Hong-Yang Wang Selected Research

Carcinogenesis

1/2021	4-phenylbutyric acid promotes hepatocellular carcinoma via initiating cancer stem cells through activation of PPAR-α.
1/2020	RPB5-Mediating Protein Promotes Cholangiocarcinoma Tumorigenesis and Drug Resistance by Competing With NRF2 for KEAP1 Binding.
1/2017	Choline Kinase α Mediates Interactions Between the Epidermal Growth Factor Receptor and Mechanistic Target of Rapamycin Complex 2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression.
10/2015	A splicing variant of Merlin promotes metastasis in hepatocellular carcinoma.
10/2013	p53 promotes inflammation-associated hepatocarcinogenesis by inducing HMGB1 release.
4/2012	RACK1 suppresses gastric tumorigenesis by stabilizing the β-catenin destruction complex.
1/2012	Hepatitis B virus X (HBx) induces tumorigenicity of hepatic progenitor cells in 3,5-diethoxycarbonyl-1,4-dihydrocollidine-treated HBx transgenic mice.
12/2010	Dysregulation of β-catenin by hepatitis B virus X protein in HBV-infected human hepatocellular carcinomas.
10/2010	Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents.
11/2009	p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hong-Yang Wang Research Topics

Disease

71	Neoplasms (Cancer) 01/2024 - 02/2000
64	Hepatocellular Carcinoma (Hepatoma) 01/2024 - 07/2002
15	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2004
15	Liver Neoplasms (Liver Cancer) 01/2022 - 02/2000
14	Cholangiocarcinoma 05/2024 - 10/2005
13	Carcinogenesis 01/2021 - 05/2003
8	Inflammation (Inflammations) 01/2019 - 10/2010
7	Fibrosis (Cirrhosis) 07/2023 - 02/2003
5	Hypoxia (Hypoxemia) 06/2023 - 01/2011
5	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 08/2002
5	Hepatitis B 10/2011 - 05/2003
4	Carcinoma (Carcinomatosis) 02/2013 - 08/2002
3	Non-alcoholic Fatty Liver Disease 11/2022 - 11/2011
3	Necrosis 01/2021 - 01/2019
2	Starvation 01/2022 - 08/2011
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2022 - 01/2016
2	Deafness (Deaf Mutism) 08/2021 - 03/2017
2	Infections 06/2017 - 12/2015
2	Thrombosis (Thrombus) 10/2015 - 08/2002
2	Liver Diseases (Liver Disease) 12/2014 - 02/2003
2	Thymoma (Thymic Carcinoma) 12/2013 - 01/2011
2	Fatty Liver 11/2011 - 01/2010
2	Melanoma (Melanoma, Malignant) 12/2009 - 06/2008
1	Primary Ovarian Insufficiency 05/2023
1	Alcoholic Hepatitis 01/2023

Drug/Important Bio-Agent (IBA)

