 - 07/2010
2	ProinsulinIBA 09/2015 - 01/2004
2	Retinaldehyde (Retinal)IBA 03/2014 - 01/2012
2	oxidized low density lipoproteinIBA 05/2013 - 06/2011
2	Blood Glucose (Blood Sugar)IBA 01/2012 - 04/2006
2	RNA (Ribonucleic Acid)IBA 09/2010 - 04/2006
2	Pioglitazone (Actos)FDA Link 07/2010 - 08/2007
2	Insulin-Like Growth Factor Binding ProteinsIBA 09/2008 - 01/2002
2	Growth Hormone (Somatotropin)IBA 05/2007 - 01/2004
2	Messenger RNA (mRNA)IBA 04/2006 - 11/2002
2	IGF Type 1 Receptor (IGF 1 Receptor)IBA 04/2006 - 11/2002
2	Insulin-Like PeptidesIBA 11/2002 - 01/2002
1	Cell-Free Nucleic AcidsIBA 02/2022
1	Chromogranin AIBA 02/2022
1	cyclopropapyrroloindoleIBA 11/2021
1	ArtesunateIBA 12/2020
1	Histones (Histone)IBA 10/2020
1	Nicotine FDA Link 10/2020
1	Peptide Receptors (Peptide Receptor)IBA 05/2019
1	dapagliflozinIBA 05/2018
1	avelumabIBA 01/2018
1	Estrogens (Estrogen)FDA Link 01/2018
1	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2018
1	OsteoprotegerinIBA 01/2018
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 01/2018
1	IsotopesIBA 12/2017
1	Phosphotransferases (Kinase)IBA 12/2017
1	LinagliptinIBA 01/2017
1	empagliflozinIBA 01/2017
1	IodineIBA 11/2016
1	pasireotideIBA 01/2015

Therapy/Procedure

13	Therapeutics 03/2021 - 01/2004
2	Radiotherapy 03/2021 - 12/2017
2	Drug Therapy (Chemotherapy) 05/2019 - 01/2018
2	Enzyme Replacement Therapy 01/2018 - 05/2013
1	Nutritional Support (Artificial Feeding) 10/2020
1	Immunotherapy 01/2018
1	Surgical Amputation (Amputations) 01/2017
1	Thyroidectomy 11/2016