Shixuan Wang Selected Research

Small Interfering RNA (siRNA)

1/2021	Biocompatible AIEgen/p-glycoprotein siRNA@reduction-sensitive paclitaxel polymeric prodrug nanoparticles for overcoming chemotherapy resistance in ovarian cancer.
11/2020	Modular Peptide Probe for Pre/Intra/Postoperative Therapeutic to Reduce Recurrence in Ovarian Cancer.
12/2013	Abrogation of constitutive Stat3 activity circumvents cisplatin resistant ovarian cancer.
5/2013	Silencing of the STAT3 signaling pathway reverses the inherent and induced chemoresistance of human ovarian cancer cells.
6/2012	Suppression of EphB4 improves the inhibitory effect of mTOR shRNA on the biological behaviors of ovarian cancer cells by down-regulating Akt phosphorylation.
3/2010	Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1alpha.
11/2008	Effect of tumor suppressor gene PTEN on the resistance to cisplatin in human ovarian cancer cell lines and related mechanisms.
11/2008	Short hairpin RNA targeting c-FLIP sensitizes human cervical adenocarcinoma Hela cells to chemotherapy and radiotherapy.
3/2008	Ezrin silencing by small hairpin RNA reverses metastatic behaviors of human breast cancer cells.
2/2008	RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53.

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Shixuan Wang Research Topics

Disease

89	Neoplasms (Cancer) 11/2023 - 05/2002
45	Uterine Cervical Neoplasms (Cancer of the Cervix) 06/2023 - 09/2005
40	Ovarian Neoplasms (Ovarian Cancer) 10/2023 - 04/2002
21	Neoplasm Metastasis (Metastasis) 01/2023 - 05/2002
12	Carcinogenesis 12/2020 - 07/2005
10	Carcinoma (Carcinomatosis) 07/2014 - 10/2005
9	Breast Neoplasms (Breast Cancer) 12/2021 - 01/2006
7	Infertility (Sterility) 01/2023 - 01/2015
5	Fibrosis (Cirrhosis) 01/2023 - 01/2014
5	Acute Kidney Injury (Acute Renal Failure) 01/2023 - 10/2013
5	Autosomal Recessive Polycystic Kidney (Polycystic Kidney Disease, Infantile, Type I) 01/2014 - 03/2004
5	Lymphatic Metastasis 10/2013 - 03/2008
4	Infections 01/2021 - 08/2007
4	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2018 - 03/2017
4	Ovarian Epithelial Carcinoma 11/2008 - 04/2003
3	Hemorrhage 11/2023 - 12/2014
3	Hypoxia (Hypoxemia) 12/2021 - 02/2008
3	Residual Neoplasm 06/2021 - 04/2003
3	Papillomavirus Infections 01/2015 - 08/2007
3	Retinoblastoma (Glioblastoma, Retinal) 01/2015 - 08/2007
3	Prostatic Neoplasms (Prostate Cancer) 09/2008 - 06/2007
2	Primary Ovarian Insufficiency 01/2024 - 10/2022
2	Endometrial Neoplasms (Endometrial Cancer) 01/2024 - 01/2023
2	Leiomyoma (Uterine Fibroids) 01/2024 - 10/2021
2	Disseminated Intravascular Coagulation 01/2024 - 11/2023
2	Starvation 01/2024 - 04/2011
2	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2024 - 01/2021
2	Aneuploidy (Aneuploid) 12/2023 - 11/2011
2	Hereditary Sensory and Motor Neuropathy (Dejerine Sottas Disease) 10/2023 - 12/2022
2	COVID-19 01/2021 - 09/2020
2	Inflammation (Inflammations) 01/2021 - 01/2014
2	Autoimmune Diseases (Autoimmune Disease) 11/2017 - 08/2017
2	Endometriosis 01/2017 - 01/2013
2	Virus Diseases (Viral Diseases) 01/2015 - 12/2009

Drug/Important Bio-Agent (IBA)

