Paul C Trippier Selected Research

Prodrugs

1/2023

Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model.

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Paul C Trippier Research Topics

Disease

7	Neoplasms (Cancer) 04/2024 - 08/2016
5	Prostatic Neoplasms (Prostate Cancer) 04/2024 - 06/2015
5	Ischemic Stroke 04/2024 - 01/2021
4	Stroke (Strokes) 10/2023 - 01/2021
3	Alzheimer Disease (Alzheimer's Disease) 10/2022 - 01/2019
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 01/2019
3	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2018 - 04/2013
2	Pain (Aches) 06/2023 - 01/2022
2	Neuroinflammatory Diseases 01/2022 - 01/2022
2	Triple Negative Breast Neoplasms 01/2021 - 01/2021
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2019 - 08/2016
2	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 09/2018 - 01/2016
1	Hematologic Neoplasms (Hematological Malignancy) 04/2024
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2022
1	Disease Progression 01/2022
1	Parkinson Disease (Parkinson's Disease) 01/2022
1	Multiple Sclerosis 01/2022
1	Encephalomyelitis (Myeloencephalitis) 01/2022
1	Nervous System Diseases (Neurological Disorders) 11/2021
1	Atrophy 11/2020
1	Gliosis 11/2020
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 11/2019
1	Leukemia 11/2019
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/2019
1	Substance-Related Disorders (Drug Abuse) 10/2018
1	Obesity 10/2018
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 10/2018
1	Adenocarcinoma 01/2018
1	B-Cell Lymphoma (Lymphoma, B Cell) 12/2017
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 09/2014

Drug/Important Bio-Agent (IBA)

5	Aldo-Keto ReductasesIBA 04/2024 - 01/2018
5	neurolysinIBA 04/2024 - 01/2022
4	Peptide Hydrolases (Proteases)FDA Link 04/2024 - 11/2021
4	EnzymesIBA 06/2023 - 11/2019
3	Protein Isoforms (Isoforms)IBA 06/2023 - 01/2018
3	Antineoplastic Agents (Antineoplastics)IBA 01/2023 - 01/2018
3	AndrogensIBA 01/2023 - 01/2018
2	Androgen Receptors (Androgen Receptor)IBA 04/2024 - 01/2018
2	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2019
2	PeptidomimeticsIBA 10/2023 - 07/2022
2	Carbonic Anhydrases (Carbonic Anhydrase)IBA 06/2023 - 01/2022
2	Urea (Carbamide)FDA LinkGeneric 01/2022 - 01/2021
2	Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA 01/2022 - 01/2019
2	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2019
2	CeramidesIBA 11/2020 - 09/2018
2	flupirtineIBA 11/2020 - 09/2018
2	Prostate-Specific Antigen (Semenogelase)IBA 01/2020 - 01/2018
2	Daunorubicin (Cerubidine)FDA LinkGeneric 11/2019 - 08/2016
2	CarbamatesIBA 09/2018 - 12/2017
1	LigandsIBA 06/2023
1	ProdrugsIBA 01/2023
1	NitrogenIBA 10/2022
1	NeuropeptidesIBA 07/2022
1	Oxygen (Dioxygen)IBA 01/2022
1	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2022
1	Dopamine (Intropin)FDA LinkGeneric 01/2022
1	Angiogenesis InhibitorsIBA 01/2022
1	Dopamine Agents (Dopaminergic Agents)IBA 01/2022
1	Fluorouracil (Carac)FDA LinkGeneric 01/2021
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021
1	Progestins (Progestagens)IBA 01/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021
1	Lipid PeroxidesIBA 01/2021
1	Diazoxide (Hyperstat)FDA Link 01/2021
1	Estrogens (Estrogen)FDA Link 01/2021
1	LipofuscinIBA 10/2020
1	mitochondrial ATPase subunit cIBA 10/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	apalutamideIBA 01/2020
1	Androgen Antagonists (Antiandrogens)IBA 01/2020
1	darolutamideIBA 01/2020
1	AnthracyclinesIBA 11/2019
1	Cytarabine (Cytosar-U)FDA LinkGeneric 11/2019
1	Methamphetamine (Desoxyn)FDA LinkGeneric 10/2018
1	AcidsIBA 01/2018
1	enzalutamideIBA 01/2018
1	Therapeutic UsesIBA 01/2018
1	Hydroxysteroid DehydrogenasesIBA 01/2018
1	Apoptosis Regulatory ProteinsIBA 12/2017
1	Etoposide (VP 16)FDA LinkGeneric 08/2016
1	Organophosphonates (Phosphonates)IBA 04/2016
1	Proteasome Endopeptidase Complex (Proteasome)IBA 09/2014
1	pyrazoloneIBA 09/2014

Therapy/Procedure

13	Therapeutics 04/2024 - 04/2013
5	Castration 04/2024 - 06/2015
1	Intravenous Administration 07/2022
1	Drug Tapering 11/2019
1	Drug Therapy (Chemotherapy) 08/2016