Sean Uryu Selected Research

Carcinoma (Carcinomatosis)

8/2014	FAK Inhibition disrupts a β5 integrin signaling axis controlling anchorage-independent ovarian carcinoma growth.
6/2013	Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression.
5/2010	PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.

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Sean Uryu Research Topics

Disease

11	Neoplasms (Cancer) 01/2024 - 05/2010
4	Ovarian Neoplasms (Ovarian Cancer) 01/2019 - 06/2013
3	Breast Neoplasms (Breast Cancer) 10/2023 - 05/2010
3	Carcinoma (Carcinomatosis) 08/2014 - 05/2010
2	Ascites 08/2014 - 05/2010
2	Neoplasm Metastasis (Metastasis) 01/2014 - 05/2010
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2020
1	Neurofibromatosis 2 (Neurofibromatosis Type II) 07/2014
1	Mesothelioma 07/2014
1	Melanoma (Melanoma, Malignant) 01/2014
1	Inflammation (Inflammations) 06/2012
1	Splenomegaly 05/2010

Drug/Important Bio-Agent (IBA)

4	Tyrosine (L-Tyrosine)FDA Link 01/2019 - 05/2010
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 07/2014
3	Focal Adhesion Protein-Tyrosine KinasesIBA 07/2014 - 06/2013
2	Histones (Histone)IBA 10/2023 - 01/2020
2	Phosphotransferases (Kinase)IBA 03/2015 - 01/2014
2	Proteins (Proteins, Gene)FDA Link 03/2015 - 08/2014
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 08/2014 - 06/2013
2	Messenger RNA (mRNA)IBA 08/2014 - 06/2013
2	Drinking WaterIBA 05/2010 - 05/2010
2	PND 1186IBA 05/2010 - 05/2010
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2024
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 10/2023
1	Lysine AcetyltransferasesIBA 10/2023
1	Estrogens (Estrogen)FDA Link 10/2023
1	RNA Polymerase II (RNA Polymerase B)IBA 10/2023
1	PF06821497IBA 01/2020
1	Enhancer of Zeste Homolog 2 ProteinIBA 01/2020
1	Lysine (L-Lysine)FDA Link 01/2020
1	PlatinumIBA 01/2019
1	Aldehyde DehydrogenaseIBA 01/2019
1	CateninsIBA 01/2019
1	AgarIBA 08/2014
1	OsteopontinIBA 08/2014
1	IntegrinsIBA 08/2014
1	Neurofibromin 2 (Merlin)IBA 07/2014
1	Small Interfering RNA (siRNA)IBA 07/2014
1	cadherin 5IBA 01/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2014
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 06/2012
1	Caspase 3 (Caspase-3)IBA 05/2010
1	CytokinesIBA 05/2010
1	Interleukin-6 (Interleukin 6)IBA 05/2010
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2010

Therapy/Procedure

2	Therapeutics 01/2024 - 10/2023
1	Drug Therapy (Chemotherapy) 01/2019
1	Adjuvant Chemotherapy 01/2019
1	Oral Administration 05/2010