35	Proteins (Proteins, Gene)FDA Link 10/2023 - 03/2004
18	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 11/2002
11	Peptides (Polypeptides)IBA 01/2021 - 01/2006
11	Small Interfering RNA (siRNA)IBA 01/2021 - 02/2008
9	Biomarkers (Surrogate Marker)IBA 12/2021 - 11/2010
8	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 01/2007
7	1-phenyl-3,3-dimethyltriazene (PDT)IBA 10/2023 - 11/2020
7	CytokinesIBA 09/2022 - 01/2009
7	Caspase 3 (Caspase-3)IBA 01/2013 - 11/2002
6	DNA (Deoxyribonucleic Acid)IBA 12/2023 - 04/2002
6	PlatinumIBA 01/2023 - 05/2013
5	Fibronectins (Fibronectin)IBA 10/2023 - 02/2008
5	Therapeutic UsesIBA 06/2022 - 08/2011
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 05/2002
5	VaccinesIBA 02/2020 - 12/2009
4	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2023 - 02/2008
4	EnzymesIBA 12/2021 - 02/2006
4	Messenger RNA (mRNA)IBA 06/2021 - 01/2006
4	Histone Deacetylase InhibitorsIBA 06/2017 - 09/2005
4	Phosphotransferases (Kinase)IBA 01/2015 - 01/2005
4	SurvivinIBA 12/2013 - 07/2005
4	VimentinIBA 10/2013 - 06/2007
4	Cadherins (E-Cadherin)IBA 01/2013 - 03/2008
4	Complementary DNA (cDNA)IBA 11/2011 - 05/2002
3	ParaffinIBA 01/2024 - 04/2006
3	AntigensIBA 11/2023 - 02/2005
3	taxaneIBA 01/2023 - 01/2015
3	Hormones (Hormone)IBA 10/2022 - 05/2015
3	Estradiol (Delestrogen)FDA LinkGeneric 01/2021 - 05/2015
3	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2021 - 08/2005
3	Inosine Triphosphate (ITP)IBA 01/2018 - 08/2017
3	trichostatin A (A 300)IBA 06/2017 - 09/2005
3	theasinensin AIBA 06/2017 - 09/2005
3	Antineoplastic Agents (Antineoplastics)IBA 02/2014 - 08/2005
3	OligonucleotidesIBA 01/2012 - 12/2004
3	Antisense OligonucleotidesIBA 07/2005 - 04/2002
2	Zishen YutaiIBA 01/2024 - 10/2022
2	Dacarbazine (DIC)FDA LinkGeneric 01/2024 - 11/2023
2	Photosensitizing Agents (Photosensitizers)IBA 10/2023 - 04/2023
2	IntegrinsIBA 10/2023 - 01/2006
2	Semaphorins (Semaphorin)IBA 01/2023 - 12/2021
2	SteroidsIBA 10/2022 - 01/2013
2	Taxoids (Taxanes)IBA 01/2022 - 01/2015
2	Neoplasm Antigens (Tumor Antigens)IBA 12/2021 - 06/2021
2	Telomerase (Telomerase Reverse Transcriptase)IBA 06/2021 - 08/2007
2	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 02/2006
2	Interleukin-10 (Interleukin 10)IBA 01/2021 - 12/2009
2	Metformin (Glucophage)FDA LinkGeneric 07/2020 - 01/2020
2	Anti-Mullerian HormoneIBA 04/2020 - 05/2015
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 02/2020 - 12/2009
2	MicroRNAs (MicroRNA)IBA 03/2018 - 01/2016
2	Bortezomib (Velcade)FDA Link 06/2017 - 05/2011
2	Proteasome InhibitorsIBA 06/2017 - 05/2011
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2015 - 12/2009
2	Oncogene Proteins (Oncogene Protein)IBA 01/2015 - 01/2013

Therapy/Procedure

33	Therapeutics 03/2023 - 01/2006
21	Drug Therapy (Chemotherapy) 03/2023 - 04/2003
11	Neoadjuvant Therapy 01/2021 - 10/2012
9	Photochemotherapy (Photodynamic Therapy) 04/2023 - 01/2020
6	Immunotherapy 10/2023 - 03/2010
5	Hysterectomy 01/2024 - 03/2013
4	Lymph Node Excision (Lymph Node Dissection) 11/2022 - 04/2003
3	Photothermal Therapy 12/2021 - 06/2021
3	Precision Medicine 12/2021 - 12/2020
3	Radiotherapy 01/2013 - 11/2008
2	Adjuvant Chemotherapy 01/2018 - 01/2013