Masakazu Toi Selected Research

Cyclophosphamide (Cytoxan)

4/2020	A randomized study comparing docetaxel/cyclophosphamide (TC), 5-fluorouracil/epirubicin/cyclophosphamide (FEC) followed by TC, and TC followed by FEC for patients with hormone receptor-positive HER2-negative primary breast cancer.
1/2020	Multicenter study of primary systemic therapy with docetaxel, cyclophosphamide and trastuzumab for HER2-positive operable breast cancer: the JBCRG-10 study.
9/2019	Neoadjuvant exemestane or exemestane plus docetaxel and cyclophosphamide tailored by clinicopathological response to 12 weeks' exemestane exposure in patients with estrogen receptor-positive breast cancer: A multicenter, open-label, phase II study.
2/2019	Differential Involvement of Autophagy and Apoptosis in Response to Chemoendocrine and Endocrine Therapy in Breast Cancer: JBCRG-07TR.
1/2019	Efficacy of Scalp Cooling in Preventing and Recovering From Chemotherapy-Induced Alopecia in Breast Cancer Patients: The HOPE Study.
7/2018	Neoadjuvant endocrine therapy with exemestane followed by response-guided combination therapy with low-dose cyclophosphamide in postmenopausal patients with estrogen receptor-positive breast cancer: A multicenter, open-label, phase II study.
5/2018	Costs associated with febrile neutropenia in Japanese patients with primary breast cancer: post-hoc analysis of a randomized clinical trial.
1/2018	A multicenter phase II trial of neoadjuvant letrozole plus low-dose cyclophosphamide in postmenopausal patients with estrogen receptor-positive breast cancer (JBCRG-07): therapeutic efficacy and clinical implications of circulating endothelial cells.
3/2013	Concurrent celecoxib with 5-fluorouracil/epirubicin/cyclophosphamide followed by docetaxel for stages II - III invasive breast cancer: the OOTR-N001 study.
11/2011	Racial differences in acute toxicities of neoadjuvant or adjuvant chemotherapy in patients with early-stage breast cancer.

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Masakazu Toi Research Topics

Disease

309	Breast Neoplasms (Breast Cancer) 05/2024 - 01/2002
169	Neoplasms (Cancer) 04/2024 - 01/2002
25	Neoplasm Metastasis (Metastasis) 01/2023 - 11/2002
20	Neutropenia 01/2023 - 01/2002
15	Disease Progression 06/2023 - 01/2002
13	Triple Negative Breast Neoplasms 02/2024 - 01/2013
12	Carcinoma (Carcinomatosis) 07/2018 - 03/2003
8	Diarrhea 06/2023 - 09/2017
7	Fatigue 02/2024 - 01/2003
7	Carcinogenesis 10/2023 - 10/2002
7	Leukopenia 01/2023 - 01/2002
6	Noninfiltrating Intraductal Carcinoma (DCIS) 09/2023 - 01/2011
5	Hypoxia (Hypoxemia) 01/2020 - 10/2003
4	Lymphatic Metastasis 01/2021 - 11/2002
4	Nausea 01/2020 - 10/2007
4	Febrile Neutropenia 05/2018 - 10/2007
3	Pathologic Complete Response 04/2024 - 01/2006
3	Edema (Dropsy) 03/2024 - 01/2005
3	Stomatitis 11/2017 - 05/2014
3	Residual Neoplasm 10/2016 - 03/2012

Drug/Important Bio-Agent (IBA)

