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Toshihide Ueno Selected Research

Protein-Tyrosine Kinases (Tyrosine Kinase)

2/2024The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma.
4/2021Identification of a Novel MAN1A1-ROS1 Fusion Gene Through mRNA-based Screening for Tyrosine Kinase Gene Aberrations in a Patient with Leiomyosarcoma.
10/2020Nanostring-based screening for tyrosine kinase fusions in inflammatory myofibroblastic tumors.
10/2010EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors.
5/2009KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer.
12/2008A mouse model for EML4-ALK-positive lung cancer.
7/2008Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer.

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Toshihide Ueno Research Topics

Disease

52Neoplasms (Cancer)
04/2024 - 07/2008
7Lung Neoplasms (Lung Cancer)
04/2024 - 07/2008
7Carcinogenesis
04/2024 - 12/2008
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 07/2008
4Colorectal Neoplasms (Colorectal Cancer)
02/2024 - 01/2019
4Sarcoma (Soft Tissue Sarcoma)
01/2023 - 02/2013
4Neoplasm Metastasis (Metastasis)
01/2021 - 09/2019
3Carcinoma (Carcinomatosis)
11/2022 - 12/2015
3Breast Neoplasms (Breast Cancer)
11/2021 - 08/2015
3Stomach Neoplasms (Stomach Cancer)
01/2021 - 05/2012
3Microsatellite Instability
01/2021 - 01/2019
2Glioma (Gliomas)
02/2024 - 01/2022
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2023 - 07/2020
2Melanoma (Melanoma, Malignant)
11/2021 - 01/2021
2Leukemia
07/2020 - 01/2012
1Tuberous Sclerosis (Bourneville's Disease)
04/2024
1Lymphangioleiomyomatosis (Lymphangiomyomatosis)
04/2024
1Thymoma (Thymic Carcinoma)
04/2024
1Disease Progression
04/2024
1Oligodendroglioma
02/2024
1Glioblastoma (Glioblastoma Multiforme)
02/2024
1Astrocytoma (Pilocytic Astrocytoma)
02/2024
1Hypoxia (Hypoxemia)
01/2022
1Leiomyosarcoma
04/2021
1Neurofibrosarcoma (MPNST)
04/2021
1Ascites
01/2021
1Brain Neoplasms (Brain Tumor)
01/2021
1Lymphatic Metastasis
01/2021
1Lymphoma (Lymphomas)
12/2020
1Adenomyosis
12/2019
1Endometriosis
12/2019
1Adenocarcinoma of Lung
09/2019

Drug/Important Bio-Agent (IBA)

11RNA (Ribonucleic Acid)IBA
02/2024 - 01/2016
10Phosphotransferases (Kinase)IBA
04/2024 - 07/2008
9Biomarkers (Surrogate Marker)IBA
02/2024 - 09/2019
8Proteins (Proteins, Gene)FDA Link
01/2021 - 12/2008
7Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
02/2024 - 07/2008
5Tyrosine Kinase InhibitorsIBA
04/2024 - 01/2020
5Immune Checkpoint InhibitorsIBA
02/2024 - 01/2020
5Complementary DNA (cDNA)IBA
10/2013 - 01/2010
3DNA (Deoxyribonucleic Acid)IBA
02/2024 - 04/2019
3Formaldehyde (Formol)FDA Link
12/2021 - 04/2019
3ParaffinIBA
12/2021 - 04/2019
3Protein Isoforms (Isoforms)IBA
11/2021 - 07/2008
3Messenger RNA (mRNA)IBA
04/2021 - 01/2010
2Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA
12/2023 - 11/2020
2Programmed Cell Death 1 ReceptorIBA
01/2022 - 11/2020
2LigandsIBA
11/2021 - 11/2020
2Tyrosine (L-Tyrosine)FDA Link
04/2021 - 01/2021
2Transcription Factors (Transcription Factor)IBA
07/2020 - 01/2016
2osimertinibIBA
01/2020 - 10/2018
2Progesterone Receptors (Progesterone Receptor)IBA
12/2019 - 06/2017
2Monomeric GTP-Binding ProteinsIBA
09/2019 - 02/2013
2NucleotidesIBA
09/2019 - 04/2019
2MicroRNAs (MicroRNA)IBA
08/2015 - 07/2015
1lipoarabinomannan (LAM)IBA
04/2024
1lenvatinibIBA
04/2024
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
02/2024
1NivolumabIBA
02/2024
1TAS-116IBA
02/2024
1regorafenibIBA
02/2024
1SOX9 Transcription FactorIBA
11/2023
1Calcibiotic Root Canal SealerIBA
10/2023
1milademetanIBA
01/2023
1MAP Kinase Kinase 1IBA
01/2023
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2022
1Glucose (Dextrose)FDA LinkGeneric
01/2022
1Mechanistic Target of Rapamycin Complex 1IBA
01/2022
1Therapeutic UsesIBA
01/2022
1CateninsIBA
01/2022
1Lactic Acid (Lactate)FDA LinkGeneric
01/2022
1Cell-Free Nucleic AcidsIBA
10/2021
1Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
07/2021
1Indicators and Reagents (Reagents)IBA
04/2021
1GelsIBA
01/2021
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2021
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2021
1HydrogelsIBA
01/2021
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2021
1phosphatidyl-N-monomethylaminoethanolIBA
01/2021
1Calcium Channels (Calcium Channel)IBA
01/2021
1OsteopontinIBA
01/2021
1HexokinaseIBA
12/2020
1Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)IBA
11/2020
1tyrosine receptor (receptor, tyrosine)IBA
11/2020
1pazopanibFDA Link
11/2020
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
11/2020
1Insulin (Novolin)FDA Link
01/2020
1Nonesterified Fatty Acids (NEFA)IBA
01/2020
1dienogestFDA Link
12/2019
1Progestins (Progestagens)IBA
12/2019
1A-Form DNA (A-DNA)IBA
09/2019
1MucinsIBA
09/2019

Therapy/Procedure

14Therapeutics
01/2022 - 08/2015
4Immunotherapy
02/2024 - 11/2021
3Radiotherapy
01/2021 - 11/2020
3Drug Therapy (Chemotherapy)
01/2021 - 11/2020
2Molecular Targeted Therapy
01/2022 - 01/2022
2Precision Medicine
11/2020 - 04/2019
1Lasers (Laser)
01/2022