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Terrence M Tumpey Selected Research

Vaccines

1/2019Repeated vaccination against matched H3N2 influenza virus gives less protection than single vaccination in ferrets.
1/2019Heterologous prime-boost with A(H5N1) pandemic influenza vaccines induces broader cross-clade antibody responses than homologous prime-boost.
10/2018Influence of Immune Priming and Egg Adaptation in the Vaccine on Antibody Responses to Circulating A(H1N1)pdm09 Viruses After Influenza Vaccination in Adults.
1/2018Antigenically Diverse Swine Origin H1N1 Variant Influenza Viruses Exhibit Differential Ferret Pathogenesis and Transmission Phenotypes.
1/2018Multi-clade H5N1 virus-like particles: Immunogenicity and protection against H5N1 virus and effects of beta-propiolactone.
11/2017Pathogenicity testing of influenza candidate vaccine viruses in the ferret model.
1/2017Neuraminidase-based recombinant virus-like particles protect against lethal avian influenza A(H5N1) virus infection in ferrets.
1/2017Stockpiled pre-pandemic H5N1 influenza virus vaccines with AS03 adjuvant provide cross-protection from H5N2 clade 2.3.4.4 virus challenge in ferrets.
1/2017An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial.
10/2016Mono- and quadri-subtype virus-like particles (VLPs) containing H10 subtype elicit protective immunity to H10 influenza in a ferret challenge model.
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Terrence M Tumpey Research Topics

Disease

77Human Influenza (Influenza)
02/2024 - 08/2002
65Infections
12/2022 - 08/2002
30Influenza in Birds (Avian Flu)
01/2019 - 01/2004
13Virus Diseases (Viral Diseases)
01/2017 - 08/2002
4Weight Loss (Weight Reduction)
05/2016 - 05/2010
3Orthomyxoviridae Infections
01/2019 - 11/2009
3Inflammation (Inflammations)
05/2013 - 08/2010
2Conjunctivitis
01/2018 - 03/2012
2Communicable Diseases (Infectious Diseases)
03/2013 - 04/2010
2Pneumonia (Pneumonitis)
10/2010 - 12/2005
2Lymphopenia (Lymphocytopenia)
05/2010 - 10/2008
1Respiratory Tract Diseases (Respiratory Tract Disease)
01/2018
1Respiratory Tract Infections (Respiratory Tract Infection)
09/2014
1Hemolysis
04/2014
1Lung Diseases (Lung Disease)
05/2013
1Acute Lung Injury
01/2012
1Sneezing
05/2011
1Acute-Phase Reaction
12/2010
1Disease Progression
11/2010
1Cytokine Release Syndrome
10/2009
1Leukopenia
10/2008

Drug/Important Bio-Agent (IBA)

42VaccinesIBA
01/2019 - 07/2003
25Hemagglutinins (Hemagglutinin)IBA
01/2019 - 08/2002
23Proteins (Proteins, Gene)FDA Link
10/2022 - 08/2002
17Neuraminidase (Sialidase)IBA
01/2018 - 09/2004
15CytokinesIBA
12/2016 - 09/2004
12Antiviral Agents (Antivirals)IBA
12/2016 - 10/2006
11AntibodiesIBA
02/2024 - 12/2005
10AerosolsIBA
12/2022 - 05/2011
9Influenza Vaccines (Influenza Vaccine)FDA Link
01/2019 - 06/2006
6AntigensIBA
02/2024 - 08/2002
6InterferonsIBA
12/2016 - 05/2009
5N-Acetylneuraminic Acid (Sialic Acid)IBA
01/2019 - 05/2008
5Immune Sera (Antisera)IBA
10/2018 - 10/2006
5Oseltamivir (Tamiflu)FDA Link
10/2015 - 03/2008
5ChemokinesIBA
10/2013 - 10/2008
4DNA (Deoxyribonucleic Acid)IBA
01/2017 - 08/2010
4Zanamivir (Relenza)FDA Link
02/2014 - 03/2008
4Interferon Type IIBA
01/2011 - 11/2007
3Neutralizing AntibodiesIBA
04/2015 - 08/2002
3MicroRNAs (MicroRNA)IBA
12/2011 - 03/2010
3EpitopesIBA
10/2011 - 06/2006
3Monoclonal AntibodiesIBA
10/2011 - 10/2006
3Interleukin-1 (Interleukin 1)IBA
12/2010 - 03/2007
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2010 - 03/2007
3Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
12/2010 - 03/2007
2Small Interfering RNA (siRNA)IBA
12/2016 - 06/2004
2Liposomes (Liposome)IBA
05/2016 - 06/2006
2DNA VaccinesIBA
01/2015 - 08/2002
2RNA (Ribonucleic Acid)IBA
12/2014 - 01/2011
2Messenger RNA (mRNA)IBA
01/2011 - 08/2002
2Membrane Proteins (Integral Membrane Proteins)IBA
11/2010 - 03/2009
2NucleoproteinsIBA
03/2010 - 11/2005
2Interferon-betaIBA
02/2010 - 06/2009
2Interferon-alpha (Interferon Alfa)IBA
04/2009 - 10/2007
2Chemokine CCL3IBA
03/2007 - 08/2002
2Complementary DNA (cDNA)IBA
10/2004 - 09/2004
1factor AIBA
01/2022
1avian influenza A virus hemagglutininIBA
01/2018
1gag Gene Products (gag Protein)IBA
01/2017
1Combined VaccinesIBA
01/2017
1Viral HemagglutininsIBA
03/2016
1Amino AcidsFDA Link
01/2016
1Virus ReceptorsIBA
09/2014
1Aligeron (AS 2)IBA
09/2014
1Glutamine (L-Glutamine)FDA Link
02/2014
1Immunoglobulin A (IgA)IBA
12/2013
1Immunoglobulin G (IgG)IBA
12/2013
1Nitric Oxide (Nitrogen Monoxide)FDA Link
05/2013
1omega-N-Methylarginine (NG Monomethyl L Arginine)IBA
05/2013
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2013
1Simvastatin (Zocor)FDA LinkGeneric
04/2013
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
04/2013
1Subunit VaccinesIBA
03/2013
1Retinoid X Receptors (Retinoid X Receptor)IBA
11/2012
1Interferon Regulatory FactorsIBA
07/2012
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
07/2012
1H1N1 virus hemagglutininIBA
10/2011
1SuspensionsIBA
05/2011
1Aerosolized Particles and DropletsIBA
05/2011
1Chemokine CCL5IBA
04/2011
1PolymersIBA
03/2011
1NucleotidesIBA
01/2011
1Complement System Proteins (Complement)IBA
12/2010
1ProteomeIBA
11/2010
1nasIBA
10/2010
1Transforming Growth Factors (Transforming Growth Factor)IBA
10/2010
1LipoxinsIBA
08/2010
1IgYIBA
04/2010
1Immunoglobulins (Immunoglobulin)IBA
04/2010
1Ion Channels (Ion Channel)IBA
03/2010
1poly(isobutylene-alt-maleic anhydride)IBA
02/2010
1Interferon Receptors (Interferon Receptor)IBA
02/2010
1Interferon-gamma (Interferon, gamma)IBA
02/2010
1oplunofuspIBA
11/2009
1LipidsIBA
10/2009
1Phosphotransferases (Kinase)IBA
05/2009
1Viral ProteinsIBA
01/2009
1N,N-dodecyl,methyl-polyethylenimineIBA
03/2008

Therapy/Procedure

7Therapeutics
09/2014 - 10/2006