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Gail Walkinshaw Selected Research

Cholesterol

1/2022Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism.
1/2020HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD.
4/2016Hypoxia-Inducible Factor Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis.

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Gail Walkinshaw Research Topics

Disease

15Hypoxia (Hypoxemia)
01/2020 - 05/2009
5Inflammation (Inflammations)
01/2022 - 04/2016
4Insulin Resistance
01/2022 - 10/2014
3Ischemia
01/2014 - 07/2009
2Anemia
01/2020 - 04/2016
2Obesity
04/2016 - 10/2014
1Hypertrophy
01/2022
1Body Weight (Weight, Body)
01/2022
1Hyperglycemia
01/2022
1Iron Deficiencies
01/2020
1Chronic Renal Insufficiency
01/2020
1Non-alcoholic Fatty Liver Disease
01/2020
1Alcoholic Fatty Liver
01/2019
1Fatty Liver
01/2019
1Atherosclerosis
04/2016
1Atherosclerotic Plaque (Atheroma)
04/2016
1Weight Gain
04/2016
1Edema (Dropsy)
01/2014
1Ischemic Stroke
01/2014
1Brain Ischemia (Cerebral Ischemia)
01/2014
1Brain Injuries (Brain Injury)
09/2013
1Brain Diseases (Brain Disorder)
09/2013
1Wounds and Injuries (Trauma)
09/2013
1Stroke (Strokes)
09/2013
1Epilepsy (Aura)
09/2013

Drug/Important Bio-Agent (IBA)

7Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
12/2019 - 10/2012
6Transcription Factors (Transcription Factor)IBA
01/2020 - 07/2009
5Oxygen (Dioxygen)IBA
01/2020 - 05/2009
5FG-4497IBA
04/2016 - 07/2009
3Messenger RNA (mRNA)IBA
01/2022 - 07/2012
3CholesterolIBA
01/2022 - 04/2016
3Proteins (Proteins, Gene)FDA Link
01/2022 - 09/2013
3Glucose (Dextrose)FDA LinkGeneric
04/2016 - 01/2014
2Prolyl-Hydroxylase InhibitorsIBA
01/2020 - 09/2013
2ErythropoietinFDA Link
01/2020 - 01/2014
2EnzymesIBA
12/2019 - 01/2017
2cobaltous chloride (cobalt(II)chloride)IBA
04/2015 - 05/2009
2Neuroprotective AgentsIBA
09/2013 - 07/2012
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
01/2022
1Leucine (L-Leucine)FDA Link
01/2022
1Triglycerides (Triacylglycerol)IBA
01/2022
1Small Interfering RNA (siRNA)IBA
01/2022
1roxadustatIBA
01/2020
1Choline (Choline Chloride)IBA
01/2020
1FructoseIBA
01/2020
1Hormones (Hormone)IBA
01/2020
1IronIBA
01/2020
1MetalsIBA
01/2020
1Methionine (L-Methionine)FDA Link
01/2020
1Peptidoglycan (Murein)IBA
01/2020
1Polysaccharides (Glycans)IBA
01/2020
1Cytochromes b (Cytochrome b)IBA
01/2020
1HepcidinsIBA
01/2020
1Ethanol (Ethyl Alcohol)IBA
01/2019
1Lipoproteins (Lipoprotein)IBA
01/2019
1AntioxidantsIBA
01/2019
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2017
1oxidized low density lipoproteinIBA
04/2016
1LDL Lipoproteins (beta Lipoproteins)IBA
04/2016
1AutoantibodiesIBA
04/2016
1LDL Receptors (LDL Receptor)IBA
04/2016
1CopperIBA
04/2016
1LipidsIBA
04/2016
1Endothelins (Endothelin)IBA
04/2015
1MimosineIBA
04/2015
1Endothelin-Converting EnzymesIBA
04/2015
1IsoenzymesIBA
10/2014
1OccludinIBA
01/2014
1Hypoxia-Inducible Factor-Proline DioxygenasesIBA
01/2014
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2014
1Tight Junction ProteinsIBA
01/2014
1activin AIBA
09/2013
1Activins (Activin)IBA
09/2013
1Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2013
1Enzyme Inhibitors (Inhibitors, Enzyme)IBA
01/2013
1Mixed Function Oxygenases (Monooxygenases)IBA
07/2012
1Hemeproteins (Heme Protein)IBA
07/2012
1NeuroglobinIBA
07/2012
1dimethyloxallyl glycineIBA
05/2009
1Deferoxamine (Desferal)FDA LinkGeneric
05/2009
1Ciclopirox (Loprox)FDA LinkGeneric
05/2009

Therapy/Procedure

2Therapeutics
01/2019 - 10/2014
1Nephrectomy
01/2020