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J B Trepel Selected Research

Transforming Growth Factor beta (TGF-beta)

2/2001MS-275, a histone deacetylase inhibitor, selectively induces transforming growth factor beta type II receptor expression in human breast cancer cells.

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J B Trepel Research Topics

Disease

5Neoplasms (Cancer)
10/2016 - 07/2000
3Leukemia
12/2007 - 07/2000
2Carcinoma (Carcinomatosis)
03/2001 - 07/2000
2Breast Neoplasms (Breast Cancer)
02/2001 - 07/2000
1Colorectal Neoplasms (Colorectal Cancer)
10/2016
1Carcinogenesis
10/2016
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2016
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2007
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2001
1Nasopharyngeal Carcinoma
12/2001
1Prostatic Neoplasms (Prostate Cancer)
10/2001
1Primitive Neuroectodermal Tumors (PNET)
12/2000
1Ewing Sarcoma (Sarcoma, Ewing)
12/2000

Drug/Important Bio-Agent (IBA)

2Messenger RNA (mRNA)IBA
10/2016 - 02/2001
2Complementary DNA (cDNA)IBA
12/2001 - 10/2001
1Eukaryotic Initiation Factor-4EIBA
10/2016
1Irinotecan (Camptosar)FDA LinkGeneric
10/2016
1LY 2275796IBA
10/2016
1Peptide Initiation Factors (Initiation Factor)IBA
10/2016
1Antisense OligonucleotidesIBA
10/2016
1Erlotinib Hydrochloride (CP 358,774)FDA Link
04/2016
1AZD 6244IBA
04/2016
1Proteins (Proteins, Gene)FDA Link
11/2012
1Protein Kinases (Protein Kinase)IBA
11/2012
1beta CateninIBA
12/2007
1Tyrosine (L-Tyrosine)FDA Link
12/2007
1Folic Acid (Vitamin M)FDA LinkGeneric
12/2001
1Sirolimus (Rapamycin)FDA Link
10/2001
1AndrogensIBA
10/2001
1Hormones (Hormone)IBA
10/2001
1bcr-abl Fusion ProteinsIBA
10/2001
1geldanamycinIBA
10/2001
1apicidinIBA
03/2001
1Transforming Growth Factor beta (TGF-beta)IBA
02/2001
1Histones (Histone)IBA
02/2001
1Histone Deacetylases (Histone Deacetylase)IBA
02/2001
1Transforming Growth Factors (Transforming Growth Factor)IBA
02/2001
1Transforming Growth Factor-beta Type II ReceptorIBA
02/2001
1Transforming Growth Factor-beta Type I ReceptorIBA
02/2001
1entinostat (MS 275)IBA
02/2001
1Histone Deacetylase InhibitorsIBA
02/2001
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
12/2000
1Lovastatin (Mevacor)FDA LinkGeneric
12/2000
1Retinoblastoma ProteinIBA
12/2000
1Proteasome Endopeptidase Complex (Proteasome)IBA
07/2000
1CalpainIBA
07/2000
1Proteasome InhibitorsIBA
07/2000
1Peptide Hydrolases (Proteases)FDA Link
07/2000
1Bortezomib (Velcade)FDA Link
07/2000
1Protease Inhibitors (Protease Inhibitor)IBA
07/2000
1CathepsinsIBA
07/2000

Therapy/Procedure

2Therapeutics
11/2012 - 10/2001
1Drug Therapy (Chemotherapy)
10/2001