Hideki Tsuboi Selected Research

Postmenopausal Osteoporosis

1/2024	An investigation of the differential therapeutic effects of romosozumab on postmenopausal osteoporosis patients with or without rheumatoid arthritis complications: a case-control study.
3/2023	Baseline serum PINP level is associated with the increase in hip bone mineral density seen with Romosozumab treatment in previously untreated women with osteoporosis.
11/2022	Impact of the duration of previous osteoporosis treatment on the effect of romosozumab in patients with postmenopausal osteoporosis.
10/2021	Effects of prior osteoporosis treatment on 12-month treatment response of romosozumab in patients with postmenopausal osteoporosis.
3/2021	Effects of follow-on therapy after denosumab discontinuation in patients with postmenopausal osteoporosis.
11/2020	Effects of prior osteoporosis treatment on early treatment response of romosozumab in patients with postmenopausal osteoporosis.

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Hideki Tsuboi Research Topics

Disease

34	Rheumatoid Arthritis 01/2024 - 12/2005
13	Congenital Abnormalities (Deformity) 01/2024 - 01/2014
7	Osteoporosis 01/2024 - 11/2020
7	Hallux Valgus 01/2023 - 01/2014
6	Postmenopausal Osteoporosis 01/2024 - 11/2020
6	Arthritis (Polyarthritis) 01/2022 - 01/2006
3	Osteoarthritis 01/2024 - 01/2020
3	Pain (Aches) 01/2022 - 01/2020
2	Infections 06/2023 - 05/2013
2	Inflammation (Inflammations) 11/2022 - 01/2007
2	Experimental Arthritis 01/2007 - 01/2006
2	Neoplasms (Cancer) 01/2004 - 11/2002
1	Flatfoot (Flat Feet) 01/2024
1	Wounds and Injuries (Trauma) 06/2023
1	Ankylosis 09/2018
1	Osteolysis 05/2014
1	Surgical Wound Infection 05/2014
1	Spondylitis 05/2014
1	Symptom Flare Up 05/2013
1	Hepatitis 12/2011
1	Hepatitis B 12/2011
1	Pancytopenia 10/2011
1	Fever (Fevers) 10/2011
1	Spontaneous Fractures (Pathological Fracture) 01/2009
1	Metabolic Bone Diseases (Osteopenia) 01/2007
1	Bone Resorption 01/2007
1	Chondrosarcoma 11/2002

Drug/Important Bio-Agent (IBA)

5	romosozumabIBA 01/2024 - 11/2020
5	tocilizumab (atlizumab)FDA Link 07/2019 - 12/2011
3	Methotrexate (Mexate)FDA LinkGeneric 07/2019 - 10/2011
2	cyclic citrullinated peptideIBA 01/2024 - 05/2023
2	Peptides (Polypeptides)IBA 05/2023 - 01/2015
2	C-Reactive ProteinIBA 11/2022 - 05/2014
2	Prednisolone (Predate)FDA LinkGeneric 11/2022 - 10/2011
2	Capsules (Microcapsules)IBA 01/2020 - 05/2018
2	LigandsIBA 01/2019 - 01/2006
2	Durapatite (Hydroxylapatite)IBA 01/2018 - 01/2009
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2007 - 01/2006
2	Macrophage Colony-Stimulating FactorIBA 01/2006 - 12/2005
1	Therapeutic UsesIBA 01/2024
1	ametantrone (HAQ)IBA 01/2024
1	Abatacept (Orencia)FDA Link 05/2023
1	MineralsIBA 03/2023
1	SiliconesIBA 01/2023
1	GlucocorticoidsIBA 11/2022
1	Indicators and Reagents (Reagents)IBA 11/2022
1	Serum AlbuminIBA 11/2022
1	Teriparatide (Parathar)FDA Link 03/2021
1	Diphosphonates (Bisphosphonates)IBA 03/2021
1	Denosumab FDA Link 03/2021
1	1- hydroxy- 5,8- bis(2- ((2- hydroxyethyl)amino)ethylamino)- 9,10- anthracenedioneIBA 01/2021
1	iguratimodIBA 07/2019
1	glucose utilization inhibitor (IGU)IBA 07/2019
1	Interleukin-8 (Interleukin 8)IBA 01/2019
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2017
1	CytokinesIBA 06/2015
1	CD100 antigenIBA 06/2015
1	Anti-Bacterial Agents (Antibiotics)IBA 05/2014
1	Lamivudine (Epivir)FDA Link 12/2011
1	Infliximab (Remicade)FDA Link 12/2011
1	Transaminases (Aminotransferases)IBA 12/2011
1	Leucovorin (Folinic Acid)FDA Link 10/2011
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 10/2011
1	Interleukin-6 (Interleukin 6)IBA 12/2009
1	OsteopontinIBA 12/2009
1	Indomethacin (Indometacin)FDA LinkGeneric 01/2007
1	Celecoxib (Celebrex)FDA Link 01/2007
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2007
1	Imatinib Mesylate (Gleevec)FDA Link 01/2006
1	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 01/2006
1	Complementary DNA (cDNA)IBA 01/2004
1	Messenger RNA (mRNA)IBA 11/2002
1	Aggrecans (Aggrecan)IBA 11/2002
1	RNA IsoformsIBA 11/2002
1	Protein Isoforms (Isoforms)IBA 11/2002

Therapy/Procedure

12	Osteotomy 01/2024 - 11/2017
8	Arthroplasty 01/2024 - 12/2017
3	Arthrodesis 12/2018 - 01/2014
2	Debridement 06/2023 - 05/2014
2	Operative Surgical Procedures 01/2022 - 10/2021
1	Postoperative Care 01/2024
1	Local Anesthesia 06/2023
1	Aftercare (After-Treatment) 01/2022
1	Reoperation 10/2021
1	Therapeutics 03/2021
1	Activities of Daily Living (ADL) 01/2021
1	Drug Therapy (Chemotherapy) 11/2017
1	Perioperative Period 05/2013
1	Curettage 01/2009