Ihomi Usami Selected Research

Neoplasms (Cancer)

12/2021	Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment.
11/2017	A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth in vivo.
1/2015	Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction.
9/2013	Intervenolin, a new antitumor compound with anti-Helicobacter pylori activity, from Nocardia sp. ML96-86F2.
5/2010	NBRI17671, a new antitumor compound, produced by Acremonium sp. CR17671.
3/2010	Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis.
1/2009	Phthoxazolin A inhibits prostate cancer growth by modulating tumor-stromal cell interactions.
10/2002	Hygrolidin induces p21 expression and abrogates cell cycle progression at G1 and S phases.

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Ihomi Usami Research Topics

Disease

8	Neoplasms (Cancer) 12/2021 - 10/2002
3	Prostatic Neoplasms (Prostate Cancer) 11/2017 - 10/2006
3	Neoplasm Metastasis (Metastasis) 04/2015 - 03/2010
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 04/2015
1	Stomach Neoplasms (Stomach Cancer) 01/2015
1	Colorectal Neoplasms (Colorectal Cancer) 09/2013
1	Cachexia 10/2006
1	Colonic Neoplasms (Colon Cancer) 10/2002

Drug/Important Bio-Agent (IBA)

2	intervenolinIBA 12/2021 - 09/2013
2	Interleukin-6 (Interleukin 6)IBA 01/2015 - 10/2006
1	Proteins (Proteins, Gene)FDA Link 12/2021
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2021
1	Lactic Acid (Lactate)FDA LinkGeneric 12/2021
1	Complement System Proteins (Complement)IBA 11/2017
1	adenovirus receptorIBA 11/2017
1	Protein Sorting Signals (Signal Peptide)IBA 11/2017
1	Monoclonal AntibodiesIBA 11/2017
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 04/2015
1	Dinoprostone (PGE2)FDA Link 01/2015
1	Cadherins (E-Cadherin)IBA 01/2015
1	Mitogen-Activated Protein KinasesIBA 05/2010
1	HMGB1 Protein (HMG1)IBA 05/2010
1	Receptor for Advanced Glycation End ProductsIBA 05/2010
1	cytostatinIBA 03/2010
1	rubratoxinsIBA 03/2010
1	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 03/2010
1	inthomycin BIBA 01/2009
1	phthoxazolinIBA 01/2009
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2009
1	AndrogensIBA 10/2006
1	CytokinesIBA 10/2006
1	hygrolidinIBA 10/2002

Therapy/Procedure

1	Immunotherapy 11/2017
1	Transplantation 04/2015