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Chun-Feng Tan Selected Research

Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)

10/2013Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.
12/2009Sporadic amyotrophic lateral sclerosis: Widespread multisystem degeneration with TDP-43 pathology in a patient after long-term survival on a respirator.
11/2009[Neuropathological similarities and differences between frontotemporal lobar degeneration with ubiquitin inclusions and amyotrophic lateral sclerosis with dementia].
10/2009Selective occurrence of TDP-43-immunoreactive inclusions in the lower motor neurons in Machado-Joseph disease.
8/2008Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions.
1/2008TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia.
5/2007TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation.
2/2007Familial amyotrophic lateral sclerosis: a SOD1-unrelated Japanese family of bulbar type with Bunina bodies and ubiquitin-positive skein-like inclusions in lower motor neurons.
10/2004Familial amyotrophic lateral sclerosis with bulbar onset and a novel Asp101Tyr Cu/Zn superoxide dismutase gene mutation.
6/2003Primary lateral sclerosis: a rare upper-motor-predominant form of amyotrophic lateral sclerosis often accompanied by frontotemporal lobar degeneration with ubiquitinated neuronal inclusions? Report of an autopsy case and a review of the literature.

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Chun-Feng Tan Research Topics

Disease

10Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
10/2013 - 06/2003
8Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
08/2012 - 06/2003
3Atrophy
08/2012 - 07/2003
2Motor Neuron Disease (Primary Lateral Sclerosis)
08/2012 - 10/2009
2Neurodegenerative Diseases (Neurodegenerative Disease)
07/2010 - 10/2009
2Dementia (Dementias)
11/2009 - 04/2008
1Corticobasal Degeneration
07/2010
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
07/2010
1Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
10/2009
1X-Linked Bulbo-Spinal Atrophy
10/2009
1Parkinson Disease (Parkinson's Disease)
04/2008
1Neoplasms (Cancer)
12/2007

Drug/Important Bio-Agent (IBA)

7UbiquitinIBA
08/2012 - 06/2003
6DNA-Binding Proteins (DNA Binding Protein)IBA
10/2013 - 05/2007
2Proteins (Proteins, Gene)FDA Link
07/2010 - 04/2008
2alpha-SynucleinIBA
04/2008 - 07/2003
1U12 small nuclear RNAIBA
10/2013
1Carrier Proteins (Binding Protein)IBA
11/2009
1polyglutamineIBA
10/2009
1Nuclear Proteins (Protein, Nuclear)IBA
08/2008
1Mucin-1 (CA 15-3 Antigen)IBA
12/2007
1Neurofilament ProteinsIBA
12/2007
1VimentinIBA
12/2007
1Glial Fibrillary Acidic ProteinIBA
12/2007
1Superoxide Dismutase-1IBA
10/2004

Therapy/Procedure

2Mechanical Ventilators (Ventilator)
12/2009 - 08/2008