70	Hormones (Hormone)IBA 02/2024 - 04/2002
44	Trastuzumab (Herceptin)FDA Link 05/2024 - 01/2004
39	Estrogen ReceptorsIBA 12/2023 - 09/2002
38	ErbB Receptors (EGF Receptor)IBA 03/2024 - 07/2009
28	Biomarkers (Surrogate Marker)IBA 10/2023 - 08/2004
23	abemaciclibIBA 11/2023 - 09/2017
21	Cyclophosphamide (Cytoxan)FDA LinkGeneric 04/2020 - 03/2003
20	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2002
19	Aromatase InhibitorsIBA 06/2023 - 10/2002
19	human ERBB2 proteinIBA 01/2023 - 03/2007
18	Docetaxel (Taxotere)FDA Link 03/2024 - 01/2003
16	Fulvestrant (Faslodex)FDA Link 04/2024 - 09/2017
16	taxaneIBA 01/2023 - 11/2007
15	AnthracyclinesIBA 03/2024 - 08/2004
15	palbociclibIBA 11/2023 - 12/2015
15	Tamoxifen FDA LinkGeneric 10/2023 - 01/2002
14	Fluorouracil (Carac)FDA LinkGeneric 06/2020 - 04/2002
12	Estrogens (Estrogen)FDA Link 01/2023 - 01/2002
12	Paclitaxel (Taxol)FDA LinkGeneric 01/2023 - 01/2002
12	Letrozole (Femara)FDA LinkGeneric 04/2021 - 03/2005
11	Capecitabine (Xeloda)FDA Link 01/2022 - 03/2002
11	Progesterone Receptors (Progesterone Receptor)IBA 06/2021 - 09/2002
10	Phenobarbital (Luminal)FDA Link 01/2024 - 09/2010
10	eribulin FDA Link 10/2023 - 09/2017
10	pertuzumabIBA 10/2022 - 01/2017
10	Epirubicin (Ellence)FDA LinkGeneric 04/2020 - 02/2004
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 03/2002
10	Aromatase (CYP19)IBA 05/2011 - 07/2002
9	Cyclin-Dependent Kinase 4IBA 05/2024 - 09/2017
9	exemestane (Aromasin)FDA Link 09/2019 - 07/2002
8	Ado-Trastuzumab EmtansineIBA 10/2022 - 01/2017
8	Lapatinib (GW572016)FDA Link 08/2021 - 07/2009
7	Indocyanine Green (Cardio-Green)FDA LinkGeneric 11/2018 - 04/2010
7	Zoledronic Acid (Zometa)FDA Link 04/2018 - 12/2009
6	EnzymesIBA 01/2023 - 02/2002
6	Bevacizumab (Avastin)FDA Link 01/2023 - 03/2012
6	Messenger RNA (mRNA)IBA 07/2018 - 02/2002
6	Transcription Factors (Transcription Factor)IBA 01/2018 - 11/2004
5	Diphosphonates (Bisphosphonates)IBA 06/2024 - 05/2013
5	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2024 - 09/2003
5	Vinorelbine (Navelbine)FDA LinkGeneric 07/2021 - 06/2005
5	Everolimus FDA Link 01/2019 - 05/2014
5	Indicators and Reagents (Reagents)IBA 06/2008 - 04/2002
5	Thymidine PhosphorylaseIBA 03/2005 - 02/2002
4	CytokinesIBA 01/2024 - 02/2011
4	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2023 - 08/2004
4	Immune Checkpoint InhibitorsIBA 12/2022 - 05/2019
4	Taxoids (Taxanes)IBA 10/2022 - 06/2005
4	Epidermal Growth Factor (EGF)IBA 01/2020 - 07/2011
4	Tumor Biomarkers (Tumor Markers)IBA 11/2019 - 04/2004
4	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 07/2018 - 01/2002
4	IsoflavonesIBA 11/2013 - 11/2005
4	Celecoxib (Celebrex)FDA Link 03/2013 - 09/2003
4	Angiogenesis InhibitorsIBA 01/2012 - 09/2003
4	doxifluridineIBA 02/2005 - 03/2002
3	olaparibIBA 02/2024 - 07/2023
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2024 - 08/2004
3	Cisplatin (Platino)FDA LinkGeneric 12/2023 - 01/2002
3	RNA (Ribonucleic Acid)IBA 05/2023 - 01/2013
3	InterferonsIBA 01/2023 - 01/2017
3	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2023 - 06/2018
3	Antineoplastic Agents (Antineoplastics)IBA 01/2021 - 01/2018
3	Protein Isoforms (Isoforms)IBA 12/2018 - 01/2002
3	Estradiol (Delestrogen)FDA LinkGeneric 06/2018 - 01/2002
3	TabletsIBA 01/2018 - 01/2016
3	Coloring Agents (Dyes)IBA 12/2017 - 07/2013
3	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 03/2007 - 03/2002

Therapy/Procedure

153	Therapeutics 04/2024 - 01/2002
61	Drug Therapy (Chemotherapy) 03/2024 - 11/2002
36	Neoadjuvant Therapy 10/2022 - 08/2004
12	Radiotherapy 02/2024 - 03/2012
11	Adjuvant Chemotherapy 02/2024 - 03/2003
9	Segmental Mastectomy (Lumpectomy) 09/2023 - 01/2005
7	Immunotherapy 09/2022 - 09/2003
6	Drug Tapering 01/2022 - 01/2002
5	Aftercare (After-Treatment) 03/2024 - 04/2010
4	Chemoprevention 11/2009 - 10/2002
3	Lymph Node Excision (Lymph Node Dissection) 04/2024 - 11/2008
3	Operative Surgical Procedures 12/2023 - 01/2015
3	Retreatment 09/2022 - 01/2018