21	Proteins (Proteins, Gene)FDA Link 06/2023 - 07/2002
11	Biomarkers (Surrogate Marker)IBA 01/2023 - 10/2005
9	CateninsIBA 01/2024 - 06/2008
8	AntigensIBA 02/2013 - 05/2003
7	beta CateninIBA 01/2023 - 12/2002
7	Sorafenib (BAY 43-9006)FDA Link 01/2020 - 02/2011
6	MicroRNAs (MicroRNA)IBA 12/2013 - 02/2009
5	Phosphoric Monoester Hydrolases (Phosphatases)IBA 05/2024 - 04/2015
5	Glucose (Dextrose)FDA LinkGeneric 12/2022 - 01/2016
5	RNA (Ribonucleic Acid)IBA 12/2022 - 02/2005
5	Phosphotransferases (Kinase)IBA 01/2021 - 01/2011
5	CarcinogensIBA 01/2020 - 10/2010
4	TensinsIBA 12/2023 - 04/2015
4	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023 - 10/2011
4	EnzymesIBA 11/2022 - 02/2000
4	Fatty Acids (Saturated Fatty Acids)IBA 11/2022 - 02/2016
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2022 - 09/2005
4	Cadherins (E-Cadherin)IBA 01/2022 - 12/2002
4	CytokinesIBA 01/2020 - 09/2012
4	LigandsIBA 01/2018 - 06/2007
4	HMGB1 Protein (HMG1)IBA 10/2014 - 12/2009
4	AgarIBA 04/2012 - 05/2003
3	Cell-Free Nucleic AcidsIBA 01/2024 - 01/2021
3	Proteasome InhibitorsIBA 01/2023 - 01/2020
3	Mechanistic Target of Rapamycin Complex 2IBA 01/2022 - 04/2015
3	Messenger RNA (mRNA)IBA 01/2021 - 02/2000
3	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 01/2021 - 10/2010
3	alpha-Fetoproteins (alpha-Fetoprotein)IBA 12/2019 - 03/2009
3	ErbB Receptors (EGF Receptor)IBA 01/2017 - 12/2013
3	Hepatitis B Surface Antigens (HBsAg)FDA Link 12/2015 - 01/2010
3	NF-kappa B (NF-kB)IBA 11/2014 - 11/2011
3	EndotoxinsIBA 10/2012 - 10/2010
3	IsotopesIBA 02/2012 - 04/2004
3	Epithelial Cell Adhesion MoleculeIBA 01/2012 - 03/2009
2	Bortezomib (Velcade)FDA Link 05/2024 - 01/2021
2	UbiquitinIBA 01/2023 - 12/2017
2	Ribose (D-Ribose)IBA 12/2022 - 11/2022
2	NucleotidesIBA 11/2022 - 01/2018
2	SuspensionsIBA 05/2022 - 10/2011
2	AndrogensIBA 01/2022 - 06/2017
2	Transcription Factors (Transcription Factor)IBA 01/2022 - 10/2010
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2022 - 06/2008
2	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 01/2020
2	CaspasesIBA 01/2020 - 01/2019
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 10/2010
2	ChemokinesIBA 01/2020 - 01/2018
2	CarbohydratesIBA 01/2019 - 02/2009
2	Keratin-19 (Keratin 19)IBA 12/2017 - 01/2004
2	Small Interfering RNA (siRNA)IBA 09/2015 - 08/2011
2	Tyrosine (L-Tyrosine)FDA Link 09/2015 - 09/2004
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 04/2015 - 02/2003
2	Cytochrome P-450 CYP3AIBA 04/2015 - 02/2003
2	Hepatocyte Nuclear FactorsIBA 11/2014 - 10/2011
2	Membrane Proteins (Integral Membrane Proteins)IBA 08/2014 - 05/2014
2	Protein Isoforms (Isoforms)IBA 12/2013 - 02/2003
2	Phosphatidylinositols (Phosphatidylinositol)IBA 12/2013 - 01/2011
2	Tumor Biomarkers (Tumor Markers)IBA 02/2013 - 03/2005
2	Anti-Bacterial Agents (Antibiotics)IBA 09/2012 - 10/2010
2	Toll-Like Receptor 4IBA 09/2012 - 11/2011
2	Alanine Transaminase (SGPT)IBA 11/2011 - 01/2010
2	Beclin-1IBA 10/2011 - 08/2011
2	Oncogene Proteins (Oncogene Protein)IBA 10/2011 - 11/2009
2	ProteomeIBA 01/2008 - 04/2004
2	Cyclin D1IBA 05/2006 - 05/2005
1	Gemcitabine FDA Link 12/2023
1	NucleosidesIBA 12/2023
1	Caspase 8 (Caspase-8)IBA 05/2023
1	Death Domain ReceptorsIBA 05/2023
1	Tyrosine Kinase InhibitorsIBA 01/2023

Therapy/Procedure

19	Therapeutics 01/2022 - 06/2008
4	Lasers (Laser) 01/2020 - 01/2004
3	Immunotherapy 01/2022 - 01/2019
2	Oral Administration 07/2023 - 01/2021
2	Drug Therapy (Chemotherapy) 01/2021 - 06/2008
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 10/2014 - 11/2011